ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 31/315 233/7206 2.1320762263e-08 ko05033 Nicotine addiction 12/315 56/7206 3.89604859017e-06 ko05032 Morphine addiction 16/315 110/7206 2.02037488867e-05 ko04950 Maturity onset diabetes of the young 8/315 29/7206 2.34042279197e-05 ko04514 Cell adhesion molecules (CAMs) 17/315 130/7206 4.58248984943e-05 ko05217 Basal cell carcinoma 11/315 68/7206 0.000153590259007 ko04340 Hedgehog signaling pathway 10/315 58/7206 0.000177549455285 ko04550 Signaling pathways regulating pluripotency of stem cells 18/315 165/7206 0.00029412822532 ko05224 Breast cancer 18/315 174/7206 0.000563277257812 ko04721 Synaptic vesicle cycle 11/315 80/7206 0.000657658137724 ko04727 GABAergic synapse 13/315 110/7206 0.000958915343832 ko04723 Retrograde endocannabinoid signaling 17/315 175/7206 0.00197089838116 ko04512 ECM-receptor interaction 10/315 79/7206 0.00217698598552 ko04974 Protein digestion and absorption 11/315 96/7206 0.00297551380896 ko05203 Viral carcinogenesis 3/315 277/7206 0.00377026816663 ko04330 Notch signaling pathway 8/315 62/7206 0.0052596883326 ko04724 Glutamatergic synapse 14/315 152/7206 0.00754738539277 ko03013 RNA transport 1/315 166/7206 0.0106984902321 ko04151 PI3K-Akt signaling pathway 27/315 390/7206 0.0152665692187 ko04391 Hippo signaling pathway - fly 9/315 90/7206 0.0163665020182 ko04728 Dopaminergic synapse 15/315 185/7206 0.0174499834955 ko05130 Pathogenic Escherichia coli infection 8/315 77/7206 0.018656439669 ko04341 Hedgehog signaling pathway - fly 5/315 38/7206 0.0237538060507 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 4/315 26/7206 0.0250320174019 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/315 182/7206 0.0253131294622 ko04145 Phagosome 13/315 162/7206 0.0304228203346 ko04120 Ubiquitin mediated proteolysis 1/315 138/7206 0.0319893363452 ko05161 Hepatitis B 2/315 173/7206 0.0355801151763 ko04964 Proximal tubule bicarbonate reclamation 4/315 29/7206 0.0359214722911 ko04911 Insulin secretion 10/315 117/7206 0.036723937811 ko04961 Endocrine and other factor-regulated calcium reabsorption 6/315 59/7206 0.0429412596322 ko04211 Longevity regulating pathway 1/315 123/7206 0.0446358085334 ko04390 Hippo signaling pathway 14/315 188/7206 0.0452281133319 ko05202 Transcriptional misregulation in cancer 14/315 188/7206 0.0452281133319 ko00190 Oxidative phosphorylation 1/315 127/7206 0.0452740925313 ko04621 NOD-like receptor signaling pathway 2/315 157/7206 0.0486861259445 ko04611 Platelet activation 2/315 163/7206 0.0494764089474