ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	174/981	423/7206	6.54986145362e-48
ko04724	Glutamatergic synapse	79/981	152/7206	4.29470492537e-30
ko05033	Nicotine addiction	43/981	56/7206	8.18106568697e-27
ko05032	Morphine addiction	58/981	110/7206	9.41109337162e-23
ko04728	Dopaminergic synapse	78/981	185/7206	3.08444450137e-22
ko04727	GABAergic synapse	55/981	110/7206	3.34757416564e-20
ko04713	Circadian entrainment	62/981	136/7206	5.55729368356e-20
ko04725	Cholinergic synapse	67/981	160/7206	4.81818018653e-19
ko04721	Synaptic vesicle cycle	43/981	80/7206	1.38648989242e-17
ko04024	cAMP signaling pathway	92/981	279/7206	2.30055769419e-17
ko04723	Retrograde endocannabinoid signaling	67/981	175/7206	1.29957882538e-16
ko04726	Serotonergic synapse	56/981	137/7206	1.53544824612e-15
ko04020	Calcium signaling pathway	85/981	265/7206	2.86026521161e-15
ko04911	Insulin secretion	48/981	117/7206	1.44380542712e-13
ko04921	Oxytocin signaling pathway	68/981	209/7206	8.87817828021e-13
ko04742	Taste transduction	31/981	61/7206	3.56626284063e-12
ko05031	Amphetamine addiction	39/981	91/7206	5.65501991133e-12
ko04261	Adrenergic signaling in cardiomyocytes	62/981	205/7206	3.17400011872e-10
ko04720	Long-term potentiation	38/981	99/7206	5.34012376882e-10
ko04744	Phototransduction	20/981	36/7206	3.35025133219e-09
ko03040	Spliceosome	1/981	145/7206	2.32428347478e-08
ko04970	Salivary secretion	34/981	95/7206	3.47181395513e-08
ko05030	Cocaine addiction	27/981	73/7206	4.17513761119e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	27/981	74/7206	5.73539951096e-07
ko04925	Aldosterone synthesis and secretion	34/981	105/7206	7.39210982412e-07
ko04070	Phosphatidylinositol signaling system	35/981	112/7206	1.04167000234e-06
ko04360	Axon guidance	59/981	233/7206	1.30769087343e-06
ko04010	MAPK signaling pathway	75/981	321/7206	1.57102448382e-06
ko04514	Cell adhesion molecules (CAMs)	38/981	130/7206	3.23205636093e-06
ko04971	Gastric acid secretion	31/981	98/7206	3.57010676721e-06
ko05322	Systemic lupus erythematosus	4/981	151/7206	5.95032157682e-06
ko05203	Viral carcinogenesis	15/981	277/7206	9.99955559592e-06
ko04745	Phototransduction - fly	16/981	38/7206	1.44712010264e-05
ko05168	Herpes simplex infection	7/981	182/7206	1.4809021591e-05
ko04120	Ubiquitin mediated proteolysis	4/981	138/7206	2.63728474392e-05
ko03013	RNA transport	6/981	166/7206	2.72488983444e-05
ko04022	cGMP-PKG signaling pathway	51/981	216/7206	4.86811054861e-05
ko04966	Collecting duct acid secretion	12/981	26/7206	5.8121617316e-05
ko04972	Pancreatic secretion	31/981	111/7206	6.26506029981e-05
ko04730	Long-term depression	24/981	78/7206	7.50761477684e-05
ko04621	NOD-like receptor signaling pathway	6/981	157/7206	7.84865168583e-05
ko04740	Olfactory transduction	24/981	80/7206	0.00010903896333
ko04014	Ras signaling pathway	61/981	279/7206	0.000115243787959
ko04750	Inflammatory mediator regulation of TRP channels	32/981	122/7206	0.000160716378144
ko04141	Protein processing in endoplasmic reticulum	9/981	184/7206	0.000177158950426
ko04964	Proximal tubule bicarbonate reclamation	12/981	29/7206	0.00021082647969
ko04060	Cytokine-cytokine receptor interaction	10/981	191/7206	0.000238771302871
ko04260	Cardiac muscle contraction	27/981	98/7206	0.000263530606461
ko04612	Antigen processing and presentation	1/981	77/7206	0.000310297393855
ko04072	Phospholipase D signaling pathway	45/981	197/7206	0.000315005966691
