ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko00190	Oxidative phosphorylation	64/861	127/7206	8.1154449523e-27
ko05010	Alzheimer's disease	75/861	202/7206	5.69978828993e-21
ko05012	Parkinson's disease	61/861	155/7206	1.07369023978e-18
ko04080	Neuroactive ligand-receptor interaction	113/861	423/7206	7.67765515201e-18
ko04723	Retrograde endocannabinoid signaling	60/861	175/7206	4.23595873964e-15
ko04020	Calcium signaling pathway	77/861	265/7206	1.73334280817e-14
ko01200	Carbon metabolism	47/861	128/7206	2.44685012969e-13
ko04260	Cardiac muscle contraction	39/861	98/7206	1.44598841023e-12
ko04921	Oxytocin signaling pathway	61/861	209/7206	1.00058893316e-11
ko04022	cGMP-PKG signaling pathway	62/861	216/7206	1.28053156146e-11
ko05016	Huntington's disease	60/861	215/7206	1.20144008736e-10
ko04932	Non-alcoholic fatty liver disease (NAFLD)	53/861	182/7206	2.84246126435e-10
ko04261	Adrenergic signaling in cardiomyocytes	57/861	205/7206	4.22490180505e-10
ko00010	Glycolysis / Gluconeogenesis	29/861	74/7206	1.71057382163e-09
ko04713	Circadian entrainment	41/861	136/7206	8.39937906973e-09
ko04724	Glutamatergic synapse	44/861	152/7206	1.27200049788e-08
ko05168	Herpes simplex infection	2/861	182/7206	4.10567798067e-08
ko04970	Salivary secretion	31/861	95/7206	7.59802921005e-08
ko04911	Insulin secretion	35/861	117/7206	1.29604218649e-07
ko05033	Nicotine addiction	22/861	56/7206	1.52461181695e-07
ko01230	Biosynthesis of amino acids	28/861	85/7206	2.5982507729e-07
ko03040	Spliceosome	1/861	145/7206	3.59728762214e-07
ko04922	Glucagon signaling pathway	36/861	128/7206	5.41559774532e-07
ko00020	Citrate cycle (TCA cycle)	16/861	35/7206	6.72419141557e-07
ko04727	GABAergic synapse	32/861	110/7206	8.97057983179e-07
ko05410	Hypertrophic cardiomyopathy (HCM)	30/861	100/7206	9.5839293061e-07
ko05322	Systemic lupus erythematosus	2/861	151/7206	1.49355915163e-06
ko04971	Gastric acid secretion	29/861	98/7206	1.9821540438e-06
ko03010	Ribosome	1/861	129/7206	2.90553188412e-06
ko04024	cAMP signaling pathway	60/861	279/7206	4.58740560492e-06
ko05032	Morphine addiction	30/861	110/7206	9.09870140875e-06
ko05164	Influenza A	4/861	167/7206	1.01255379239e-05
ko04721	Synaptic vesicle cycle	24/861	80/7206	1.16262555183e-05
ko00680	Methane metabolism	14/861	34/7206	1.50906889935e-05
ko04630	Jak-STAT signaling pathway	2/861	132/7206	1.63385161625e-05
ko05031	Amphetamine addiction	26/861	91/7206	2.21263861549e-05
ko00710	Carbon fixation in photosynthetic organisms	12/861	27/7206	2.45839060154e-05
ko05203	Viral carcinogenesis	13/861	277/7206	4.06474546327e-05
ko05414	Dilated cardiomyopathy	29/861	112/7206	4.38576648968e-05
ko04725	Cholinergic synapse	37/861	160/7206	5.94589128942e-05
ko04060	Cytokine-cytokine receptor interaction	7/861	191/7206	9.58430513271e-05
ko04110	Cell cycle	4/861	145/7206	0.000133186266647
ko04371	Apelin signaling pathway	39/861	177/7206	0.000135983906484
ko04924	Renin secretion	23/861	86/7206	0.000145399647347
ko04144	Endocytosis	20/861	342/7206	0.000155592489718
ko00030	Pentose phosphate pathway	12/861	32/7206	0.000180681714599
ko00620	Pyruvate metabolism	15/861	46/7206	0.000181593058798
ko04720	Long-term potentiation	25/861	99/7206	0.000226394665126
ko04730	Long-term depression	21/861	78/7206	0.000272475107346
ko04964	Proximal tubule bicarbonate reclamation	11/861	29/7206	0.000298791264057
ko05162	Measles	3/861	120/7206	0.000314535815021
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/861	79/7206	0.000314874214408
ko04657	IL-17 signaling pathway	1/861	87/7206	0.000343861538853
ko04270	Vascular smooth muscle contraction	34/861	154/7206	0.00035165481638
ko05161	Hepatitis B	7/861	173/7206	0.000492315285122
ko00071	Fatty acid degradation	14/861	45/7206	0.000511706239762
ko04742	Taste transduction	17/861	61/7206	0.000568407156668
ko04960	Aldosterone-regulated sodium reabsorption	13/861	41/7206	0.000658081647012
ko04728	Dopaminergic synapse	38/861	185/7206	0.00075249855318
