ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 7/93 30/7206 7.58895559375e-08 ko04380 Osteoclast differentiation 12/93 134/7206 1.2040429873e-07 ko05152 Tuberculosis 13/93 187/7206 6.7324004492e-07 ko05164 Influenza A 12/93 167/7206 1.32312885322e-06 ko04620 Toll-like receptor signaling pathway 9/93 100/7206 4.86945410118e-06 ko04060 Cytokine-cytokine receptor interaction 12/93 191/7206 5.42003461297e-06 ko04612 Antigen processing and presentation 8/93 77/7206 5.76250255483e-06 ko04672 Intestinal immune network for IgA production 6/93 37/7206 6.61603016773e-06 ko05168 Herpes simplex infection 11/93 182/7206 1.98450110572e-05 ko04650 Natural killer cell mediated cytotoxicity 8/93 97/7206 3.20580424689e-05 ko05150 Staphylococcus aureus infection 5/93 36/7206 8.83038100107e-05 ko05133 Pertussis 7/93 87/7206 0.000119875553308 ko05160 Hepatitis C 9/93 153/7206 0.000145657852133 ko05162 Measles 8/93 120/7206 0.000146306615207 ko04660 T cell receptor signaling pathway 8/93 124/7206 0.000183788645642 ko05330 Allograft rejection 4/93 24/7206 0.000226707083146 ko04062 Chemokine signaling pathway 10/93 201/7206 0.000245266015214 ko05144 Malaria 5/93 45/7206 0.000261149538366 ko05161 Hepatitis B 9/93 173/7206 0.000366471399825 ko04217 Necroptosis 9/93 178/7206 0.000451963284127 ko05320 Autoimmune thyroid disease 4/93 29/7206 0.00048233846882 ko04210 Apoptosis 9/93 180/7206 0.000490471983689 ko04610 Complement and coagulation cascades 6/93 79/7206 0.000512147985426 ko05416 Viral myocarditis 5/93 55/7206 0.000671825318797 ko05321 Inflammatory bowel disease (IBD) 5/93 56/7206 0.000730251120856 ko05167 Kaposi's sarcoma-associated herpesvirus infection 9/93 191/7206 0.000753702004654 ko04621 NOD-like receptor signaling pathway 8/93 157/7206 0.000901310714894 ko05323 Rheumatoid arthritis 6/93 89/7206 0.000965756009424 ko05145 Toxoplasmosis 7/93 126/7206 0.00115278947085 ko05310 Asthma 3/93 17/7206 0.00124128043553 ko04514 Cell adhesion molecules (CAMs) 7/93 130/7206 0.00138345713136 ko04630 Jak-STAT signaling pathway 7/93 132/7206 0.00151158375332 ko05140 Leishmaniasis 5/93 75/7206 0.00272273058029 ko05166 HTLV-I infection 10/93 292/7206 0.00421253055518 ko04668 TNF signaling pathway 6/93 120/7206 0.00441357731593 ko04145 Phagosome 7/93 162/7206 0.00478338976911 ko05142 Chagas disease (American trypanosomiasis) 6/93 130/7206 0.00650366773129 ko04064 NF-kappa B signaling pathway 5/93 96/7206 0.00780535714571 ko04622 RIG-I-like receptor signaling pathway 4/93 62/7206 0.00819780682202 ko05132 Salmonella infection 5/93 98/7206 0.00849967371481 ko04664 Fc epsilon RI signaling pathway 4/93 77/7206 0.0171899536858 ko04071 Sphingolipid signaling pathway 6/93 162/7206 0.0179831512511 ko04666 Fc gamma R-mediated phagocytosis 5/93 122/7206 0.0204074178382 ko04137 Mitophagy - animal 4/93 82/7206 0.0211678892367 ko05212 Pancreatic cancer 4/93 83/7206 0.0220257380658 ko05332 Graft-versus-host disease 2/93 18/7206 0.0220443867482 ko04917 Prolactin signaling pathway 4/93 87/7206 0.0256687187936 ko00120 Primary bile acid biosynthesis 2/93 20/7206 0.0269236133468 ko04933 AGE-RAGE signaling pathway in diabetic complications 5/93 135/7206 0.0299910578909 ko05146 Amoebiasis 4/93 99/7206 0.0386753189608 ko04072 Phospholipase D signaling pathway 6/93 197/7206 0.0414705596633 ko04142 Lysosome 5/93 151/7206 0.0451699134862 ko04670 Leukocyte transendothelial migration 5/93 151/7206 0.0451699134862 ko05322 Systemic lupus erythematosus 5/93 151/7206 0.0451699134862 ko05221 Acute myeloid leukemia 3/93 63/7206 0.0474236435263 ko04659 Th17 cell differentiation 4/93 106/7206 0.047725971818