ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	162/925	423/7206	3.51861918779e-43
ko04724	Glutamatergic synapse	77/925	152/7206	3.87463730589e-30
ko05033	Nicotine addiction	44/925	56/7206	2.85992395361e-29
ko04727	GABAergic synapse	57/925	110/7206	3.49008959215e-23
ko05032	Morphine addiction	57/925	110/7206	3.49008959215e-23
ko04728	Dopaminergic synapse	77/925	185/7206	3.53447146607e-23
ko04713	Circadian entrainment	64/925	136/7206	6.31054162624e-23
ko04721	Synaptic vesicle cycle	46/925	80/7206	2.03455717316e-21
ko04723	Retrograde endocannabinoid signaling	69/925	175/7206	2.6709470585e-19
ko04024	cAMP signaling pathway	88/925	279/7206	7.07445080941e-17
ko04725	Cholinergic synapse	61/925	160/7206	2.35316128274e-16
ko04744	Phototransduction	25/925	36/7206	5.65842675282e-15
ko04020	Calcium signaling pathway	80/925	265/7206	3.0146074726e-14
ko04921	Oxytocin signaling pathway	68/925	209/7206	4.72214780862e-14
ko04911	Insulin secretion	47/925	117/7206	7.15704486464e-14
ko05031	Amphetamine addiction	38/925	91/7206	4.46962545581e-12
ko04742	Taste transduction	30/925	61/7206	5.11604947527e-12
ko04261	Adrenergic signaling in cardiomyocytes	63/925	205/7206	7.66997494078e-12
ko04720	Long-term potentiation	39/925	99/7206	2.04611083183e-11
ko04726	Serotonergic synapse	47/925	137/7206	5.56683856742e-11
ko03040	Spliceosome	1/925	145/7206	9.53798663092e-08
ko04970	Salivary secretion	32/925	95/7206	1.10608125364e-07
ko04925	Aldosterone synthesis and secretion	34/925	105/7206	1.3277940231e-07
ko05030	Cocaine addiction	26/925	73/7206	5.01497692419e-07
ko05203	Viral carcinogenesis	11/925	277/7206	5.31169359618e-07
ko03010	Ribosome	1/925	129/7206	7.37302051212e-07
ko04010	MAPK signaling pathway	71/925	321/7206	2.16354038569e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/925	74/7206	2.55143596596e-06
ko05164	Influenza A	4/925	167/7206	3.07694149816e-06
ko04514	Cell adhesion molecules (CAMs)	36/925	130/7206	4.25271077511e-06
ko04966	Collecting duct acid secretion	13/925	26/7206	4.90106972838e-06
ko04745	Phototransduction - fly	16/925	38/7206	6.72505179766e-06
ko04971	Gastric acid secretion	29/925	98/7206	9.70903593619e-06
ko04740	Olfactory transduction	25/925	80/7206	1.23099250962e-05
ko05322	Systemic lupus erythematosus	4/925	151/7206	1.99195997153e-05
ko04060	Cytokine-cytokine receptor interaction	7/925	191/7206	2.30011910002e-05
ko04022	cGMP-PKG signaling pathway	50/925	216/7206	2.76900142091e-05
ko05168	Herpes simplex infection	7/925	182/7206	4.44954020778e-05
ko04621	NOD-like receptor signaling pathway	5/925	157/7206	5.05980131693e-05
ko04260	Cardiac muscle contraction	27/925	98/7206	8.94283355601e-05
ko04730	Long-term depression	23/925	78/7206	9.65406210419e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/925	79/7206	0.000112208344682
ko05162	Measles	3/925	120/7206	0.000146637453991
ko04072	Phospholipase D signaling pathway	44/925	197/7206	0.000200250035845
ko05110	Vibrio cholerae infection	19/925	63/7206	0.000226805238772
ko04924	Renin secretion	24/925	86/7206	0.000233906960319
ko03013	RNA transport	7/925	166/7206	0.000237512971083
ko04120	Ubiquitin mediated proteolysis	5/925	138/7206	0.000420554811694
ko05169	Epstein-Barr virus infection	11/925	206/7206	0.000449221098004
ko04972	Pancreatic secretion	28/925	111/7206	0.00045675620607
ko05161	Hepatitis B	8/925	173/7206	0.000476674571623
ko04612	Antigen processing and presentation	1/925	77/7206	0.000478875375042
ko04110	Cell cycle	6/925	145/7206	0.000611807292689
