ko pathway ratio_in_study ratio_in_pop p_value ko03030 DNA replication 16/178 38/7206 1.35332682365e-16 ko03040 Spliceosome 19/178 145/7206 2.0764998845e-09 ko04110 Cell cycle 16/178 145/7206 4.70988182584e-07 ko00240 Pyrimidine metabolism 12/178 110/7206 1.52275439825e-05 ko04111 Cell cycle - yeast 10/178 90/7206 6.79852144828e-05 ko00230 Purine metabolism 15/178 194/7206 8.2961591374e-05 ko00670 One carbon pool by folate 5/178 20/7206 9.9716868829e-05 ko04612 Antigen processing and presentation 9/178 77/7206 0.000106339667307 ko03430 Mismatch repair 5/178 22/7206 0.000162708123375 ko03013 RNA transport 13/178 166/7206 0.00022001883574 ko03015 mRNA surveillance pathway 9/178 93/7206 0.000451963284124 ko04080 Neuroactive ligand-receptor interaction 1/178 423/7206 0.000501737827334 ko03020 RNA polymerase 5/178 29/7206 0.00063778525988 ko03008 Ribosome biogenesis in eukaryotes 8/178 79/7206 0.000692399198817 ko03420 Nucleotide excision repair 6/178 46/7206 0.000860749148174 ko05217 Basal cell carcinoma 7/178 68/7206 0.00135734217683 ko04113 Meiosis - yeast 7/178 70/7206 0.00161048460523 ko03410 Base excision repair 5/178 38/7206 0.00225296699384 ko01523 Antifolate resistance 4/178 30/7206 0.00597075663981 ko04144 Endocytosis 2/178 342/7206 0.0182071892997 ko05323 Rheumatoid arthritis 6/178 89/7206 0.0223998737809 ko04020 Calcium signaling pathway 1/178 265/7206 0.0231724926544 ko05205 Proteoglycans in cancer 13/178 271/7206 0.0245652821446 ko04010 MAPK signaling pathway 2/178 321/7206 0.0251779246531 ko03460 Fanconi anemia pathway 4/178 51/7206 0.0365598476997 ko04210 Apoptosis 9/178 180/7206 0.0444023079904