ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	173/1105	423/7206	1.24041391663e-39
ko04724	Glutamatergic synapse	87/1105	152/7206	2.67207929421e-33
ko05033	Nicotine addiction	48/1105	56/7206	1.37979332707e-31
ko05032	Morphine addiction	66/1105	110/7206	3.98754492922e-27
ko04727	GABAergic synapse	65/1105	110/7206	3.42307626581e-26
ko04713	Circadian entrainment	71/1105	136/7206	4.82294822373e-24
ko04728	Dopaminergic synapse	81/1105	185/7206	6.46698108975e-21
ko04723	Retrograde endocannabinoid signaling	77/1105	175/7206	4.3474126798e-20
ko04725	Cholinergic synapse	71/1105	160/7206	7.43883211119e-19
ko04744	Phototransduction	27/1105	36/7206	1.81047801721e-15
ko04024	cAMP signaling pathway	95/1105	279/7206	2.72627248755e-15
ko04726	Serotonergic synapse	58/1105	137/7206	1.70722439854e-14
ko04742	Taste transduction	35/1105	61/7206	4.11160801464e-14
ko04020	Calcium signaling pathway	89/1105	265/7206	4.6820380633e-14
ko04721	Synaptic vesicle cycle	40/1105	80/7206	2.96774803948e-13
ko04921	Oxytocin signaling pathway	74/1105	209/7206	3.20600945088e-13
ko04911	Insulin secretion	49/1105	117/7206	3.1475144803e-12
ko05031	Amphetamine addiction	39/1105	91/7206	2.32496429677e-10
ko04720	Long-term potentiation	41/1105	99/7206	2.89977362204e-10
ko03040	Spliceosome	2/1105	145/7206	1.63370162753e-08
ko04261	Adrenergic signaling in cardiomyocytes	63/1105	205/7206	1.74248610156e-08
ko03010	Ribosome	1/1105	129/7206	1.75327936611e-08
ko05030	Cocaine addiction	29/1105	73/7206	3.47855099193e-07
ko05322	Systemic lupus erythematosus	4/1105	151/7206	4.94181409018e-07
ko04970	Salivary secretion	34/1105	95/7206	7.74181551752e-07
ko04745	Phototransduction - fly	18/1105	38/7206	3.01329558799e-06
ko04925	Aldosterone synthesis and secretion	35/1105	105/7206	3.47483616735e-06
ko04740	Olfactory transduction	29/1105	80/7206	4.73016595615e-06
ko04971	Gastric acid secretion	33/1105	98/7206	5.87945312123e-06
ko05203	Viral carcinogenesis	18/1105	277/7206	7.92835641647e-06
ko03013	RNA transport	7/1105	166/7206	9.10860128278e-06
ko04010	MAPK signaling pathway	78/1105	321/7206	1.65130265068e-05
ko04070	Phosphatidylinositol signaling system	35/1105	112/7206	1.68578427901e-05
ko04730	Long-term depression	27/1105	78/7206	2.07262553031e-05
ko04072	Phospholipase D signaling pathway	53/1105	197/7206	2.08303778821e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1105	74/7206	2.37676924157e-05
ko04972	Pancreatic secretion	34/1105	111/7206	4.52165637201e-05
ko04022	cGMP-PKG signaling pathway	56/1105	216/7206	4.64382398776e-05
ko04060	Cytokine-cytokine receptor interaction	11/1105	191/7206	5.92897764449e-05
ko05168	Herpes simplex infection	10/1105	182/7206	6.01280796646e-05
ko04110	Cell cycle	7/1105	145/7206	0.000100711038834
ko04710	Circadian rhythm	17/1105	43/7206	0.000101049344804
ko04514	Cell adhesion molecules (CAMs)	37/1105	130/7206	0.000110504443256
ko05169	Epstein-Barr virus infection	14/1105	206/7206	0.000250867565208
ko04621	NOD-like receptor signaling pathway	9/1105	157/7206	0.000291095240056
ko04141	Protein processing in endoplasmic reticulum	12/1105	184/7206	0.000373399445563
ko03008	Ribosome biogenesis in eukaryotes	2/1105	79/7206	0.000411346700637
ko04612	Antigen processing and presentation	2/1105	77/7206	0.000625250015067
ko04014	Ras signaling pathway	64/1105	279/7206	0.000652113676326
ko05164	Influenza A	11/1105	167/7206	0.000701577753911
ko04120	Ubiquitin mediated proteolysis	8/1105	138/7206	0.0007553032725
ko04750	Inflammatory mediator regulation of TRP channels	33/1105	122/7206	0.000832329953261
ko04930	Type II diabetes mellitus	18/1105	54/7206	0.000877987770448
