ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03010	Ribosome	72/590	129/7206	2.48534878456e-45
ko03040	Spliceosome	64/590	145/7206	2.52072669969e-32
ko03008	Ribosome biogenesis in eukaryotes	46/590	79/7206	2.80974068787e-30
ko03013	RNA transport	65/590	166/7206	4.33925692177e-29
ko03050	Proteasome	33/590	54/7206	5.90537081324e-23
ko03020	RNA polymerase	21/590	29/7206	2.46716663169e-17
ko03030	DNA replication	21/590	38/7206	8.15772219586e-14
ko00240	Pyrimidine metabolism	34/590	110/7206	3.35160004597e-12
ko04020	Calcium signaling pathway	1/590	265/7206	3.87384211915e-09
ko05169	Epstein-Barr virus infection	43/590	206/7206	5.95016213486e-09
ko03420	Nucleotide excision repair	17/590	46/7206	4.89951789804e-08
ko04024	cAMP signaling pathway	3/590	279/7206	1.57020951911e-07
ko03015	mRNA surveillance pathway	24/590	93/7206	2.55800432032e-07
ko04144	Endocytosis	6/590	342/7206	2.82287729e-07
ko00230	Purine metabolism	38/590	194/7206	3.20597312455e-07
ko04110	Cell cycle	31/590	145/7206	4.77868319318e-07
ko05010	Alzheimer's disease	1/590	202/7206	7.64762936987e-07
ko04022	cGMP-PKG signaling pathway	2/590	216/7206	3.23346288818e-06
ko04261	Adrenergic signaling in cardiomyocytes	2/590	205/7206	6.85359480688e-06
ko03018	RNA degradation	20/590	84/7206	9.70383445038e-06
ko04810	Regulation of actin cytoskeleton	5/590	264/7206	1.69996496856e-05
ko04060	Cytokine-cytokine receptor interaction	2/590	191/7206	2.18603799585e-05
ko04010	MAPK signaling pathway	8/590	321/7206	2.43912648967e-05
ko04725	Cholinergic synapse	1/590	160/7206	2.78393886232e-05
ko03430	Mismatch repair	9/590	22/7206	2.92877705962e-05
ko00970	Aminoacyl-tRNA biosynthesis	13/590	44/7206	3.13613865179e-05
ko05012	Parkinson's disease	1/590	155/7206	4.12359685723e-05
ko03060	Protein export	9/590	23/7206	4.4652806168e-05
ko04724	Glutamatergic synapse	1/590	152/7206	6.33658855784e-05
ko04062	Chemokine signaling pathway	3/590	201/7206	6.55934933433e-05
ko04723	Retrograde endocannabinoid signaling	2/590	175/7206	6.7293685671e-05
ko04510	Focal adhesion	5/590	240/7206	9.86146272958e-05
ko04360	Axon guidance	5/590	233/7206	0.000136147685387
ko04728	Dopaminergic synapse	3/590	185/7206	0.000192600557152
ko04380	Osteoclast differentiation	1/590	134/7206	0.000197354092211
ko04713	Circadian entrainment	1/590	136/7206	0.000199053695613
ko04514	Cell adhesion molecules (CAMs)	1/590	130/7206	0.000291207404414
ko04630	Jak-STAT signaling pathway	1/590	132/7206	0.000298487601142
ko04270	Vascular smooth muscle contraction	2/590	154/7206	0.00030142737644
ko04015	Rap1 signaling pathway	8/590	278/7206	0.00031905903679
ko04623	Cytosolic DNA-sensing pathway	11/590	41/7206	0.000328056281756
ko04151	PI3K-Akt signaling pathway	15/590	390/7206	0.000595165680431
ko04668	TNF signaling pathway	1/590	120/7206	0.000633007203883
ko04912	GnRH signaling pathway	1/590	122/7206	0.000645305324241
ko03460	Fanconi anemia pathway	12/590	51/7206	0.000659586478834
ko04921	Oxytocin signaling pathway	5/590	209/7206	0.000741448010494
ko04068	FoxO signaling pathway	3/590	167/7206	0.000824963709978
ko04014	Ras signaling pathway	9/590	279/7206	0.00110170663613
ko04931	Insulin resistance	2/590	137/7206	0.00134165586636
ko04726	Serotonergic synapse	2/590	137/7206	0.00134165586636
ko04727	GABAergic synapse	1/590	110/7206	0.00137064785136
ko05032	Morphine addiction	1/590	110/7206	0.00137064785136
ko04070	Phosphatidylinositol signaling system	1/590	112/7206	0.00139063497143
ko04072	Phospholipase D signaling pathway	5/590	197/7206	0.00141229701972
ko05142	Chagas disease (American trypanosomiasis)	2/590	130/7206	0.00189628113477
ko04915	Estrogen signaling pathway	2/590	131/7206	0.00190634272447
