ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04110	Cell cycle	62/450	145/7206	2.20503230881e-37
ko04111	Cell cycle - yeast	43/450	90/7206	1.4812369823e-28
ko03030	DNA replication	29/450	38/7206	4.76587541909e-28
ko03040	Spliceosome	53/450	145/7206	6.17458645647e-28
ko03460	Fanconi anemia pathway	28/450	51/7206	4.31250880895e-21
ko03440	Homologous recombination	24/450	41/7206	3.8516184541e-19
ko04113	Meiosis - yeast	30/450	70/7206	1.55339344935e-18
ko03013	RNA transport	43/450	166/7206	2.39266649727e-16
ko03430	Mismatch repair	16/450	22/7206	2.18174039986e-15
ko03410	Base excision repair	20/450	38/7206	6.35538690313e-15
ko03420	Nucleotide excision repair	19/450	46/7206	7.73994329775e-12
ko00240	Pyrimidine metabolism	27/450	110/7206	4.07040592993e-10
ko04144	Endocytosis	1/450	342/7206	6.82284929844e-09
ko03015	mRNA surveillance pathway	21/450	93/7206	1.76344558691e-07
ko04218	Cellular senescence	28/450	177/7206	4.0737650024e-06
ko04114	Oocyte meiosis	24/450	139/7206	4.2785927612e-06
ko05166	HTLV-I infection	38/450	292/7206	1.75799010692e-05
ko04115	p53 signaling pathway	15/450	74/7206	4.05489709345e-05
ko05010	Alzheimer's disease	1/450	202/7206	4.61608732858e-05
ko04914	Progesterone-mediated oocyte maturation	18/450	104/7206	6.58049494056e-05
ko00230	Purine metabolism	27/450	194/7206	6.7573102983e-05
ko03008	Ribosome biogenesis in eukaryotes	15/450	79/7206	8.97835380317e-05
ko04024	cAMP signaling pathway	4/450	279/7206	0.000126784868571
ko04014	Ras signaling pathway	4/450	279/7206	0.000126784868571
ko04022	cGMP-PKG signaling pathway	2/450	216/7206	0.000157728789365
ko04810	Regulation of actin cytoskeleton	4/450	264/7206	0.000372672482006
ko04621	NOD-like receptor signaling pathway	1/450	157/7206	0.000694523392526
ko04510	Focal adhesion	4/450	240/7206	0.000999243167129
ko04724	Glutamatergic synapse	1/450	152/7206	0.00102392775853
ko04270	Vascular smooth muscle contraction	1/450	154/7206	0.00104959189349
ko05203	Viral carcinogenesis	31/450	277/7206	0.00136669565367
ko04360	Axon guidance	4/450	233/7206	0.00139793513238
ko04723	Retrograde endocannabinoid signaling	2/450	175/7206	0.0021564971138
ko04015	Rap1 signaling pathway	6/450	278/7206	0.00216196422489
ko04713	Circadian entrainment	1/450	136/7206	0.00335120373589
ko00190	Oxidative phosphorylation	1/450	127/7206	0.00469237911466
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/450	182/7206	0.00484536721501
ko05152	Tuberculosis	3/450	187/7206	0.00506722478879
ko03022	Basal transcription factors	8/450	44/7206	0.0052535941412
ko03018	RNA degradation	12/450	84/7206	0.00562862380438
ko05012	Parkinson's disease	2/450	155/7206	0.00621306528486
ko04010	MAPK signaling pathway	9/450	321/7206	0.0063373378801
ko00670	One carbon pool by folate	5/450	20/7206	0.00658071265806
ko04120	Ubiquitin mediated proteolysis	17/450	138/7206	0.0065967014996
ko04151	PI3K-Akt signaling pathway	12/450	390/7206	0.00672778681778
ko04072	Phospholipase D signaling pathway	4/450	197/7206	0.0101463110782
ko04931	Insulin resistance	2/450	137/7206	0.0120306217643
ko04659	Th17 cell differentiation	1/450	106/7206	0.0142813816177
ko04925	Aldosterone synthesis and secretion	1/450	105/7206	0.0142880588932
ko04727	GABAergic synapse	1/450	110/7206	0.0148596553884
ko05032	Morphine addiction	1/450	110/7206	0.0148596553884
ko04630	Jak-STAT signaling pathway	2/450	132/7206	0.0170726537826
ko04380	Osteoclast differentiation	2/450	134/7206	0.017348758072
ko05206	MicroRNAs in cancer	19/450	177/7206	0.0177321064509
ko04261	Adrenergic signaling in cardiomyocytes	5/450	205/7206	0.0182845198099
ko04725	Cholinergic synapse	3/450	160/7206	0.0189018218836
ko04520	Adherens junction	1/450	103/7206	0.0213111641028
ko05145	Toxoplasmosis	2/450	126/7206	0.0241520318854
ko04062	Chemokine signaling pathway	5/450	201/7206	0.0250214025062
ko05222	Small cell lung cancer	11/450	89/7206	0.025166618888
ko04142	Lysosome	3/450	151/7206	0.0254995248312
ko04371	Apelin signaling pathway	4/450	177/7206	0.0258639129403
ko05219	Bladder cancer	7/450	48/7206	0.0281556684823
ko05016	Huntington's disease	6/450	215/7206	0.0309314040977
ko04971	Gastric acid secretion	1/450	98/7206	0.0315762671838
ko04668	TNF signaling pathway	2/450	120/7206	0.0340908617089
ko04750	Inflammatory mediator regulation of TRP channels	2/450	122/7206	0.0348415321289
ko04666	Fc gamma R-mediated phagocytosis	2/450	122/7206	0.0348415321289
ko04066	HIF-1 signaling pathway	2/450	123/7206	0.0353670655728
ko01523	Antifolate resistance	5/450	30/7206	0.0362607893926
ko04921	Oxytocin signaling pathway	6/450	209/7206	0.040938700155
ko04924	Renin secretion	1/450	86/7206	0.0431273607427
ko04146	Peroxisome	1/450	89/7206	0.043802144185
ko04728	Dopaminergic synapse	5/450	185/7206	0.0439304773914
ko05031	Amphetamine addiction	1/450	91/7206	0.0450411736517
ko04611	Platelet activation	4/450	163/7206	0.0470479503227
ko04972	Pancreatic secretion	2/450	111/7206	0.0472277878056
ko05231	Choline metabolism in cancer	3/450	134/7206	0.0476999892352
ko04726	Serotonergic synapse	3/450	137/7206	0.0479589868382
ko04530	Tight junction	7/450	228/7206	0.0497037659437