ko04726	Serotonergic synapse	30/861	137/7206	0.00078047658913
ko04120	Ubiquitin mediated proteolysis	5/861	138/7206	0.00084325531845
ko00051	Fructose and mannose metabolism	13/861	42/7206	0.000850646436157
ko05014	Amyotrophic lateral sclerosis (ALS)	19/861	74/7206	0.000920027795089
ko03013	RNA transport	7/861	166/7206	0.000936595425402
ko04710	Circadian rhythm	13/861	43/7206	0.0010883257901
ko04745	Phototransduction - fly	12/861	38/7206	0.00109777333134
ko05140	Leishmaniasis	1/861	75/7206	0.0017732588968
ko00362	Benzoate degradation	4/861	6/7206	0.00248864129582
ko04626	Plant-pathogen interaction	7/861	18/7206	0.00328162190017
ko04925	Aldosterone synthesis and secretion	23/861	105/7206	0.0034746287672
ko05220	Chronic myeloid leukemia	2/861	85/7206	0.00349489808569
ko04141	Protein processing in endoplasmic reticulum	10/861	184/7206	0.00378658939758
ko05200	Pathways in cancer	39/861	492/7206	0.00386225718074
ko01212	Fatty acid metabolism	15/861	60/7206	0.00426640195939
ko05169	Epstein-Barr virus infection	12/861	206/7206	0.00434729457738
ko04210	Apoptosis	10/861	180/7206	0.0050122312239
ko00220	Arginine biosynthesis	8/861	24/7206	0.00510776559761
ko04330	Notch signaling pathway	1/861	62/7206	0.00543060467989
ko05166	HTLV-I infection	20/861	292/7206	0.00547116668886
ko04390	Hippo signaling pathway	11/861	188/7206	0.00614023454037
ko00500	Starch and sucrose metabolism	10/861	35/7206	0.00628081355037
ko04550	Signaling pathways regulating pluripotency of stem cells	9/861	165/7206	0.00713382942101
ko04972	Pancreatic secretion	23/861	111/7206	0.00730808116205
ko04350	TGF-beta signaling pathway	4/861	103/7206	0.00840419617641
ko04514	Cell adhesion molecules (CAMs)	26/861	130/7206	0.00871618658517
ko04966	Collecting duct acid secretion	8/861	26/7206	0.00873812519395
ko04917	Prolactin signaling pathway	3/861	87/7206	0.011324882838
ko00250	Alanine, aspartate and glutamate metabolism	10/861	38/7206	0.011620590983
ko04620	Toll-like receptor signaling pathway	4/861	100/7206	0.0118061136692
ko05321	Inflammatory bowel disease (IBD)	1/861	56/7206	0.0118571744571
ko04621	NOD-like receptor signaling pathway	9/861	157/7206	0.0123963402843
ko00640	Propanoate metabolism	9/861	34/7206	0.0157025480915
ko04658	Th1 and Th2 cell differentiation	4/861	96/7206	0.0161500242997
ko05142	Chagas disease (American trypanosomiasis)	7/861	130/7206	0.0192875931695
ko04391	Hippo signaling pathway - fly	4/861	90/7206	0.0217607655414
ko05230	Central carbon metabolism in cancer	17/861	81/7206	0.0229525818043
ko01040	Biosynthesis of unsaturated fatty acids	7/861	25/7206	0.0235401691118
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/861	59/7206	0.0246910078926
ko01522	Endocrine resistance	7/861	124/7206	0.0251599378231
ko01210	2-Oxocarboxylic acid metabolism	6/861	20/7206	0.0253421820104
ko04152	AMPK signaling pathway	29/861	161/7206	0.0258946472702
ko04540	Gap junction	24/861	128/7206	0.0264159336873
ko05215	Prostate cancer	6/861	111/7206	0.0270578707622
ko04973	Carbohydrate digestion and absorption	10/861	42/7206	0.028032535863
ko04622	RIG-I-like receptor signaling pathway	2/861	62/7206	0.029200219311
ko05221	Acute myeloid leukemia	2/861	63/7206	0.0295872968713
ko04668	TNF signaling pathway	7/861	120/7206	0.0332602868735
ko04740	Olfactory transduction	16/861	80/7206	0.0355557551389
ko03420	Nucleotide excision repair	1/861	46/7206	0.0377695605687
ko04070	Phosphatidylinositol signaling system	21/861	112/7206	0.0379756032027
ko05224	Breast cancer	12/861	174/7206	0.0431211498374
ko00720	Carbon fixation pathways in prokaryotes	5/861	17/7206	0.0436780709156
ko00380	Tryptophan metabolism	11/861	50/7206	0.044331392524
ko05110	Vibrio cholerae infection	13/861	63/7206	0.0476262021118
ko04914	Progesterone-mediated oocyte maturation	6/861	104/7206	0.0478251591798
ko04659	Th17 cell differentiation	6/861	106/7206	0.0482645141569
ko04978	Mineral absorption	9/861	40/7206	0.0488900218482