ko pathway ratio_in_study ratio_in_pop p_value ko05224 Breast cancer 26/215 174/7206 6.47934832192e-12 ko05217 Basal cell carcinoma 16/215 68/7206 8.41983429411e-11 ko04330 Notch signaling pathway 15/215 62/7206 2.18600142516e-10 ko05205 Proteoglycans in cancer 28/215 271/7206 6.42037229399e-09 ko04390 Hippo signaling pathway 23/215 188/7206 6.54892552359e-09 ko04550 Signaling pathways regulating pluripotency of stem cells 20/215 165/7206 7.87572768788e-08 ko05200 Pathways in cancer 34/215 492/7206 3.10077105107e-06 ko04340 Hedgehog signaling pathway 10/215 58/7206 6.75809888338e-06 ko04360 Axon guidance 20/215 233/7206 1.85911242412e-05 ko04310 Wnt signaling pathway 16/215 181/7206 9.24499086757e-05 ko05418 Fluid shear stress and atherosclerosis 15/215 173/7206 0.000190452407721 ko04916 Melanogenesis 13/215 142/7206 0.000300623876715 ko01522 Endocrine resistance 12/215 124/7206 0.000307241947348 ko04080 Neuroactive ligand-receptor interaction 2/215 423/7206 0.000335292544063 ko04612 Antigen processing and presentation 9/215 77/7206 0.000439109274761 ko04658 Th1 and Th2 cell differentiation 10/215 96/7206 0.000543738366769 ko04350 TGF-beta signaling pathway 10/215 103/7206 0.000948617283439 ko05130 Pathogenic Escherichia coli infection 8/215 77/7206 0.00197683204014 ko05166 HTLV-I infection 18/215 292/7206 0.00393395013579 ko04391 Hippo signaling pathway - fly 8/215 90/7206 0.00523671765047 ko04145 Phagosome 11/215 162/7206 0.00895301772804 ko04950 Maturity onset diabetes of the young 4/215 29/7206 0.0101914479859 ko00514 Other types of O-glycan biosynthesis 4/215 30/7206 0.0114903271974 ko04150 mTOR signaling pathway 12/215 184/7206 0.0123286556318 ko04392 Hippo signaling pathway -multiple species 4/215 31/7206 0.0128910911189 ko04514 Cell adhesion molecules (CAMs) 9/215 130/7206 0.0154477027936 ko05323 Rheumatoid arthritis 7/215 89/7206 0.0166359079962 ko05222 Small cell lung cancer 7/215 89/7206 0.0166359079962 ko05215 Prostate cancer 8/215 111/7206 0.0175700483761 ko04011 MAPK signaling pathway - yeast 5/215 53/7206 0.020275144137 ko05206 MicroRNAs in cancer 11/215 177/7206 0.0209917750916 ko04962 Vasopressin-regulated water reabsorption 5/215 58/7206 0.028751236026 ko04151 PI3K-Akt signaling pathway 19/215 390/7206 0.0312209153657 ko05010 Alzheimer's disease 1/215 202/7206 0.0323999590099 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/215 182/7206 0.0453535996087 ko04015 Rap1 signaling pathway 14/215 278/7206 0.0472594670648