ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 39/360 191/7206 1.7027478566e-14 ko04380 Osteoclast differentiation 32/360 134/7206 4.43791227354e-14 ko05340 Primary immunodeficiency 13/360 30/7206 5.39116830994e-10 ko04650 Natural killer cell mediated cytotoxicity 22/360 97/7206 1.36421770723e-09 ko04660 T cell receptor signaling pathway 22/360 124/7206 1.58532683966e-07 ko05164 Influenza A 26/360 167/7206 1.80721339405e-07 ko04610 Complement and coagulation cascades 17/360 79/7206 2.40026458215e-07 ko05162 Measles 21/360 120/7206 3.88051432961e-07 ko05321 Inflammatory bowel disease (IBD) 14/360 56/7206 4.0025110516e-07 ko05140 Leishmaniasis 16/360 75/7206 6.18329146072e-07 ko04621 NOD-like receptor signaling pathway 24/360 157/7206 7.67222962706e-07 ko05168 Herpes simplex infection 25/360 182/7206 3.40694850127e-06 ko04659 Th17 cell differentiation 18/360 106/7206 4.16902644455e-06 ko05152 Tuberculosis 25/360 187/7206 5.58954722849e-06 ko05150 Staphylococcus aureus infection 10/360 36/7206 6.76648551043e-06 ko04620 Toll-like receptor signaling pathway 17/360 100/7206 7.60862015228e-06 ko04658 Th1 and Th2 cell differentiation 16/360 96/7206 1.82830880532e-05 ko04064 NF-kappa B signaling pathway 16/360 96/7206 1.82830880532e-05 ko04217 Necroptosis 23/360 178/7206 2.33979288236e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 24/360 191/7206 2.48967924057e-05 ko05161 Hepatitis B 22/360 173/7206 4.51793871472e-05 ko05145 Toxoplasmosis 18/360 126/7206 4.81896720899e-05 ko05144 Malaria 10/360 45/7206 5.67409935481e-05 ko05320 Autoimmune thyroid disease 8/360 29/7206 6.10736999978e-05 ko04672 Intestinal immune network for IgA production 9/360 37/7206 6.2757300487e-05 ko04630 Jak-STAT signaling pathway 18/360 132/7206 8.98264165806e-05 ko04612 Antigen processing and presentation 13/360 77/7206 9.72149729891e-05 ko05034 Alcoholism 1/360 238/7206 0.000106684700697 ko04933 AGE-RAGE signaling pathway in diabetic complications 18/360 135/7206 0.000120665091278 ko05330 Allograft rejection 7/360 24/7206 0.000121092020106 ko05133 Pertussis 13/360 87/7206 0.00034421387449 ko04666 Fc gamma R-mediated phagocytosis 16/360 122/7206 0.000346268882612 ko04145 Phagosome 19/360 162/7206 0.000653757853546 ko04611 Platelet activation 19/360 163/7206 0.00067706657123 ko05212 Pancreatic cancer 12/360 83/7206 0.000783854426269 ko04640 Hematopoietic cell lineage 10/360 64/7206 0.00115534180814 ko04662 B cell receptor signaling pathway 12/360 88/7206 0.00132786477338 ko05323 Rheumatoid arthritis 12/360 89/7206 0.00146746967778 ko05332 Graft-versus-host disease 5/360 18/7206 0.00151088656227 ko04670 Leukocyte transendothelial migration 17/360 151/7206 0.00174957639274 ko05131 Shigellosis 11/360 82/7206 0.00238536346987 ko00254 Aflatoxin biosynthesis 2/360 2/7206 0.00248925109254 ko04062 Chemokine signaling pathway 20/360 201/7206 0.00276047233625 ko05142 Chagas disease (American trypanosomiasis) 15/360 130/7206 0.0031973393384 ko03013 RNA transport 1/360 166/7206 0.00333166491522 ko05132 Salmonella infection 12/360 98/7206 0.00335592370424 ko04622 RIG-I-like receptor signaling pathway 9/360 62/7206 0.00339612515883 ko05166 HTLV-I infection 26/360 292/7206 0.00364647936503 ko05160 Hepatitis C 16/360 153/7206 0.00428716152611 ko04664 Fc epsilon RI signaling pathway 10/360 77/7206 0.00470741429119 ko04512 ECM-receptor interaction 10/360 79/7206 0.00566056000697 ko04514 Cell adhesion molecules (CAMs) 14/360 130/7206 0.0064336204786 ko04072 Phospholipase D signaling pathway 19/360 197/7206 0.00677980024857 ko05418 Fluid shear stress and atherosclerosis 17/360 173/7206 0.00696550203462 ko05310 Asthma 4/360 17/7206 0.00868217110004 ko05016 Huntington's disease 3/360 215/7206 0.00991482228053 ko04144 Endocytosis 28/360 342/7206 0.0101976257831 ko04916 Melanogenesis 1/360 142/7206 0.0102267426159 ko04210 Apoptosis 17/360 180/7206 0.0133875881321 ko00590 Arachidonic acid metabolism 7/360 52/7206 0.0140777418968 ko04713 Circadian entrainment 1/360 136/7206 0.0150511654819 ko04623 Cytosolic DNA-sensing pathway 6/360 41/7206 0.0152357404306 ko05202 Transcriptional misregulation in cancer 17/360 188/7206 0.0161851681409 ko04668 TNF signaling pathway 12/360 120/7206 0.0183823275575 ko05416 Viral myocarditis 7/360 55/7206 0.018806845518 ko04940 Type I diabetes mellitus 5/360 32/7206 0.020020976056 ko04911 Insulin secretion 1/360 117/7206 0.0307618631236 ko05200 Pathways in cancer 35/360 492/7206 0.0314491911334 ko05100 Bacterial invasion of epithelial cells 10/360 99/7206 0.0315262095788 ko05146 Amoebiasis 10/360 99/7206 0.0315262095788 ko04015 Rap1 signaling pathway 22/360 278/7206 0.0334892278471 ko04724 Glutamatergic synapse 2/360 152/7206 0.0354693790413 ko05020 Prion diseases 5/360 40/7206 0.0473998087692 ko05010 Alzheimer's disease 4/360 202/7206 0.0474036018755 ko04510 Focal adhesion 19/360 240/7206 0.0478337611838 ko04114 Oocyte meiosis 2/360 139/7206 0.0482654558774 ko00966 Glucosinolate biosynthesis 1/360 1/7206 0.0499583680268