ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04727	GABAergic synapse	34/377	110/7206	4.79845396878e-18
ko05033	Nicotine addiction	25/377	56/7206	5.32809536987e-18
ko04744	Phototransduction	20/377	36/7206	4.88196845953e-17
ko04724	Glutamatergic synapse	37/377	152/7206	9.43628832677e-16
ko05032	Morphine addiction	31/377	110/7206	2.77179888253e-15
ko04721	Synaptic vesicle cycle	25/377	80/7206	1.08732199422e-13
ko04723	Retrograde endocannabinoid signaling	35/377	175/7206	3.04123424281e-12
ko04080	Neuroactive ligand-receptor interaction	57/377	423/7206	1.52308280622e-11
ko04728	Dopaminergic synapse	35/377	185/7206	1.62391144255e-11
ko04713	Circadian entrainment	27/377	136/7206	1.23029872517e-09
ko05030	Cocaine addiction	17/377	73/7206	1.36940245145e-07
ko04024	cAMP signaling pathway	36/377	279/7206	5.81371750887e-07
ko04725	Cholinergic synapse	25/377	160/7206	6.98860102302e-07
ko05203	Viral carcinogenesis	1/377	277/7206	6.7323097953e-06
ko04911	Insulin secretion	19/377	117/7206	8.74761790964e-06
ko05205	Proteoglycans in cancer	1/377	271/7206	9.9907878293e-06
ko04726	Serotonergic synapse	20/377	137/7206	2.59770410807e-05
ko04970	Salivary secretion	16/377	95/7206	2.82483671626e-05
ko04261	Adrenergic signaling in cardiomyocytes	24/377	205/7206	0.000176334721768
ko04742	Taste transduction	11/377	61/7206	0.000272587991379
ko04514	Cell adhesion molecules (CAMs)	17/377	130/7206	0.000405147459881
ko04810	Regulation of actin cytoskeleton	3/377	264/7206	0.000627078158392
ko05031	Amphetamine addiction	13/377	91/7206	0.000830803851418
ko05169	Epstein-Barr virus infection	2/377	206/7206	0.00214210416892
ko05164	Influenza A	1/377	167/7206	0.0022842410591
ko04068	FoxO signaling pathway	1/377	167/7206	0.0022842410591
ko04022	cGMP-PKG signaling pathway	22/377	216/7206	0.00265902007545
ko04964	Proximal tubule bicarbonate reclamation	6/377	29/7206	0.00335369167437
ko04921	Oxytocin signaling pathway	21/377	209/7206	0.00387207224859
ko04010	MAPK signaling pathway	29/377	321/7206	0.00429107469634
ko04060	Cytokine-cytokine receptor interaction	2/377	191/7206	0.00439090592315
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/377	182/7206	0.00618502242995
ko04740	Olfactory transduction	10/377	80/7206	0.00848039297518
ko04218	Cellular senescence	2/377	177/7206	0.00902971338033
ko05166	HTLV-I infection	6/377	292/7206	0.0100492012075
ko05034	Alcoholism	22/377	238/7206	0.0106922622472
ko04140	Autophagy - animal	2/377	164/7206	0.0123259738104
ko04972	Pancreatic secretion	12/377	111/7206	0.0153145280354
ko04720	Long-term potentiation	11/377	99/7206	0.0186494018897
ko05016	Huntington's disease	4/377	215/7206	0.0189185817656
ko04925	Aldosterone synthesis and secretion	11/377	105/7206	0.0242756498618
ko04670	Leukocyte transendothelial migration	2/377	151/7206	0.0247582972387
ko05322	Systemic lupus erythematosus	2/377	151/7206	0.0247582972387
ko04510	Focal adhesion	5/377	240/7206	0.0254141515609
ko04217	Necroptosis	3/377	178/7206	0.0257607421097
ko05168	Herpes simplex infection	3/377	182/7206	0.0263254854452
ko00604	Glycosphingolipid biosynthesis - ganglio series	3/377	14/7206	0.0336190774606
ko04110	Cell cycle	2/377	145/7206	0.0352783715069
ko05161	Hepatitis B	3/377	173/7206	0.0358911655869
ko04260	Cardiac muscle contraction	10/377	98/7206	0.0365765221241
ko04371	Apelin signaling pathway	16/377	177/7206	0.0373587360111
ko02024	Quorum sensing	3/377	15/7206	0.0404362786112
ko04350	TGF-beta signaling pathway	1/377	103/7206	0.0439957749005
ko04966	Collecting duct acid secretion	4/377	26/7206	0.0442771459214
ko05110	Vibrio cholerae infection	7/377	63/7206	0.0451952796832
ko04020	Calcium signaling pathway	21/377	265/7206	0.0492282964587
ko04120	Ubiquitin mediated proteolysis	2/377	138/7206	0.0497449188529