ko pathway ratio_in_study ratio_in_pop p_value ko04721 Synaptic vesicle cycle 17/343 80/7206 1.45209789886e-07 ko04145 Phagosome 23/343 162/7206 2.11558835239e-06 ko04360 Axon guidance 27/343 233/7206 1.4307886142e-05 ko04966 Collecting duct acid secretion 8/343 26/7206 1.78445813852e-05 ko05130 Pathogenic Escherichia coli infection 13/343 77/7206 5.92538102148e-05 ko05120 Epithelial cell signaling in Helicobacter pylori infection 14/343 92/7206 0.000100745113818 ko04728 Dopaminergic synapse 21/343 185/7206 0.00028203518102 ko04950 Maturity onset diabetes of the young 7/343 29/7206 0.000327476900863 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 5/343 15/7206 0.000479741570578 ko04330 Notch signaling pathway 10/343 62/7206 0.000615535675103 ko04961 Endocrine and other factor-regulated calcium reabsorption 9/343 59/7206 0.00172147219803 ko05032 Morphine addiction 13/343 110/7206 0.00207187978838 ko04550 Signaling pathways regulating pluripotency of stem cells 17/343 165/7206 0.00240290375603 ko05014 Amyotrophic lateral sclerosis (ALS) 10/343 74/7206 0.00247945253067 ko05110 Vibrio cholerae infection 9/343 63/7206 0.00274365913847 ko05033 Nicotine addiction 8/343 56/7206 0.00466309007136 ko04727 GABAergic synapse 12/343 110/7206 0.00585783044934 ko04724 Glutamatergic synapse 15/343 152/7206 0.00622992823263 ko04060 Cytokine-cytokine receptor interaction 2/343 191/7206 0.00884240989298 ko04391 Hippo signaling pathway - fly 10/343 90/7206 0.0100988912942 ko04514 Cell adhesion molecules (CAMs) 13/343 130/7206 0.0103757641725 ko04723 Retrograde endocannabinoid signaling 16/343 175/7206 0.0107457546846 ko04911 Insulin secretion 12/343 117/7206 0.0126618652054 ko04713 Circadian entrainment 13/343 136/7206 0.0137233249142 ko05202 Transcriptional misregulation in cancer 16/343 188/7206 0.0222709062623 ko04611 Platelet activation 2/343 163/7206 0.0247071007002 ko05132 Salmonella infection 10/343 98/7206 0.025845652192 ko05100 Bacterial invasion of epithelial cells 10/343 99/7206 0.0266425208952 ko04261 Adrenergic signaling in cardiomyocytes 17/343 205/7206 0.0280388887584 ko04066 HIF-1 signaling pathway 1/343 123/7206 0.0309179918068 ko05224 Breast cancer 14/343 174/7206 0.0465829322196 ko05162 Measles 1/343 120/7206 0.046673644295 ko04964 Proximal tubule bicarbonate reclamation 4/343 29/7206 0.0468143359979 ko04666 Fc gamma R-mediated phagocytosis 11/343 122/7206 0.0481590102366