ko pathway ratio_in_study ratio_in_pop p_value ko05100 Bacterial invasion of epithelial cells 11/99 99/7206 8.69328608383e-08 ko05152 Tuberculosis 13/99 187/7206 1.40016066776e-06 ko05131 Shigellosis 9/99 82/7206 1.54536640446e-06 ko05132 Salmonella infection 9/99 98/7206 6.92380250068e-06 ko04810 Regulation of actin cytoskeleton 14/99 264/7206 1.2948460204e-05 ko04217 Necroptosis 11/99 178/7206 2.92725181068e-05 ko04621 NOD-like receptor signaling pathway 10/99 157/7206 5.33546438968e-05 ko05130 Pathogenic Escherichia coli infection 7/99 77/7206 8.1781891672e-05 ko00512 Mucin type O-glycan biosynthesis 4/99 29/7206 0.000611587873324 ko00520 Amino sugar and nucleotide sugar metabolism 5/99 55/7206 0.000893100893626 ko05133 Pertussis 6/99 87/7206 0.00118892887531 ko04666 Fc gamma R-mediated phagocytosis 7/99 122/7206 0.00137838962221 ko04071 Sphingolipid signaling pathway 8/99 162/7206 0.00165852051823 ko04611 Platelet activation 8/99 163/7206 0.00172465946397 ko05146 Amoebiasis 6/99 99/7206 0.00231200327925 ko04144 Endocytosis 12/99 342/7206 0.00239745810034 ko04210 Apoptosis 8/99 180/7206 0.00320519822522 ko01521 EGFR tyrosine kinase inhibitor resistance 6/99 106/7206 0.0032594337587 ko05014 Amyotrophic lateral sclerosis (ALS) 5/99 74/7206 0.00336877271777 ko04215 Apoptosis - multiple species 4/99 47/7206 0.0038030618241 ko04670 Leukocyte transendothelial migration 7/99 151/7206 0.00459741247018 ko04270 Vascular smooth muscle contraction 7/99 154/7206 0.00511772212966 ko04668 TNF signaling pathway 6/99 120/7206 0.00598661020015 ko04722 Neurotrophin signaling pathway 7/99 160/7206 0.00629020573035 ko05210 Colorectal cancer 5/99 86/7206 0.0064016522753 ko04750 Inflammatory mediator regulation of TRP channels 6/99 122/7206 0.00648137258441 ko04660 T cell receptor signaling pathway 6/99 124/7206 0.0070052928464 ko01522 Endocrine resistance 6/99 124/7206 0.0070052928464 ko04921 Oxytocin signaling pathway 8/99 209/7206 0.00782597392466 ko04068 FoxO signaling pathway 7/99 167/7206 0.00789986644303 ko05142 Chagas disease (American trypanosomiasis) 6/99 130/7206 0.0087614769349 ko04650 Natural killer cell mediated cytotoxicity 5/99 97/7206 0.0105290263939 ko04726 Serotonergic synapse 6/99 137/7206 0.0111865359128 ko04530 Tight junction 8/99 228/7206 0.0128440578997 ko05167 Kaposi's sarcoma-associated herpesvirus infection 7/99 191/7206 0.0157645383075 ko04012 ErbB signaling pathway 5/99 109/7206 0.0167911239176 ko04510 Focal adhesion 8/99 240/7206 0.0170438578136 ko04072 Phospholipase D signaling pathway 7/99 197/7206 0.01838524825 ko04623 Cytosolic DNA-sensing pathway 3/99 41/7206 0.0183864405672 ko05160 Hepatitis C 6/99 153/7206 0.0184490163825 ko05134 Legionellosis 4/99 74/7206 0.0185318590564 ko04115 p53 signaling pathway 4/99 74/7206 0.0185318590564 ko00051 Fructose and mannose metabolism 3/99 42/7206 0.0196073469567 ko01524 Platinum drug resistance 4/99 76/7206 0.02024104113 ko04730 Long-term depression 4/99 78/7206 0.022044552668 ko04130 SNARE interactions in vesicular transport 3/99 44/7206 0.0221808118444 ko05214 Glioma 4/99 79/7206 0.0229820584452 ko05200 Pathways in cancer 13/99 492/7206 0.0238502188658 ko04211 Longevity regulating pathway 5/99 123/7206 0.0267577205785 ko05164 Influenza A 6/99 167/7206 0.0270274774684 ko04910 Insulin signaling pathway 6/99 172/7206 0.0306427577465 ko04657 IL-17 signaling pathway 4/99 87/7206 0.0313563249946 ko04662 B cell receptor signaling pathway 4/99 88/7206 0.0325138514653 ko05120 Epithelial cell signaling in Helicobacter pylori infection 4/99 92/7206 0.0373930438927 ko04932 Non-alcoholic fatty liver disease (NAFLD) 6/99 182/7206 0.0387953422679 ko00261 Monobactam biosynthesis 1/99 3/7206 0.0406575682066 ko04010 MAPK signaling pathway 9/99 321/7206 0.0423944262153 ko05211 Renal cell carcinoma 4/99 96/7206 0.042672468237 ko00515 Mannose type O-glycan biosynthesis 2/99 25/7206 0.0456695330436