ko pathway ratio_in_study ratio_in_pop p_value ko05410 Hypertrophic cardiomyopathy (HCM) 14/123 100/7206 1.082580698e-09 ko05414 Dilated cardiomyopathy 14/123 112/7206 4.95665763248e-09 ko04260 Cardiac muscle contraction 11/123 98/7206 7.30405304365e-07 ko01200 Carbon metabolism 12/123 128/7206 1.58825246595e-06 ko04261 Adrenergic signaling in cardiomyocytes 15/123 205/7206 1.8093104039e-06 ko04921 Oxytocin signaling pathway 14/123 209/7206 1.14221911082e-05 ko04022 cGMP-PKG signaling pathway 13/123 216/7206 7.33298566642e-05 ko04371 Apelin signaling pathway 11/123 177/7206 0.000203854376149 ko00010 Glycolysis / Gluconeogenesis 7/123 74/7206 0.000248248563175 ko00020 Citrate cycle (TCA cycle) 5/123 35/7206 0.00028768468165 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 7/123 79/7206 0.000372707936837 ko04020 Calcium signaling pathway 13/123 265/7206 0.000553164817219 ko00620 Pyruvate metabolism 5/123 46/7206 0.0010459100482 ko04270 Vascular smooth muscle contraction 9/123 154/7206 0.00121579926688 ko00680 Methane metabolism 4/123 34/7206 0.0025229285143 ko04978 Mineral absorption 4/123 40/7206 0.00459592953012 ko04970 Salivary secretion 6/123 95/7206 0.00552290271865 ko04922 Glucagon signaling pathway 7/123 128/7206 0.00611835539112 ko00710 Carbon fixation in photosynthetic organisms 3/123 27/7206 0.0105284020509 ko04610 Complement and coagulation cascades 5/123 79/7206 0.0110145648773 ko04964 Proximal tubule bicarbonate reclamation 3/123 29/7206 0.0128318761955 ko05416 Viral myocarditis 4/123 55/7206 0.0141068908623 ko01230 Biosynthesis of amino acids 5/123 85/7206 0.0147923613834 ko00030 Pentose phosphate pathway 3/123 32/7206 0.0167866480139 ko00640 Propanoate metabolism 3/123 34/7206 0.0197607443937 ko04152 AMPK signaling pathway 7/123 161/7206 0.0199491479035 ko04510 Focal adhesion 9/123 240/7206 0.0212269220253 ko04974 Protein digestion and absorption 5/123 96/7206 0.023799173512 ko04971 Gastric acid secretion 5/123 98/7206 0.0257467058263 ko00720 Carbon fixation pathways in prokaryotes 2/123 17/7206 0.033251025955 ko00660 C5-Branched dibasic acid metabolism 1/123 2/7206 0.0338491922942 ko00910 Nitrogen metabolism 2/123 19/7206 0.0408964469101 ko00230 Purine metabolism 7/123 194/7206 0.0477688019116