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/981	79/7206	0.000352161323566
ko05164	Influenza A	9/981	167/7206	0.00083248463091
ko04540	Gap junction	31/981	128/7206	0.00101704038277
ko04924	Renin secretion	23/981	86/7206	0.0012145062247
ko04626	Plant-pathogen interaction	8/981	18/7206	0.00141472354082
ko03008	Ribosome biogenesis in eukaryotes	2/981	79/7206	0.00143885529586
ko05110	Vibrio cholerae infection	18/981	63/7206	0.00146322423001
ko04915	Estrogen signaling pathway	31/981	131/7206	0.00177152556125
ko04110	Cell cycle	8/981	145/7206	0.00213233989604
ko05414	Dilated cardiomyopathy	27/981	112/7206	0.00308853420006
ko04930	Type II diabetes mellitus	15/981	54/7206	0.00485426129346
ko04976	Bile secretion	20/981	80/7206	0.00507785785561
ko05161	Hepatitis B	12/981	173/7206	0.00692408764431
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/981	14/7206	0.00710206795089
ko04610	Complement and coagulation cascades	3/981	79/7206	0.00740214302976
ko00590	Arachidonic acid metabolism	1/981	52/7206	0.00748497738909
ko04146	Peroxisome	4/981	89/7206	0.00769685230195
ko05166	HTLV-I infection	25/981	292/7206	0.00877775564281
ko04960	Aldosterone-regulated sodium reabsorption	12/981	41/7206	0.00918887122551
ko05162	Measles	7/981	120/7206	0.0100971329406
ko05140	Leishmaniasis	3/981	75/7206	0.0103429768574
ko00240	Pyrimidine metabolism	6/981	110/7206	0.0107731548907
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/981	59/7206	0.0125627324527
ko05169	Epstein-Barr virus infection	16/981	206/7206	0.0128632489483
ko04330	Notch signaling pathway	2/981	62/7206	0.0138616194764
ko00310	Lysine degradation	3/981	73/7206	0.0148838660871
ko04064	NF-kappa B signaling pathway	5/981	96/7206	0.0152616950099
ko04015	Rap1 signaling pathway	52/981	278/7206	0.0156673060232
ko03420	Nucleotide excision repair	1/981	46/7206	0.016452584064
ko04923	Regulation of lipolysis in adipocytes	18/981	77/7206	0.0181658824396
ko05205	Proteoglycans in cancer	24/981	271/7206	0.0186422826199
ko00562	Inositol phosphate metabolism	20/981	89/7206	0.0191861474295
ko05231	Choline metabolism in cancer	28/981	134/7206	0.0210503437828
ko04973	Carbohydrate digestion and absorption	11/981	42/7206	0.0239069767809
ko03022	Basal transcription factors	1/981	44/7206	0.0247565631848
ko00071	Fatty acid degradation	1/981	45/7206	0.0257085669903
ko04722	Neurotrophin signaling pathway	32/981	160/7206	0.0258212445778
ko04071	Sphingolipid signaling pathway	32/981	162/7206	0.0270714511428
ko00280	Valine, leucine and isoleucine degradation	2/981	54/7206	0.0277294167669
ko00480	Glutathione metabolism	2/981	55/7206	0.027982923593
ko05214	Glioma	18/981	79/7206	0.0298609356107
ko05230	Central carbon metabolism in cancer	18/981	81/7206	0.0324626291109
ko04012	ErbB signaling pathway	23/981	109/7206	0.0332004063247
ko05145	Toxoplasmosis	9/981	126/7206	0.0348462695378
ko00980	Metabolism of xenobiotics by cytochrome P450	1/981	40/7206	0.0358957614164
ko03018	RNA degradation	5/981	84/7206	0.0369813013937
ko05410	Hypertrophic cardiomyopathy (HCM)	21/981	100/7206	0.0386086187906
ko04115	p53 signaling pathway	4/981	74/7206	0.0393083544508
ko04630	Jak-STAT signaling pathway	10/981	132/7206	0.0400601498299
ko04622	RIG-I-like receptor signaling pathway	3/981	62/7206	0.0401988324394
ko04640	Hematopoietic cell lineage	3/981	64/7206	0.0413274652639
ko04217	Necroptosis	15/981	178/7206	0.0454642743268
ko04062	Chemokine signaling pathway	37/981	201/7206	0.0476526956409