ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	189/1126	423/7206	3.93001336285e-49
ko05032	Morphine addiction	73/1126	110/7206	1.41592982325e-33
ko04724	Glutamatergic synapse	86/1126	152/7206	9.00929656829e-32
ko05033	Nicotine addiction	48/1126	56/7206	3.38131293086e-31
ko04727	GABAergic synapse	69/1126	110/7206	1.66124405665e-29
ko04713	Circadian entrainment	74/1126	136/7206	5.48022486022e-26
ko04728	Dopaminergic synapse	83/1126	185/7206	1.04726782664e-21
ko04723	Retrograde endocannabinoid signaling	80/1126	175/7206	1.36270974946e-21
ko04721	Synaptic vesicle cycle	49/1126	80/7206	1.30180768728e-20
ko04725	Cholinergic synapse	73/1126	160/7206	9.94551641054e-20
ko04742	Taste transduction	38/1126	61/7206	1.28794395021e-16
ko04024	cAMP signaling pathway	98/1126	279/7206	2.50601586083e-16
ko04911	Insulin secretion	55/1126	117/7206	7.43812491446e-16
ko04744	Phototransduction	27/1126	36/7206	2.93946886135e-15
ko04726	Serotonergic synapse	57/1126	137/7206	1.6473580157e-13
ko04020	Calcium signaling pathway	88/1126	265/7206	3.86967598567e-13
ko04921	Oxytocin signaling pathway	72/1126	209/7206	1.00386891866e-11
ko04261	Adrenergic signaling in cardiomyocytes	71/1126	205/7206	1.26417746857e-11
ko04740	Olfactory transduction	38/1126	80/7206	1.59657061531e-11
ko03040	Spliceosome	1/1126	145/7206	8.4445078717e-10
ko05031	Amphetamine addiction	38/1126	91/7206	1.70570130552e-09
ko04970	Salivary secretion	39/1126	95/7206	1.88598424338e-09
ko04720	Long-term potentiation	39/1126	99/7206	7.67830079721e-09
ko04925	Aldosterone synthesis and secretion	38/1126	105/7206	1.86064619002e-07
ko05322	Systemic lupus erythematosus	4/1126	151/7206	3.22807578886e-07
ko05203	Viral carcinogenesis	16/1126	277/7206	4.67954410946e-07
ko04966	Collecting duct acid secretion	15/1126	26/7206	1.03778611039e-06
ko05030	Cocaine addiction	28/1126	73/7206	1.89251021796e-06
ko04971	Gastric acid secretion	34/1126	98/7206	3.32271762586e-06
ko05164	Influenza A	7/1126	167/7206	4.18058585878e-06
ko03013	RNA transport	7/1126	166/7206	6.28675427194e-06
ko04010	MAPK signaling pathway	80/1126	321/7206	9.30854829462e-06
ko04060	Cytokine-cytokine receptor interaction	10/1126	191/7206	1.08989937108e-05
ko04745	Phototransduction - fly	17/1126	38/7206	1.90973460938e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1126	74/7206	3.07271189408e-05
ko04022	cGMP-PKG signaling pathway	57/1126	216/7206	3.5859548199e-05
ko04621	NOD-like receptor signaling pathway	8/1126	157/7206	5.30383109833e-05
ko04972	Pancreatic secretion	34/1126	111/7206	5.72471850643e-05
ko05110	Vibrio cholerae infection	23/1126	63/7206	6.08409733109e-05
ko04070	Phosphatidylinositol signaling system	34/1126	112/7206	6.66999492724e-05
ko04514	Cell adhesion molecules (CAMs)	38/1126	130/7206	7.30355605123e-05
ko04141	Protein processing in endoplasmic reticulum	11/1126	184/7206	7.89100151724e-05
ko04072	Phospholipase D signaling pathway	52/1126	197/7206	8.70040884044e-05
ko04730	Long-term depression	26/1126	78/7206	0.000102413703293
ko05168	Herpes simplex infection	11/1126	182/7206	0.000109331757915
ko04120	Ubiquitin mediated proteolysis	7/1126	138/7206	0.000197494425872
ko04924	Renin secretion	27/1126	86/7206	0.000237935626314
ko03008	Ribosome biogenesis in eukaryotes	2/1126	79/7206	0.000267805383004
ko04146	Peroxisome	3/1126	89/7206	0.000352532147989
ko04260	Cardiac muscle contraction	29/1126	98/7206	0.000388066512909
ko04612	Antigen processing and presentation	2/1126	77/7206	0.000397568739523
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/1126	79/7206	0.00043621652918
ko04976	Bile secretion	25/1126	80/7206	0.000477582521431
ko05162	Measles	6/1126	120/7206	0.000516822683048
ko05414	Dilated cardiomyopathy	32/1126	112/7206	0.000522481243583
ko05140	Leishmaniasis	2/1126	75/7206	0.000597199984512