ko05414	Dilated cardiomyopathy	27/925	112/7206	0.000907120676108
ko04070	Phosphatidylinositol signaling system	27/925	112/7206	0.000907120676108
ko04064	NF-kappa B signaling pathway	3/925	96/7206	0.00183488040212
ko05205	Proteoglycans in cancer	19/925	271/7206	0.00219634763603
ko04510	Focal adhesion	16/925	240/7206	0.00227122376627
ko05166	HTLV-I infection	21/925	292/7206	0.00228685033587
ko04014	Ras signaling pathway	53/925	279/7206	0.00330401475077
ko04610	Complement and coagulation cascades	2/925	79/7206	0.00332406731263
ko03008	Ribosome biogenesis in eukaryotes	2/925	79/7206	0.00332406731263
ko04141	Protein processing in endoplasmic reticulum	11/925	184/7206	0.00344361076344
ko04922	Glucagon signaling pathway	28/925	128/7206	0.00458318722303
ko04540	Gap junction	28/925	128/7206	0.00458318722303
ko05140	Leishmaniasis	2/925	75/7206	0.0046939780804
ko04626	Plant-pathogen interaction	7/925	18/7206	0.00494425335859
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/925	14/7206	0.00528873453855
ko04915	Estrogen signaling pathway	28/925	131/7206	0.00535009079334
ko04630	Jak-STAT signaling pathway	7/925	132/7206	0.00567008530562
ko05215	Prostate cancer	5/925	111/7206	0.00595358568798
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/925	92/7206	0.00704629322588
ko00520	Amino sugar and nucleotide sugar metabolism	1/925	55/7206	0.00773136098223
ko00480	Glutathione metabolism	1/925	55/7206	0.00773136098223
ko04750	Inflammatory mediator regulation of TRP channels	26/925	122/7206	0.00873987916243
ko04710	Circadian rhythm	12/925	43/7206	0.00904010283419
ko04210	Apoptosis	12/925	180/7206	0.0092816949699
ko05410	Hypertrophic cardiomyopathy (HCM)	22/925	100/7206	0.00973977453346
ko04350	TGF-beta signaling pathway	5/925	103/7206	0.0110639755682
ko04360	Axon guidance	43/925	233/7206	0.0124854737108
ko04550	Signaling pathways regulating pluripotency of stem cells	11/925	165/7206	0.0132322919142
ko04146	Peroxisome	4/925	89/7206	0.0155500784112
ko05222	Small cell lung cancer	4/925	89/7206	0.0155500784112
ko05219	Bladder cancer	1/925	48/7206	0.0169254524898
ko05200	Pathways in cancer	46/925	492/7206	0.0173570869502
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/925	59/7206	0.0180544532512
ko04330	Notch signaling pathway	2/925	62/7206	0.0201953686584
ko04930	Type II diabetes mellitus	13/925	54/7206	0.0221007630061
ko05144	Malaria	1/925	45/7206	0.0249145496473
ko00071	Fatty acid degradation	1/925	45/7206	0.0249145496473
ko03420	Nucleotide excision repair	1/925	46/7206	0.0250412079542
ko04964	Proximal tubule bicarbonate reclamation	8/925	29/7206	0.0258512677702
ko04976	Bile secretion	17/925	80/7206	0.0289919772735
ko05034	Alcoholism	42/925	238/7206	0.0296781472901
ko04722	Neurotrophin signaling pathway	30/925	160/7206	0.0306516053347
ko04140	Autophagy - animal	12/925	164/7206	0.0328180454366
ko00680	Methane metabolism	9/925	34/7206	0.0334510358895
ko00010	Glycolysis / Gluconeogenesis	16/925	74/7206	0.0338586880584
ko03022	Basal transcription factors	1/925	44/7206	0.0379388674858
ko04668	TNF signaling pathway	8/925	120/7206	0.0388888050777
ko04371	Apelin signaling pathway	32/925	177/7206	0.0402079367265
ko05416	Viral myocarditis	2/925	55/7206	0.0408020728729
ko05321	Inflammatory bowel disease (IBD)	2/925	56/7206	0.0416802490619
ko05010	Alzheimer's disease	36/925	202/7206	0.0417343624329
ko05217	Basal cell carcinoma	3/925	68/7206	0.0423192204899
ko00240	Pyrimidine metabolism	7/925	110/7206	0.0430713940565