ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	85/722	145/7206	1.46356166539e-48
ko03460	Fanconi anemia pathway	36/722	51/7206	3.54690025471e-25
ko03013	RNA transport	65/722	166/7206	5.79701102962e-24
ko03440	Homologous recombination	31/722	41/7206	2.48139579938e-23
ko04110	Cell cycle	58/722	145/7206	5.03732955971e-22
ko03030	DNA replication	28/722	38/7206	1.16168808132e-20
ko04111	Cell cycle - yeast	43/722	90/7206	3.36211347679e-20
ko03008	Ribosome biogenesis in eukaryotes	39/722	79/7206	4.54706474162e-19
ko03430	Mismatch repair	18/722	22/7206	4.23361042426e-15
ko03420	Nucleotide excision repair	25/722	46/7206	6.38149427466e-14
ko04113	Meiosis - yeast	31/722	70/7206	9.21623390947e-14
ko04020	Calcium signaling pathway	1/722	265/7206	2.10087534319e-11
ko03018	RNA degradation	31/722	84/7206	3.08460466884e-11
ko03022	Basal transcription factors	21/722	44/7206	1.70294267578e-10
ko05322	Systemic lupus erythematosus	42/722	151/7206	3.66470190349e-10
ko00240	Pyrimidine metabolism	34/722	110/7206	8.74313127872e-10
ko03410	Base excision repair	18/722	38/7206	4.10489491703e-09
ko04144	Endocytosis	8/722	342/7206	2.95549351017e-08
ko04060	Cytokine-cytokine receptor interaction	1/722	191/7206	5.64006083726e-08
ko04024	cAMP signaling pathway	6/722	279/7206	3.68564196031e-07
ko04022	cGMP-PKG signaling pathway	3/722	216/7206	4.20162267701e-07
ko05203	Viral carcinogenesis	54/722	277/7206	1.10673350532e-06
ko03020	RNA polymerase	13/722	29/7206	1.36551682421e-06
ko04510	Focal adhesion	5/722	240/7206	1.71608013275e-06
ko03015	mRNA surveillance pathway	25/722	93/7206	2.79536801775e-06
ko04151	PI3K-Akt signaling pathway	15/722	390/7206	5.2171546015e-06
ko04015	Rap1 signaling pathway	8/722	278/7206	5.66393321569e-06
ko04261	Adrenergic signaling in cardiomyocytes	4/722	205/7206	8.4177745055e-06
ko05010	Alzheimer's disease	4/722	202/7206	1.24813446377e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/722	182/7206	1.35393975662e-05
ko04120	Ubiquitin mediated proteolysis	31/722	138/7206	1.81038046259e-05
ko04723	Retrograde endocannabinoid signaling	3/722	175/7206	1.87402935702e-05
ko04810	Regulation of actin cytoskeleton	8/722	264/7206	2.24490245023e-05
ko05034	Alcoholism	45/722	238/7206	2.27312194816e-05
ko04724	Glutamatergic synapse	2/722	152/7206	2.77676800631e-05
ko04270	Vascular smooth muscle contraction	2/722	154/7206	2.94366728902e-05
ko04921	Oxytocin signaling pathway	5/722	209/7206	3.11170135492e-05
ko03450	Non-homologous end-joining	8/722	15/7206	3.31476608591e-05
ko01200	Carbon metabolism	1/722	128/7206	3.67280017639e-05
ko04014	Ras signaling pathway	10/722	279/7206	6.26241880848e-05
ko04621	NOD-like receptor signaling pathway	3/722	157/7206	0.000122825092299
ko04713	Circadian entrainment	2/722	136/7206	0.00012821507899
ko04514	Cell adhesion molecules (CAMs)	2/722	130/7206	0.000185641603095
ko04360	Axon guidance	8/722	233/7206	0.000214244254389
ko04728	Dopaminergic synapse	5/722	185/7206	0.000254761727037
ko00190	Oxidative phosphorylation	2/722	127/7206	0.000270367167343
ko04750	Inflammatory mediator regulation of TRP channels	2/722	122/7206	0.000393915584053
ko04725	Cholinergic synapse	4/722	160/7206	0.000433473897524
ko04971	Gastric acid secretion	1/722	98/7206	0.000571619173773
ko05012	Parkinson's disease	4/722	155/7206	0.000605391669643
ko04380	Osteoclast differentiation	3/722	134/7206	0.00072854042567
ko04062	Chemokine signaling pathway	7/722	201/7206	0.000744470638754
ko04931	Insulin resistance	3/722	137/7206	0.00075825074406
ko04974	Protein digestion and absorption	1/722	96/7206	0.000863287063285
ko05166	HTLV-I infection	47/722	292/7206	0.000939360587324
ko04072	Phospholipase D signaling pathway	7/722	197/7206	0.00102271976549
ko04915	Estrogen signaling pathway	3/722	131/7206	0.00104471140164
ko04010	MAPK signaling pathway	16/722	321/7206	0.00116308079984
ko04727	GABAergic synapse	2/722	110/7206	0.00120351267756