ko04064	NF-kappa B signaling pathway	4/1126	96/7206	0.000606156208202
ko04360	Axon guidance	56/1126	233/7206	0.000644672916218
ko04110	Cell cycle	9/1126	145/7206	0.00073327044391
ko05169	Epstein-Barr virus infection	16/1126	206/7206	0.000883012858236
ko05161	Hepatitis B	12/1126	173/7206	0.000908254097156
ko04540	Gap junction	34/1126	128/7206	0.00126740451499
ko04610	Complement and coagulation cascades	3/1126	79/7206	0.0015664946058
ko04711	Circadian rhythm - fly	7/1126	13/7206	0.00160754977393
ko05205	Proteoglycans in cancer	25/1126	271/7206	0.00209426081612
ko04710	Circadian rhythm	15/1126	43/7206	0.00213280071363
ko00480	Glutathione metabolism	1/1126	55/7206	0.00215998218491
ko04964	Proximal tubule bicarbonate reclamation	11/1126	29/7206	0.00294178294289
ko00590	Arachidonic acid metabolism	1/1126	52/7206	0.00317059444638
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/1126	59/7206	0.00344612878101
ko05166	HTLV-I infection	29/1126	292/7206	0.00504566547113
ko04750	Inflammatory mediator regulation of TRP channels	31/1126	122/7206	0.00519386116735
ko05144	Malaria	1/1126	45/7206	0.00685274606078
ko00071	Fatty acid degradation	1/1126	45/7206	0.00685274606078
ko03420	Nucleotide excision repair	1/1126	46/7206	0.00691607211977
ko04657	IL-17 signaling pathway	5/1126	87/7206	0.00715484359012
ko05133	Pertussis	5/1126	87/7206	0.00715484359012
ko04915	Estrogen signaling pathway	32/1126	131/7206	0.0073650981029
ko05016	Huntington's disease	20/1126	215/7206	0.0074960650119
ko04630	Jak-STAT signaling pathway	10/1126	132/7206	0.00754612646054
ko05321	Inflammatory bowel disease (IBD)	2/1126	56/7206	0.00863886193334
ko04014	Ras signaling pathway	60/1126	279/7206	0.00887218414738
ko04210	Apoptosis	16/1126	180/7206	0.0092480949495
ko04658	Th1 and Th2 cell differentiation	6/1126	96/7206	0.0099862514451
ko04923	Regulation of lipolysis in adipocytes	21/1126	77/7206	0.0104176773569
ko03022	Basal transcription factors	1/1126	44/7206	0.0105723063103
ko00240	Pyrimidine metabolism	8/1126	110/7206	0.0116771603396
ko05215	Prostate cancer	8/1126	111/7206	0.011729145568
ko00562	Inositol phosphate metabolism	23/1126	89/7206	0.0117840275404
ko00280	Valine, leucine and isoleucine degradation	2/1126	54/7206	0.0128025031118
ko04622	RIG-I-like receptor signaling pathway	3/1126	62/7206	0.0135321234935
ko05131	Shigellosis	5/1126	82/7206	0.0136904482232
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1126	14/7206	0.01395280769
ko00310	Lysine degradation	4/1126	73/7206	0.0139982359839
ko04510	Focal adhesion	24/1126	240/7206	0.0142929269571
ko04932	Non-alcoholic fatty liver disease (NAFLD)	17/1126	182/7206	0.0169932035272
ko05418	Fluid shear stress and atherosclerosis	16/1126	173/7206	0.019177442294
ko00330	Arginine and proline metabolism	3/1126	61/7206	0.0195997840331
ko04217	Necroptosis	17/1126	178/7206	0.0213660034223
ko04140	Autophagy - animal	15/1126	164/7206	0.0216692833768
ko04930	Type II diabetes mellitus	15/1126	54/7206	0.0219184632859
ko00630	Glyoxylate and dicarboxylate metabolism	1/1126	38/7206	0.0229380449342
ko03410	Base excision repair	1/1126	38/7206	0.0229380449342
ko05219	Bladder cancer	2/1126	48/7206	0.0262936680792
ko03018	RNA degradation	6/1126	84/7206	0.032925436051
ko05145	Toxoplasmosis	11/1126	126/7206	0.0343351470426
ko04115	p53 signaling pathway	5/1126	74/7206	0.0351412465714
ko04371	Apelin signaling pathway	38/1126	177/7206	0.0356601451576
ko04620	Toll-like receptor signaling pathway	8/1126	100/7206	0.0363614976474
ko04640	Hematopoietic cell lineage	4/1126	64/7206	0.0369780515931
ko05200	Pathways in cancer	61/1126	492/7206	0.0397018166391
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/1126	92/7206	0.0413370506658
ko04218	Cellular senescence	18/1126	177/7206	0.0458290492041
ko04626	Plant-pathogen interaction	6/1126	18/7206	0.0496653477717