ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	150/848	423/7206	5.58447472379e-40
ko04724	Glutamatergic synapse	79/848	152/7206	1.17621488182e-34
ko05033	Nicotine addiction	46/848	56/7206	6.63795236812e-34
ko04727	GABAergic synapse	61/848	110/7206	5.33278888549e-29
ko05032	Morphine addiction	59/848	110/7206	4.94150515968e-27
ko04723	Retrograde endocannabinoid signaling	70/848	175/7206	3.50095995741e-22
ko04728	Dopaminergic synapse	72/848	185/7206	5.89475320374e-22
ko04713	Circadian entrainment	60/848	136/7206	9.63064049545e-22
ko04744	Phototransduction	27/848	36/7206	1.84330029817e-18
ko04725	Cholinergic synapse	61/848	160/7206	3.18604420997e-18
ko04721	Synaptic vesicle cycle	38/848	80/7206	1.66817785983e-15
ko04024	cAMP signaling pathway	80/848	279/7206	4.85715425584e-15
ko04726	Serotonergic synapse	48/848	137/7206	5.80325566961e-13
ko04921	Oxytocin signaling pathway	62/848	209/7206	1.25677376813e-12
ko04911	Insulin secretion	42/848	117/7206	6.74843209005e-12
ko04020	Calcium signaling pathway	70/848	265/7206	2.03412582988e-11
ko04261	Adrenergic signaling in cardiomyocytes	59/848	205/7206	2.30091560117e-11
ko04742	Taste transduction	28/848	61/7206	2.60167193454e-11
ko05031	Amphetamine addiction	34/848	91/7206	2.02373721158e-10
ko05030	Cocaine addiction	27/848	73/7206	1.94790968716e-08
ko04720	Long-term potentiation	32/848	99/7206	4.19343203333e-08
ko04970	Salivary secretion	30/848	95/7206	1.98904537041e-07
ko03040	Spliceosome	1/848	145/7206	3.49728573544e-07
ko05203	Viral carcinogenesis	9/848	277/7206	4.99475259463e-07
ko04060	Cytokine-cytokine receptor interaction	4/848	191/7206	1.09210338722e-06
ko04260	Cardiac muscle contraction	29/848	98/7206	1.44811027984e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/848	79/7206	1.97899986638e-06
ko05164	Influenza A	3/848	167/7206	2.40327309166e-06
ko04740	Olfactory transduction	25/848	80/7206	2.56314190413e-06
ko04971	Gastric acid secretion	28/848	98/7206	4.69734651334e-06
ko04010	MAPK signaling pathway	65/848	321/7206	7.58201145385e-06
ko04925	Aldosterone synthesis and secretion	29/848	105/7206	8.43932923933e-06
ko04120	Ubiquitin mediated proteolysis	2/848	138/7206	1.15014338944e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	22/848	74/7206	2.46348464105e-05
ko04514	Cell adhesion molecules (CAMs)	32/848	130/7206	4.2964131304e-05
ko04072	Phospholipase D signaling pathway	43/848	197/7206	4.35803037146e-05
ko04972	Pancreatic secretion	28/848	111/7206	7.21284560452e-05
ko03013	RNA transport	5/848	166/7206	7.64885283935e-05
ko05322	Systemic lupus erythematosus	4/848	151/7206	9.50046253371e-05
ko04621	NOD-like receptor signaling pathway	5/848	157/7206	0.000223253159505
ko04022	cGMP-PKG signaling pathway	44/848	216/7206	0.000227184474904
ko04730	Long-term depression	21/848	78/7206	0.000236829084059
ko05168	Herpes simplex infection	7/848	182/7206	0.000256406721213
ko05169	Epstein-Barr virus infection	9/848	206/7206	0.000268222617926
ko05414	Dilated cardiomyopathy	27/848	112/7206	0.000275606462841
ko05162	Measles	3/848	120/7206	0.000472323771919
ko04141	Protein processing in endoplasmic reticulum	8/848	184/7206	0.000685462412266
ko05205	Proteoglycans in cancer	15/848	271/7206	0.000696582461792
ko04745	Phototransduction - fly	12/848	38/7206	0.000957965319901
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/848	182/7206	0.000962409667266
ko03008	Ribosome biogenesis in eukaryotes	1/848	79/7206	0.00117811284741