ko04925	Aldosterone synthesis and secretion	1/590	105/7206	0.00201355749776
ko04530	Tight junction	7/590	228/7206	0.00202914270089
ko04670	Leukocyte transendothelial migration	3/590	151/7206	0.00231780429965
ko04111	Cell cycle - yeast	16/590	90/7206	0.00278790968143
ko03410	Base excision repair	9/590	38/7206	0.00292875819557
ko04620	Toll-like receptor signaling pathway	1/590	100/7206	0.00295439624957
ko04611	Platelet activation	4/590	163/7206	0.00354561961085
ko04666	Fc gamma R-mediated phagocytosis	2/590	122/7206	0.00397263957418
ko04974	Protein digestion and absorption	1/590	96/7206	0.00433041784975
ko05211	Renal cell carcinoma	1/590	96/7206	0.00433041784975
ko04650	Natural killer cell mediated cytotoxicity	1/590	97/7206	0.00436738841966
ko05100	Bacterial invasion of epithelial cells	1/590	99/7206	0.00455076570371
ko05146	Amoebiasis	1/590	99/7206	0.00455076570371
ko04916	Melanogenesis	3/590	142/7206	0.00468754409817
ko05200	Pathways in cancer	24/590	492/7206	0.00474568658666
ko03440	Homologous recombination	9/590	41/7206	0.00504902393063
ko04013	MAPK signaling pathway - fly	2/590	115/7206	0.00559103695466
ko05031	Amphetamine addiction	1/590	91/7206	0.00633232597671
ko04391	Hippo signaling pathway - fly	1/590	90/7206	0.0063342392365
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/590	92/7206	0.00638106605719
ko04113	Meiosis - yeast	13/590	70/7206	0.00642584043666
ko05034	Alcoholism	9/590	238/7206	0.0080186531697
ko04972	Pancreatic secretion	2/590	111/7206	0.00802004011554
ko03022	Basal transcription factors	9/590	44/7206	0.00820126843527
ko04540	Gap junction	3/590	128/7206	0.00895122071276
ko04918	Thyroid hormone synthesis	1/590	86/7206	0.00924636752044
ko00562	Inositol phosphate metabolism	1/590	89/7206	0.00965815525248
ko04659	Th17 cell differentiation	2/590	106/7206	0.0114211804418
ko05145	Toxoplasmosis	3/590	126/7206	0.0127061808161
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/590	182/7206	0.0127787518507
ko04919	Thyroid hormone signaling pathway	4/590	143/7206	0.0129579420412
ko05230	Central carbon metabolism in cancer	1/590	81/7206	0.0134802106577
ko04720	Long-term potentiation	2/590	99/7206	0.0161549175426
ko04520	Adherens junction	2/590	103/7206	0.0166688357823
ko04371	Apelin signaling pathway	6/590	177/7206	0.0171542682207
ko04621	NOD-like receptor signaling pathway	5/590	157/7206	0.0175540893973
ko04750	Inflammatory mediator regulation of TRP channels	3/590	122/7206	0.0179766544411
ko04370	VEGF signaling pathway	1/590	77/7206	0.0197344247524
ko04664	Fc epsilon RI signaling pathway	1/590	77/7206	0.0197344247524
ko04512	ECM-receptor interaction	1/590	79/7206	0.0203922333206
ko04910	Insulin signaling pathway	6/590	172/7206	0.02293988139
ko04064	NF-kappa B signaling pathway	2/590	96/7206	0.022977391404
ko04142	Lysosome	5/590	151/7206	0.0235595007202
ko05132	Salmonella infection	2/590	98/7206	0.0235981192549
ko05231	Choline metabolism in cancer	4/590	134/7206	0.0244799882758
ko04933	AGE-RAGE signaling pathway in diabetic complications	4/590	135/7206	0.0247675818891
ko00310	Lysine degradation	1/590	73/7206	0.0290115432579
ko00010	Glycolysis / Gluconeogenesis	1/590	74/7206	0.0295628726944
ko04146	Peroxisome	2/590	89/7206	0.0322664832308
ko04722	Neurotrophin signaling pathway	6/590	160/7206	0.0397096677262
ko04152	AMPK signaling pathway	6/590	161/7206	0.0400551538278
ko04145	Phagosome	6/590	162/7206	0.0405129434525
ko04660	T cell receptor signaling pathway	4/590	124/7206	0.0452133657093
ko04917	Prolactin signaling pathway	2/590	87/7206	0.0461476761465
ko04657	IL-17 signaling pathway	2/590	87/7206	0.0461476761465