ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	131/746	423/7206	6.96037146356e-34
ko04724	Glutamatergic synapse	71/746	152/7206	4.86068910693e-31
ko05033	Nicotine addiction	41/746	56/7206	5.40523059419e-29
ko05032	Morphine addiction	52/746	110/7206	2.94118123036e-23
ko04728	Dopaminergic synapse	68/746	185/7206	2.43124836913e-22
ko04713	Circadian entrainment	57/746	136/7206	3.76705641677e-22
ko04727	GABAergic synapse	50/746	110/7206	1.88633374904e-21
ko04721	Synaptic vesicle cycle	42/746	80/7206	3.11780390109e-21
ko04723	Retrograde endocannabinoid signaling	60/746	175/7206	4.26824013791e-18
ko04725	Cholinergic synapse	53/746	160/7206	2.21243319386e-15
ko04911	Insulin secretion	44/746	117/7206	3.00449064942e-15
ko04024	cAMP signaling pathway	73/746	279/7206	1.6005390382e-14
ko05031	Amphetamine addiction	35/746	91/7206	1.0167614857e-12
ko04720	Long-term potentiation	35/746	99/7206	1.74474036461e-11
ko04921	Oxytocin signaling pathway	55/746	209/7206	2.62372361729e-11
ko04726	Serotonergic synapse	42/746	137/7206	3.42029683972e-11
ko04261	Adrenergic signaling in cardiomyocytes	54/746	205/7206	3.85141190945e-11
ko04020	Calcium signaling pathway	63/746	265/7206	1.06486871153e-10
ko04970	Salivary secretion	30/746	95/7206	1.06685344144e-08
ko04742	Taste transduction	23/746	61/7206	1.30429801166e-08
ko04060	Cytokine-cytokine receptor interaction	1/746	191/7206	2.34611609804e-08
ko05030	Cocaine addiction	25/746	73/7206	2.94715183008e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	25/746	74/7206	4.0223446769e-08
ko04744	Phototransduction	16/746	36/7206	1.48353259207e-07
ko04010	MAPK signaling pathway	64/746	321/7206	1.58303282261e-07
ko04966	Collecting duct acid secretion	13/746	26/7206	4.09238065633e-07
ko04730	Long-term depression	23/746	78/7206	2.15420015064e-06
ko03040	Spliceosome	1/746	145/7206	3.13040644912e-06
ko04740	Olfactory transduction	23/746	80/7206	3.48641655801e-06
ko04971	Gastric acid secretion	26/746	98/7206	4.27616558708e-06
ko04925	Aldosterone synthesis and secretion	27/746	105/7206	5.34405427179e-06
ko05203	Viral carcinogenesis	9/746	277/7206	1.1799816982e-05
ko04972	Pancreatic secretion	27/746	111/7206	2.11163259477e-05
ko04514	Cell adhesion molecules (CAMs)	30/746	130/7206	2.66093869333e-05
ko05164	Influenza A	3/746	167/7206	2.68515358894e-05
ko05168	Herpes simplex infection	4/746	182/7206	3.48556978595e-05
ko04745	Phototransduction - fly	13/746	38/7206	6.53481586261e-05
ko04072	Phospholipase D signaling pathway	39/746	197/7206	6.76319548982e-05
ko04022	cGMP-PKG signaling pathway	41/746	216/7206	9.71718233813e-05
ko04260	Cardiac muscle contraction	23/746	98/7206	0.000143333978997
ko05110	Vibrio cholerae infection	17/746	63/7206	0.000155166888996
ko04350	TGF-beta signaling pathway	1/746	103/7206	0.000254574417953
ko04621	NOD-like receptor signaling pathway	4/746	157/7206	0.00029390277808
ko04915	Estrogen signaling pathway	27/746	131/7206	0.000404872543637
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/746	79/7206	0.000504722193894
ko04540	Gap junction	26/746	128/7206	0.000636411366997
ko05169	Epstein-Barr virus infection	8/746	206/7206	0.00101925519106
ko04924	Renin secretion	19/746	86/7206	0.00111117558075
ko04070	Phosphatidylinositol signaling system	23/746	112/7206	0.0013858577387