ko04924	Renin secretion	25/1105	86/7206	0.00125358856565
ko04260	Cardiac muscle contraction	27/1105	98/7206	0.0016674858594
ko05162	Measles	7/1105	120/7206	0.00197941753452
ko00520	Amino sugar and nucleotide sugar metabolism	1/1105	55/7206	0.00209222955135
ko04964	Proximal tubule bicarbonate reclamation	11/1105	29/7206	0.00252336969144
ko05161	Hepatitis B	13/1105	173/7206	0.00261803281342
ko04915	Estrogen signaling pathway	33/1105	131/7206	0.00303784062781
ko05140	Leishmaniasis	3/1105	75/7206	0.00330363215295
ko04966	Collecting duct acid secretion	10/1105	26/7206	0.00349724711623
ko04064	NF-kappa B signaling pathway	5/1105	96/7206	0.00384465595326
ko04360	Axon guidance	52/1105	233/7206	0.00401912063278
ko04922	Glucagon signaling pathway	32/1105	128/7206	0.00407019521853
ko04540	Gap junction	32/1105	128/7206	0.00407019521853
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/1105	79/7206	0.0041062256763
ko03420	Nucleotide excision repair	1/1105	46/7206	0.00693817041068
ko00240	Pyrimidine metabolism	7/1105	110/7206	0.00704616572205
ko05414	Dilated cardiomyopathy	28/1105	112/7206	0.00758275271535
ko05130	Pathogenic Escherichia coli infection	4/1105	77/7206	0.0101012192813
ko04630	Jak-STAT signaling pathway	10/1105	132/7206	0.0101026384148
ko05133	Pertussis	5/1105	87/7206	0.0101279530855
ko03022	Basal transcription factors	1/1105	44/7206	0.0104233602495
ko04371	Apelin signaling pathway	40/1105	177/7206	0.0107604446807
ko05144	Malaria	1/1105	45/7206	0.0107864582119
ko04976	Bile secretion	21/1105	80/7206	0.0114421440283
ko05205	Proteoglycans in cancer	27/1105	271/7206	0.0123803239287
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1105	14/7206	0.0127417759871
ko04626	Plant-pathogen interaction	7/1105	18/7206	0.0131949586828
ko05202	Transcriptional misregulation in cancer	17/1105	188/7206	0.0135436748836
ko05145	Toxoplasmosis	10/1105	126/7206	0.017429491361
ko00562	Inositol phosphate metabolism	22/1105	89/7206	0.0176351079606
ko00910	Nitrogen metabolism	7/1105	19/7206	0.0181857883122
ko04330	Notch signaling pathway	3/1105	62/7206	0.0197174982464
ko04622	RIG-I-like receptor signaling pathway	3/1105	62/7206	0.0197174982464
ko04214	Apoptosis - fly	4/1105	72/7206	0.0198736070851
ko05166	HTLV-I infection	31/1105	292/7206	0.0202565984229
ko05016	Huntington's disease	21/1105	215/7206	0.020740900088
ko03410	Base excision repair	1/1105	38/7206	0.0229695048666
ko05200	Pathways in cancer	58/1105	492/7206	0.0231982051501
ko05410	Hypertrophic cardiomyopathy (HCM)	24/1105	100/7206	0.0240519830886
ko04610	Complement and coagulation cascades	5/1105	79/7206	0.0263976746545
ko05217	Basal cell carcinoma	4/1105	68/7206	0.0270240433181
ko04973	Carbohydrate digestion and absorption	12/1105	42/7206	0.0283792905806
ko05231	Choline metabolism in cancer	30/1105	134/7206	0.0286479649914
ko04658	Th1 and Th2 cell differentiation	7/1105	96/7206	0.0309784354064
ko03018	RNA degradation	6/1105	84/7206	0.0328265362246
ko04923	Regulation of lipolysis in adipocytes	19/1105	77/7206	0.0366805895834
ko04711	Circadian rhythm - fly	5/1105	13/7206	0.0370788283998
ko00071	Fatty acid degradation	2/1105	45/7206	0.037769855912
ko05416	Viral myocarditis	3/1105	55/7206	0.0383297764689
ko05321	Inflammatory bowel disease (IBD)	3/1105	56/7206	0.0386650235017
ko00230	Purine metabolism	40/1105	194/7206	0.0431590063408
ko05131	Shigellosis	6/1105	82/7206	0.0440559209756
ko04213	Longevity regulating pathway - multiple species	20/1105	86/7206	0.0492022651013
ko04960	Aldosterone-regulated sodium reabsorption	11/1105	41/7206	0.0494667879984