ko pathway ratio_in_study ratio_in_pop p_value ko03008 Ribosome biogenesis in eukaryotes 31/131 79/7206 1.13766961824e-34 ko04110 Cell cycle 17/131 145/7206 7.50184284903e-10 ko03030 DNA replication 10/131 38/7206 8.56772386423e-10 ko03040 Spliceosome 11/131 145/7206 6.01592477407e-05 ko04218 Cellular senescence 12/131 177/7206 8.28746316794e-05 ko00240 Pyrimidine metabolism 9/131 110/7206 0.000162324252081 ko00270 Cysteine and methionine metabolism 5/131 47/7206 0.00152977022265 ko03020 RNA polymerase 4/131 29/7206 0.00174161009229 ko03460 Fanconi anemia pathway 5/131 51/7206 0.00221091562651 ko03410 Base excision repair 4/131 38/7206 0.00477211744796 ko05222 Small cell lung cancer 6/131 89/7206 0.0054543603511 ko04111 Cell cycle - yeast 6/131 90/7206 0.00575873095911 ko03430 Mismatch repair 3/131 22/7206 0.0070229349248 ko04113 Meiosis - yeast 5/131 70/7206 0.00866353801982 ko03013 RNA transport 8/131 166/7206 0.0105396457387 ko04115 p53 signaling pathway 5/131 74/7206 0.010888183467 ko05219 Bladder cancer 4/131 48/7206 0.0109449014653 ko05206 MicroRNAs in cancer 8/131 177/7206 0.0150940502509 ko05212 Pancreatic cancer 5/131 83/7206 0.0172551603065 ko05168 Herpes simplex infection 8/131 182/7206 0.0175802350818 ko00230 Purine metabolism 8/131 194/7206 0.0247305571689 ko01522 Endocrine resistance 6/131 124/7206 0.0251333513456 ko03450 Non-homologous end-joining 2/131 15/7206 0.0295021382673 ko05223 Non-small cell lung cancer 4/131 66/7206 0.0316212919561 ko05161 Hepatitis B 7/131 173/7206 0.0378850027488 ko03440 Homologous recombination 3/131 41/7206 0.0379004689402