ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 46/322 145/7206 1.08390737333e-27 ko04111 Cell cycle - yeast 30/322 90/7206 5.05839862781e-19 ko03030 DNA replication 18/322 38/7206 4.70725533863e-15 ko04113 Meiosis - yeast 21/322 70/7206 1.23947207274e-12 ko03430 Mismatch repair 10/322 22/7206 1.10760122472e-08 ko03040 Spliceosome 24/322 145/7206 1.99595542665e-08 ko03410 Base excision repair 12/322 38/7206 4.907077208e-08 ko04080 Neuroactive ligand-receptor interaction 1/322 423/7206 7.96351226585e-08 ko03440 Homologous recombination 12/322 41/7206 1.26802573359e-07 ko03008 Ribosome biogenesis in eukaryotes 15/322 79/7206 1.63386358649e-06 ko04218 Cellular senescence 21/322 177/7206 3.70424846526e-05 ko04144 Endocytosis 2/322 342/7206 3.79671567385e-05 ko05217 Basal cell carcinoma 12/322 68/7206 3.93505079775e-05 ko05166 HTLV-I infection 29/322 292/7206 5.76792378044e-05 ko03460 Fanconi anemia pathway 10/322 51/7206 6.87093733153e-05 ko04114 Oocyte meiosis 17/322 139/7206 0.000140723683113 ko03420 Nucleotide excision repair 9/322 46/7206 0.000161761742544 ko03015 mRNA surveillance pathway 13/322 93/7206 0.00022742993596 ko05206 MicroRNAs in cancer 19/322 177/7206 0.000327204092195 ko03013 RNA transport 18/322 166/7206 0.000413847556992 ko04310 Wnt signaling pathway 19/322 181/7206 0.000663892667079 ko00240 Pyrimidine metabolism 13/322 110/7206 0.00117346808675 ko04120 Ubiquitin mediated proteolysis 15/322 138/7206 0.00120734646224 ko04550 Signaling pathways regulating pluripotency of stem cells 17/322 165/7206 0.00155117017179 ko04115 p53 signaling pathway 10/322 74/7206 0.00155303595946 ko04330 Notch signaling pathway 9/322 62/7206 0.00158858277598 ko04261 Adrenergic signaling in cardiomyocytes 1/322 205/7206 0.00160390818723 ko04921 Oxytocin signaling pathway 1/322 209/7206 0.00169634512954 ko04914 Progesterone-mediated oocyte maturation 12/322 104/7206 0.00220973066427 ko04024 cAMP signaling pathway 3/322 279/7206 0.00264289207438 ko04728 Dopaminergic synapse 1/322 185/7206 0.00336548788819 ko04060 Cytokine-cytokine receptor interaction 1/322 191/7206 0.00358911881055 ko03018 RNA degradation 10/322 84/7206 0.00402632297634 ko05203 Viral carcinogenesis 23/322 277/7206 0.00417587600261 ko04723 Retrograde endocannabinoid signaling 1/322 175/7206 0.00488493858071 ko04910 Insulin signaling pathway 1/322 172/7206 0.00743556405079 ko05224 Breast cancer 16/322 174/7206 0.00768046636659 ko04062 Chemokine signaling pathway 2/322 201/7206 0.00882922145886 ko04071 Sphingolipid signaling pathway 1/322 162/7206 0.010628217528 ko05202 Transcriptional misregulation in cancer 16/322 188/7206 0.0114180024577 ko04142 Lysosome 1/322 151/7206 0.0150829259944 ko05160 Hepatitis C 1/322 153/7206 0.0153664532077 ko05200 Pathways in cancer 33/322 492/7206 0.0171616861331 ko05222 Small cell lung cancer 9/322 89/7206 0.0174248575403 ko04371 Apelin signaling pathway 2/322 177/7206 0.0251019217666 ko04510 Focal adhesion 4/322 240/7206 0.0259250657487 ko04151 PI3K-Akt signaling pathway 9/322 390/7206 0.0315278956676 ko04380 Osteoclast differentiation 1/322 134/7206 0.0316331199497 ko04810 Regulation of actin cytoskeleton 5/322 264/7206 0.0334999378869 ko04611 Platelet activation 2/322 163/7206 0.0348069267868 ko04712 Circadian rhythm - plant 2/322 7/7206 0.036014011276 ko04340 Hedgehog signaling pathway 6/322 58/7206 0.043749153011 ko04668 TNF signaling pathway 1/322 120/7206 0.04457244207 ko04912 GnRH signaling pathway 1/322 122/7206 0.0446891330715 ko04750 Inflammatory mediator regulation of TRP channels 1/322 122/7206 0.0446891330715 ko04066 HIF-1 signaling pathway 1/322 123/7206 0.0448702247283 ko05322 Systemic lupus erythematosus 12/322 151/7206 0.0450415381162 ko04660 T cell receptor signaling pathway 1/322 124/7206 0.0451327387796 ko04621 NOD-like receptor signaling pathway 2/322 157/7206 0.0488027295683