ko04120	Ubiquitin mediated proteolysis	4/746	138/7206	0.00166473016051
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/746	14/7206	0.00174533708158
ko05322	Systemic lupus erythematosus	5/746	151/7206	0.00178055372969
ko03013	RNA transport	6/746	166/7206	0.00184300273431
ko05162	Measles	3/746	120/7206	0.00212043736965
ko05414	Dilated cardiomyopathy	22/746	112/7206	0.00265194668396
ko03008	Ribosome biogenesis in eukaryotes	1/746	79/7206	0.00268364652647
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/746	92/7206	0.00286060101329
ko04110	Cell cycle	5/746	145/7206	0.0034422587255
ko04612	Antigen processing and presentation	1/746	77/7206	0.00399341402494
ko04141	Protein processing in endoplasmic reticulum	8/746	184/7206	0.00449487062055
ko04014	Ras signaling pathway	44/746	279/7206	0.0047212652522
ko04550	Signaling pathways regulating pluripotency of stem cells	7/746	165/7206	0.00625742856389
ko04626	Plant-pathogen interaction	6/746	18/7206	0.00751745681356
ko00512	Mucin type O-glycan biosynthesis	8/746	29/7206	0.0075587233466
ko04964	Proximal tubule bicarbonate reclamation	8/746	29/7206	0.0075587233466
ko04630	Jak-STAT signaling pathway	5/746	132/7206	0.00886232063973
ko04973	Carbohydrate digestion and absorption	10/746	42/7206	0.00906843420949
ko04912	GnRH signaling pathway	22/746	122/7206	0.00978597867916
ko04750	Inflammatory mediator regulation of TRP channels	22/746	122/7206	0.00978597867916
ko05034	Alcoholism	37/746	238/7206	0.0122451633824
ko04640	Hematopoietic cell lineage	1/746	64/7206	0.0125298530157
ko05323	Rheumatoid arthritis	17/746	89/7206	0.0125822427703
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/746	182/7206	0.0131020452207
ko05231	Choline metabolism in cancer	23/746	134/7206	0.0140844057861
ko05016	Huntington's disease	12/746	215/7206	0.016710128738
ko00240	Pyrimidine metabolism	4/746	110/7206	0.0168125144383
ko05215	Prostate cancer	4/746	111/7206	0.0170788213974
ko04510	Focal adhesion	14/746	240/7206	0.0173469857445
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/746	59/7206	0.0176488053103
ko04140	Autophagy - animal	8/746	164/7206	0.0186960585227
ko04330	Notch signaling pathway	1/746	62/7206	0.0188193373406
ko05410	Hypertrophic cardiomyopathy (HCM)	18/746	100/7206	0.0190028876588
ko04360	Axon guidance	35/746	233/7206	0.0214502993149
ko04371	Apelin signaling pathway	28/746	177/7206	0.0234736270986
ko04976	Bile secretion	15/746	80/7206	0.0241137612389
ko04071	Sphingolipid signaling pathway	26/746	162/7206	0.0253372953037
ko04214	Apoptosis - fly	2/746	72/7206	0.0306652895621
ko00310	Lysine degradation	2/746	73/7206	0.0311166692136
ko04145	Phagosome	25/746	162/7206	0.0367521005241
ko05202	Transcriptional misregulation in cancer	11/746	188/7206	0.0387646681705
ko05214	Glioma	14/746	79/7206	0.0395195607518
ko00480	Glutathione metabolism	1/746	55/7206	0.0410742087469
ko05205	Proteoglycans in cancer	18/746	271/7206	0.0416007556785
ko04940	Type I diabetes mellitus	7/746	32/7206	0.0417884636297
ko04064	NF-kappa B signaling pathway	4/746	96/7206	0.0424247841768
ko05161	Hepatitis B	10/746	173/7206	0.0432249791912
ko04015	Rap1 signaling pathway	39/746	278/7206	0.0444970890148
ko03018	RNA degradation	3/746	84/7206	0.0447602536412
ko05166	HTLV-I infection	20/746	292/7206	0.0491156168361
ko04668	TNF signaling pathway	6/746	120/7206	0.0495851123157