ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 20/183 157/7206 2.06765409529e-09 ko05164 Influenza A 20/183 167/7206 6.16890912213e-09 ko04668 TNF signaling pathway 13/183 120/7206 9.73390854936e-06 ko04622 RIG-I-like receptor signaling pathway 9/183 62/7206 2.29377676841e-05 ko04060 Cytokine-cytokine receptor interaction 16/183 191/7206 2.51040087024e-05 ko04064 NF-kappa B signaling pathway 11/183 96/7206 2.82870383398e-05 ko05161 Hepatitis B 15/183 173/7206 3.03047017162e-05 ko05160 Hepatitis C 14/183 153/7206 3.08697778686e-05 ko04380 Osteoclast differentiation 13/183 134/7206 3.22178459469e-05 ko04620 Toll-like receptor signaling pathway 11/183 100/7206 4.15932677828e-05 ko05162 Measles 12/183 120/7206 4.83762304643e-05 ko05168 Herpes simplex infection 15/183 182/7206 5.480864505e-05 ko04623 Cytosolic DNA-sensing pathway 7/183 41/7206 6.57567425608e-05 ko04658 Th1 and Th2 cell differentiation 10/183 96/7206 0.000148383218638 ko04210 Apoptosis 14/183 180/7206 0.000181341610035 ko05150 Staphylococcus aureus infection 6/183 36/7206 0.000255251838905 ko04660 T cell receptor signaling pathway 11/183 124/7206 0.000292749821683 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/183 191/7206 0.000336140357269 ko05321 Inflammatory bowel disease (IBD) 7/183 56/7206 0.000492115607768 ko04612 Antigen processing and presentation 8/183 77/7206 0.000699474786577 ko05131 Shigellosis 8/183 82/7206 0.00106380449544 ko05145 Toxoplasmosis 10/183 126/7206 0.0013147195838 ko05323 Rheumatoid arthritis 8/183 89/7206 0.00181333639763 ko04217 Necroptosis 12/183 178/7206 0.00184536955389 ko04630 Jak-STAT signaling pathway 10/183 132/7206 0.00186825340066 ko04672 Intestinal immune network for IgA production 5/183 37/7206 0.00225371116406 ko05152 Tuberculosis 12/183 187/7206 0.00278793925779 ko05140 Leishmaniasis 7/183 75/7206 0.00281098134512 ko00140 Steroid hormone biosynthesis 5/183 41/7206 0.00357041637693 ko04657 IL-17 signaling pathway 7/183 87/7206 0.00641926214431 ko05133 Pertussis 7/183 87/7206 0.00641926214431 ko05340 Primary immunodeficiency 4/183 30/7206 0.00658106820328 ko04662 B cell receptor signaling pathway 7/183 88/7206 0.00682829284677 ko05134 Legionellosis 6/183 74/7206 0.0109726273152 ko04115 p53 signaling pathway 6/183 74/7206 0.0109726273152 ko05132 Salmonella infection 7/183 98/7206 0.0120531731955 ko00120 Primary bile acid biosynthesis 3/183 20/7206 0.0133617409313 ko04610 Complement and coagulation cascades 6/183 79/7206 0.0148462668714 ko04659 Th17 cell differentiation 7/183 106/7206 0.0179495044224 ko04062 Chemokine signaling pathway 11/183 201/7206 0.018444433475 ko00051 Fructose and mannose metabolism 4/183 42/7206 0.0212518073527 ko05215 Prostate cancer 7/183 111/7206 0.0225291046013 ko04917 Prolactin signaling pathway 6/183 87/7206 0.0228706156533 ko04931 Insulin resistance 8/183 137/7206 0.0230426571222 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/183 92/7206 0.0291422520983 ko04650 Natural killer cell mediated cytotoxicity 6/183 97/7206 0.0364534707295 ko05142 Chagas disease (American trypanosomiasis) 7/183 130/7206 0.0471739717723