ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 24/128 191/7206 1.8955023353e-14 ko05340 Primary immunodeficiency 11/128 30/7206 1.47746271799e-12 ko05162 Measles 16/128 120/7206 2.49501233859e-10 ko04612 Antigen processing and presentation 13/128 77/7206 6.64572070349e-10 ko04650 Natural killer cell mediated cytotoxicity 14/128 97/7206 1.22048036456e-09 ko04659 Th17 cell differentiation 14/128 106/7206 4.03152382195e-09 ko05330 Allograft rejection 8/128 24/7206 4.61077930885e-09 ko05164 Influenza A 17/128 167/7206 4.71658867102e-09 ko04630 Jak-STAT signaling pathway 15/128 132/7206 9.00884527715e-09 ko05168 Herpes simplex infection 17/128 182/7206 1.74939668259e-08 ko05145 Toxoplasmosis 14/128 126/7206 3.89428023405e-08 ko04380 Osteoclast differentiation 14/128 134/7206 8.56494205522e-08 ko04658 Th1 and Th2 cell differentiation 12/128 96/7206 1.03522120709e-07 ko05332 Graft-versus-host disease 6/128 18/7206 4.35376375469e-07 ko05321 Inflammatory bowel disease (IBD) 9/128 56/7206 4.97171188245e-07 ko05320 Autoimmune thyroid disease 7/128 29/7206 5.33760156444e-07 ko04660 T cell receptor signaling pathway 12/128 124/7206 1.73217210235e-06 ko04217 Necroptosis 14/128 178/7206 2.81633408568e-06 ko05152 Tuberculosis 14/128 187/7206 5.03587498736e-06 ko05140 Leishmaniasis 9/128 75/7206 6.20292167022e-06 ko04940 Type I diabetes mellitus 6/128 32/7206 1.73293810164e-05 ko04672 Intestinal immune network for IgA production 6/128 37/7206 4.13385413685e-05 ko03050 Proteasome 7/128 54/7206 4.18850857755e-05 ko04062 Chemokine signaling pathway 13/128 201/7206 5.29556845757e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/128 191/7206 0.000137297688203 ko05310 Asthma 4/128 17/7206 0.000188961912639 ko04064 NF-kappa B signaling pathway 8/128 96/7206 0.000285011346055 ko04620 Toll-like receptor signaling pathway 8/128 100/7206 0.000376971014665 ko04621 NOD-like receptor signaling pathway 10/128 157/7206 0.000452610428091 ko04145 Phagosome 10/128 162/7206 0.000579959241554 ko05161 Hepatitis B 10/128 173/7206 0.000966622871332 ko05144 Malaria 5/128 45/7206 0.00113060693991 ko05160 Hepatitis C 9/128 153/7206 0.00153759668138 ko04664 Fc epsilon RI signaling pathway 6/128 77/7206 0.0023631944189 ko05416 Viral myocarditis 5/128 55/7206 0.00279510792787 ko05133 Pertussis 6/128 87/7206 0.0043592331654 ko04622 RIG-I-like receptor signaling pathway 5/128 62/7206 0.00471124700706 ko05323 Rheumatoid arthritis 6/128 89/7206 0.00487441989398 ko04640 Hematopoietic cell lineage 5/128 64/7206 0.0053971730548 ko05142 Chagas disease (American trypanosomiasis) 7/128 130/7206 0.00822007122041 ko04514 Cell adhesion molecules (CAMs) 7/128 130/7206 0.00822007122041 ko04210 Apoptosis 8/128 180/7206 0.0145652644545 ko05143 African trypanosomiasis 3/128 32/7206 0.0186558556953 ko05150 Staphylococcus aureus infection 3/128 36/7206 0.0255176994101 ko05146 Amoebiasis 5/128 99/7206 0.0310710655952 ko04080 Neuroactive ligand-receptor interaction 2/128 423/7206 0.0344434986625 ko00051 Fructose and mannose metabolism 3/128 42/7206 0.0380144795457 ko05166 HTLV-I infection 10/128 292/7206 0.0392847604222 ko00592 alpha-Linolenic acid metabolism 2/128 19/7206 0.0439600474163 ko01524 Platinum drug resistance 4/128 76/7206 0.0457517794998 ko05202 Transcriptional misregulation in cancer 7/128 188/7206 0.0496242670026