ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	115/673	423/7206	3.29475853074e-28
ko05032	Morphine addiction	44/673	110/7206	3.85991895782e-18
ko04727	GABAergic synapse	41/673	110/7206	1.07196357169e-15
ko04725	Cholinergic synapse	49/673	160/7206	1.42298101911e-14
ko04724	Glutamatergic synapse	46/673	152/7206	1.53782555513e-13
ko04911	Insulin secretion	39/673	117/7206	3.72356422557e-13
ko04721	Synaptic vesicle cycle	31/673	80/7206	1.06615485299e-12
ko04020	Calcium signaling pathway	62/673	265/7206	3.51381539828e-12
ko05033	Nicotine addiction	25/673	56/7206	4.02433613682e-12
ko04024	cAMP signaling pathway	64/673	279/7206	4.68582267141e-12
ko04921	Oxytocin signaling pathway	53/673	209/7206	5.28663076934e-12
ko04713	Circadian entrainment	40/673	136/7206	1.70335635724e-11
ko04723	Retrograde endocannabinoid signaling	43/673	175/7206	1.67883429596e-09
ko04728	Dopaminergic synapse	44/673	185/7206	3.23322014323e-09
ko04022	cGMP-PKG signaling pathway	45/673	216/7206	1.66563845874e-07
ko04726	Serotonergic synapse	33/673	137/7206	2.27019061128e-07
ko04970	Salivary secretion	26/673	95/7206	3.10856613064e-07
ko04971	Gastric acid secretion	25/673	98/7206	2.18685897845e-06
ko04261	Adrenergic signaling in cardiomyocytes	40/673	205/7206	7.08192093001e-06
ko04925	Aldosterone synthesis and secretion	25/673	105/7206	8.32378292361e-06
ko05031	Amphetamine addiction	22/673	91/7206	2.23081967133e-05
ko04742	Taste transduction	17/673	61/7206	2.69650195445e-05
ko04072	Phospholipase D signaling pathway	37/673	197/7206	2.99422316621e-05
ko04966	Collecting duct acid secretion	10/673	26/7206	6.27193558839e-05
ko04360	Axon guidance	41/673	233/7206	7.65956670789e-05
ko04972	Pancreatic secretion	24/673	111/7206	8.54452517632e-05
ko04070	Phosphatidylinositol signaling system	24/673	112/7206	9.49505927993e-05
ko04710	Circadian rhythm	13/673	43/7206	9.51274292693e-05
ko04010	MAPK signaling pathway	51/673	321/7206	0.000117006096572
ko04120	Ubiquitin mediated proteolysis	2/673	138/7206	0.000289781698769
ko04750	Inflammatory mediator regulation of TRP channels	24/673	122/7206	0.000397000069974
ko03013	RNA transport	4/673	166/7206	0.000626633240652
ko04141	Protein processing in endoplasmic reticulum	5/673	184/7206	0.000710057517152
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/673	14/7206	0.00101169407247
ko04976	Bile secretion	17/673	80/7206	0.0013169038197
ko05231	Choline metabolism in cancer	24/673	134/7206	0.00149317190678
ko05110	Vibrio cholerae infection	14/673	63/7206	0.00165512385868
ko04924	Renin secretion	17/673	86/7206	0.00238079017055
ko04918	Thyroid hormone synthesis	17/673	86/7206	0.00238079017055
ko04720	Long-term potentiation	19/673	99/7206	0.00240839386268
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/673	59/7206	0.00259926439466
ko05016	Huntington's disease	8/673	215/7206	0.00264795562233
ko04014	Ras signaling pathway	41/673	279/7206	0.00311013994929
ko04964	Proximal tubule bicarbonate reclamation	8/673	29/7206	0.00403929438436
ko04923	Regulation of lipolysis in adipocytes	15/673	77/7206	0.00498136413814
ko05164	Influenza A	6/673	167/7206	0.00667285962409
ko04745	Phototransduction - fly	9/673	38/7206	0.00702765674574
ko04015	Rap1 signaling pathway	39/673	278/7206	0.00846645195463
ko04540	Gap junction	21/673	128/7206	0.00888311161927
ko04612	Antigen processing and presentation	1/673	77/7206	0.00903075021487
ko04110	Cell cycle	5/673	145/7206	0.00914539528023
ko04270	Vascular smooth muscle contraction	24/673	154/7206	0.0111394724949
ko04666	Fc gamma R-mediated phagocytosis	20/673	122/7206	0.0112999829297
ko04960	Aldosterone-regulated sodium reabsorption	9/673	41/7206	0.0117407163811
ko00240	Pyrimidine metabolism	3/673	110/7206	0.012171602353
ko04071	Sphingolipid signaling pathway	25/673	162/7206	0.0129453495663
ko04915	Estrogen signaling pathway	21/673	131/7206	0.0140602309389
ko04930	Type II diabetes mellitus	11/673	54/7206	0.014917536786
ko04744	Phototransduction	8/673	36/7206	0.0159178620212
ko05120	Epithelial cell signaling in Helicobacter pylori infection	16/673	92/7206	0.0168634758973
ko04916	Melanogenesis	22/673	142/7206	0.0184151733607
ko05203	Viral carcinogenesis	15/673	277/7206	0.0201298289869
ko04922	Glucagon signaling pathway	20/673	128/7206	0.0203216584975
ko05169	Epstein-Barr virus infection	10/673	206/7206	0.0208206310096
ko05030	Cocaine addiction	13/673	73/7206	0.0229665923942
ko04350	TGF-beta signaling pathway	3/673	103/7206	0.0244189372207
ko05224	Breast cancer	8/673	174/7206	0.0248949188534
ko04912	GnRH signaling pathway	19/673	122/7206	0.0262435299819
ko04711	Circadian rhythm - fly	4/673	13/7206	0.0271941366245
ko00680	Methane metabolism	7/673	34/7206	0.0347230194336
ko05168	Herpes simplex infection	9/673	182/7206	0.0382672589343
ko00330	Arginine and proline metabolism	1/673	61/7206	0.042168924601
ko05323	Rheumatoid arthritis	14/673	89/7206	0.0436071865221
ko00562	Inositol phosphate metabolism	14/673	89/7206	0.0436071865221
ko04115	p53 signaling pathway	2/673	74/7206	0.0441806649283
ko04514	Cell adhesion molecules (CAMs)	19/673	130/7206	0.0464903260602
ko04730	Long-term depression	13/673	78/7206	0.0465470917984