ko04972	Pancreatic secretion	2/722	111/7206	0.0012061606935
ko05031	Amphetamine addiction	1/722	91/7206	0.00125426949778
ko04152	AMPK signaling pathway	5/722	161/7206	0.00130098956543
ko05145	Toxoplasmosis	3/722	126/7206	0.0014821150054
ko04114	Oocyte meiosis	26/722	139/7206	0.00148914207499
ko04659	Th17 cell differentiation	2/722	106/7206	0.00174045445508
ko04920	Adipocytokine signaling pathway	1/722	89/7206	0.00194090287654
ko04666	Fc gamma R-mediated phagocytosis	3/722	122/7206	0.0021075232533
ko04726	Serotonergic synapse	4/722	137/7206	0.00235566155049
ko05205	Proteoglycans in cancer	13/722	271/7206	0.00257687272584
ko01230	Biosynthesis of amino acids	1/722	85/7206	0.00286111613251
ko04218	Cellular senescence	30/722	177/7206	0.003392775254
ko04611	Platelet activation	6/722	163/7206	0.0035067224095
ko04620	Toll-like receptor signaling pathway	2/722	100/7206	0.00369380456932
ko04512	ECM-receptor interaction	1/722	79/7206	0.00402260095096
ko04740	Olfactory transduction	1/722	80/7206	0.00409121599745
ko05202	Transcriptional misregulation in cancer	31/722	188/7206	0.00451524479485
ko05142	Chagas disease (American trypanosomiasis)	4/722	130/7206	0.00461870159309
ko04371	Apelin signaling pathway	7/722	177/7206	0.00482357137531
ko04658	Th1 and Th2 cell differentiation	2/722	96/7206	0.00531936694903
ko00010	Glycolysis / Gluconeogenesis	1/722	74/7206	0.00588965865189
ko05134	Legionellosis	1/722	74/7206	0.00588965865189
ko05140	Leishmaniasis	1/722	75/7206	0.00591720707026
ko05032	Morphine addiction	3/722	110/7206	0.00597819825366
ko05152	Tuberculosis	8/722	187/7206	0.00615298883049
ko04923	Regulation of lipolysis in adipocytes	1/722	77/7206	0.00619524374654
ko05200	Pathways in cancer	32/722	492/7206	0.00631323588866
ko04660	T cell receptor signaling pathway	4/722	124/7206	0.00638611047157
ko04922	Glucagon signaling pathway	4/722	128/7206	0.00666953630436
ko04914	Progesterone-mediated oocyte maturation	19/722	104/7206	0.00809820918498
ko04925	Aldosterone synthesis and secretion	3/722	105/7206	0.0083949882876
ko04670	Leukocyte transendothelial migration	6/722	151/7206	0.0088016132883
ko04668	TNF signaling pathway	4/722	120/7206	0.00884241379311
ko04912	GnRH signaling pathway	4/722	122/7206	0.00893208126551
ko04066	HIF-1 signaling pathway	4/722	123/7206	0.00907209495148
ko05030	Cocaine addiction	1/722	73/7206	0.00909846893856
ko04924	Renin secretion	2/722	86/7206	0.0106858762273
ko05133	Pertussis	2/722	87/7206	0.0107711196492
ko04146	Peroxisome	2/722	89/7206	0.0112486137745
ko05168	Herpes simplex infection	29/722	182/7206	0.0116776950345
ko04520	Adherens junction	3/722	103/7206	0.0119739449821
ko04630	Jak-STAT signaling pathway	5/722	132/7206	0.0122170101773
ko05418	Fluid shear stress and atherosclerosis	8/722	173/7206	0.0142319522653
ko04650	Natural killer cell mediated cytotoxicity	3/722	97/7206	0.0164698637185
ko05100	Bacterial invasion of epithelial cells	3/722	99/7206	0.0167859560436
ko04115	p53 signaling pathway	14/722	74/7206	0.0175747377212
ko04721	Synaptic vesicle cycle	2/722	80/7206	0.0223463600608
ko04530	Tight junction	13/722	228/7206	0.0246926169739
ko04962	Vasopressin-regulated water reabsorption	1/722	58/7206	0.0270962862324
ko05231	Choline metabolism in cancer	6/722	134/7206	0.028526405976
ko04742	Taste transduction	1/722	61/7206	0.0285505898761
ko04933	AGE-RAGE signaling pathway in diabetic complications	6/722	135/7206	0.0287226813356
ko05162	Measles	5/722	120/7206	0.0304549358922
ko04662	B cell receptor signaling pathway	3/722	88/7206	0.0318546250462
ko05323	Rheumatoid arthritis	3/722	89/7206	0.0319059077534
ko00520	Amino sugar and nucleotide sugar metabolism	1/722	55/7206	0.0398156235137
ko04720	Long-term potentiation	4/722	99/7206	0.0427529100624
ko04918	Thyroid hormone synthesis	3/722	86/7206	0.0445857721343
ko04916	Melanogenesis	7/722	142/7206	0.0464350286294
ko05016	Huntington's disease	13/722	215/7206	0.0494838461577