ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	141/878	423/7206	2.58416709402e-32
ko04724	Glutamatergic synapse	70/878	152/7206	1.12557197047e-25
ko05033	Nicotine addiction	40/878	56/7206	7.32540095419e-25
ko05032	Morphine addiction	54/878	110/7206	1.13621206714e-21
ko04727	GABAergic synapse	52/878	110/7206	5.74525679657e-20
ko04713	Circadian entrainment	58/878	136/7206	2.03751028806e-19
ko04723	Retrograde endocannabinoid signaling	64/878	175/7206	3.30753727425e-17
ko04728	Dopaminergic synapse	64/878	185/7206	7.91603108192e-16
ko04024	cAMP signaling pathway	83/878	279/7206	1.07493466567e-15
ko04725	Cholinergic synapse	54/878	160/7206	4.95310906354e-13
ko04721	Synaptic vesicle cycle	35/878	80/7206	1.3493034121e-12
ko04020	Calcium signaling pathway	74/878	265/7206	1.82253903962e-12
ko04921	Oxytocin signaling pathway	61/878	209/7206	2.00137990196e-11
ko05031	Amphetamine addiction	33/878	91/7206	2.29630139295e-09
ko05030	Cocaine addiction	28/878	73/7206	8.99629753182e-09
ko04726	Serotonergic synapse	41/878	137/7206	1.88359424477e-08
ko04911	Insulin secretion	36/878	117/7206	6.370551658e-08
ko04720	Long-term potentiation	32/878	99/7206	9.60597141501e-08
ko03040	Spliceosome	1/878	145/7206	2.25935691943e-07
ko04742	Taste transduction	23/878	61/7206	2.77247769903e-07
ko04261	Adrenergic signaling in cardiomyocytes	51/878	205/7206	3.56132957283e-07
ko04022	cGMP-PKG signaling pathway	53/878	216/7206	3.86532105764e-07
ko04744	Phototransduction	16/878	36/7206	1.40558422722e-06
ko03010	Ribosome	1/878	129/7206	1.79487650981e-06
ko04730	Long-term depression	25/878	78/7206	2.89308247525e-06
ko05322	Systemic lupus erythematosus	3/878	151/7206	7.27572963123e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	23/878	74/7206	1.27587218742e-05
ko04925	Aldosterone synthesis and secretion	29/878	105/7206	1.42830715666e-05
ko04970	Salivary secretion	27/878	95/7206	1.87663264303e-05
ko04710	Circadian rhythm	16/878	43/7206	2.22357322479e-05
ko05164	Influenza A	5/878	167/7206	3.64607337612e-05
ko04010	MAPK signaling pathway	64/878	321/7206	5.0927989191e-05
ko04060	Cytokine-cytokine receptor interaction	7/878	191/7206	6.77408563545e-05
ko05169	Epstein-Barr virus infection	9/878	206/7206	0.000138888792098
ko05203	Viral carcinogenesis	15/878	277/7206	0.00016287991465
ko03013	RNA transport	6/878	166/7206	0.000166239201546
ko04971	Gastric acid secretion	25/878	98/7206	0.000247893044899
ko05162	Measles	3/878	120/7206	0.000326989009115
ko04110	Cell cycle	5/878	145/7206	0.000434268105817
ko04930	Type II diabetes mellitus	16/878	54/7206	0.00048293843984
ko04514	Cell adhesion molecules (CAMs)	30/878	130/7206	0.000570793080306
ko03008	Ribosome biogenesis in eukaryotes	1/878	79/7206	0.000756609895167
ko04120	Ubiquitin mediated proteolysis	5/878	138/7206	0.000854087206813
ko04072	Phospholipase D signaling pathway	40/878	197/7206	0.000869884370786
ko04915	Estrogen signaling pathway	29/878	131/7206	0.00108927033116
ko04070	Phosphatidylinositol signaling system	26/878	112/7206	0.00109470241412
ko05168	Herpes simplex infection	9/878	182/7206	0.00121602940351
ko04924	Renin secretion	21/878	86/7206	0.00137815192251
ko04923	Regulation of lipolysis in adipocytes	19/878	77/7206	0.00228487549202
ko04966	Collecting duct acid secretion	9/878	26/7206	0.00257509164666
ko04711	Circadian rhythm - fly	6/878	13/7206	0.00258288808017
ko04141	Protein processing in endoplasmic reticulum	10/878	184/7206	0.00281916437757
ko04360	Axon guidance	44/878	233/7206	0.00293590189948
ko05161	Hepatitis B	9/878	173/7206	0.00300015906824
ko04540	Gap junction	27/878	128/7206	0.00379520087168
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/878	14/7206	0.00405889395967
ko04621	NOD-like receptor signaling pathway	8/878	157/7206	0.00419860051225
ko04745	Phototransduction - fly	11/878	38/7206	0.00440823973064
ko04750	Inflammatory mediator regulation of TRP channels	26/878	122/7206	0.00464156674689
ko04972	Pancreatic secretion	24/878	111/7206	0.00482100774932
ko02010	ABC transporters	11/878	39/7206	0.00547947710016
ko04350	TGF-beta signaling pathway	4/878	103/7206	0.00585644599194
ko05166	HTLV-I infection	21/878	292/7206	0.00601435706353
ko05215	Prostate cancer	5/878	111/7206	0.00825843794181
ko05110	Vibrio cholerae infection	15/878	63/7206	0.0100596894692
ko04217	Necroptosis	11/878	178/7206	0.0103963503195
ko04064	NF-kappa B signaling pathway	4/878	96/7206	0.0113328469332
ko04550	Signaling pathways regulating pluripotency of stem cells	10/878	165/7206	0.0113356789243
ko00520	Amino sugar and nucleotide sugar metabolism	1/878	55/7206	0.0117621496638
ko05414	Dilated cardiomyopathy	23/878	112/7206	0.0122189585607
ko04371	Apelin signaling pathway	33/878	177/7206	0.0138520441607
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/878	79/7206	0.015297173107
ko04260	Cardiac muscle contraction	20/878	98/7206	0.0185233687282
ko04210	Apoptosis	12/878	180/7206	0.0204404197022
ko05200	Pathways in cancer	44/878	492/7206	0.0221663853777
ko05205	Proteoglycans in cancer	21/878	271/7206	0.022654466474
ko05219	Bladder cancer	1/878	48/7206	0.0254398422589
ko00240	Pyrimidine metabolism	6/878	110/7206	0.026873435649
ko04960	Aldosterone-regulated sodium reabsorption	10/878	41/7206	0.0272544107718
ko04071	Sphingolipid signaling pathway	29/878	162/7206	0.0286895350777
ko04630	Jak-STAT signaling pathway	8/878	132/7206	0.0305403260709
ko05140	Leishmaniasis	3/878	75/7206	0.0308885182468
ko04014	Ras signaling pathway	46/878	279/7206	0.0312693790403
ko04216	Ferroptosis	1/878	44/7206	0.0373112565761
ko04740	Olfactory transduction	16/878	80/7206	0.0385717285488
ko05145	Toxoplasmosis	8/878	126/7206	0.0395613027783
ko04510	Focal adhesion	19/878	240/7206	0.0439586792944
ko04218	Cellular senescence	13/878	177/7206	0.0473896188755