ko05166	HTLV-I infection	18/848	292/7206	0.00153120678069
ko05161	Hepatitis B	8/848	173/7206	0.00172844833267
ko04924	Renin secretion	20/848	86/7206	0.00217353181027
ko04214	Apoptosis - fly	1/848	72/7206	0.00257848460872
ko04350	TGF-beta signaling pathway	3/848	103/7206	0.00288724962288
ko03018	RNA degradation	2/848	84/7206	0.0033454703714
ko05410	Hypertrophic cardiomyopathy (HCM)	22/848	100/7206	0.00418215580562
ko05215	Prostate cancer	4/848	111/7206	0.00430062058656
ko04964	Proximal tubule bicarbonate reclamation	9/848	29/7206	0.00467147625117
ko04064	NF-kappa B signaling pathway	3/848	96/7206	0.00582476177348
ko04110	Cell cycle	7/848	145/7206	0.00592167914841
ko04915	Estrogen signaling pathway	26/848	131/7206	0.0060375124446
ko04630	Jak-STAT signaling pathway	6/848	132/7206	0.00607375468713
ko04612	Antigen processing and presentation	2/848	77/7206	0.00697239907709
ko04070	Phosphatidylinositol signaling system	23/848	112/7206	0.0070713060449
ko04550	Signaling pathways regulating pluripotency of stem cells	9/848	165/7206	0.00964220372314
ko04750	Inflammatory mediator regulation of TRP channels	24/848	122/7206	0.0101182819368
ko05140	Leishmaniasis	2/848	75/7206	0.0102797778967
ko04540	Gap junction	25/848	128/7206	0.0117520359553
ko04360	Axon guidance	40/848	233/7206	0.0127792743399
ko05200	Pathways in cancer	41/848	492/7206	0.0135540874116
ko04014	Ras signaling pathway	46/848	279/7206	0.0173750539383
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/848	14/7206	0.0179686262102
ko00480	Glutathione metabolism	1/848	55/7206	0.0182031097305
ko05034	Alcoholism	40/848	238/7206	0.0182692408017
ko04510	Focal adhesion	17/848	240/7206	0.0190248342495
ko04140	Autophagy - animal	10/848	164/7206	0.019514080165
ko04142	Lysosome	9/848	151/7206	0.0213938526602
ko05224	Breast cancer	11/848	174/7206	0.0229635568908
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/848	59/7206	0.0230518060204
ko05016	Huntington's disease	15/848	215/7206	0.0239257427275
ko05145	Toxoplasmosis	7/848	126/7206	0.0252887085571
ko04966	Collecting duct acid secretion	7/848	26/7206	0.0269036977931
ko04710	Circadian rhythm	10/848	43/7206	0.029307493958
ko04640	Hematopoietic cell lineage	2/848	64/7206	0.029762517359
ko04930	Type II diabetes mellitus	12/848	54/7206	0.0301279585576
ko04146	Peroxisome	4/848	89/7206	0.0301419463345
ko05222	Small cell lung cancer	4/848	89/7206	0.0301419463345
ko05231	Choline metabolism in cancer	24/848	134/7206	0.0304017177761
ko01524	Platinum drug resistance	3/848	76/7206	0.0304638429395
ko04976	Bile secretion	16/848	80/7206	0.0337631170759
ko04210	Apoptosis	12/848	180/7206	0.0339907925433
ko00240	Pyrimidine metabolism	6/848	110/7206	0.0362194687616
ko00620	Pyruvate metabolism	1/848	46/7206	0.0377330525506
ko03420	Nucleotide excision repair	1/848	46/7206	0.0377330525506
ko00270	Cysteine and methionine metabolism	1/848	47/7206	0.0381290686942
ko00260	Glycine, serine and threonine metabolism	1/848	48/7206	0.0390724813454
ko05219	Bladder cancer	1/848	48/7206	0.0390724813454
ko05218	Melanoma	4/848	85/7206	0.0410551543637
ko04657	IL-17 signaling pathway	4/848	87/7206	0.0421600413845
ko00310	Lysine degradation	3/848	73/7206	0.0425831608358
ko00330	Arginine and proline metabolism	2/848	61/7206	0.0427720739764
ko04062	Chemokine signaling pathway	33/848	201/7206	0.0450250770317
ko04978	Mineral absorption	9/848	40/7206	0.0459577069866
ko04150	mTOR signaling pathway	13/848	184/7206	0.0479633335182