ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	121/787	423/7206	2.13410653959e-25
ko04724	Glutamatergic synapse	66/787	152/7206	3.18398650458e-25
ko05033	Nicotine addiction	37/787	56/7206	6.67306238592e-23
ko04728	Dopaminergic synapse	66/787	185/7206	1.31607135538e-19
ko04721	Synaptic vesicle cycle	40/787	80/7206	2.02469829198e-18
ko05032	Morphine addiction	47/787	110/7206	6.59684075077e-18
ko04727	GABAergic synapse	45/787	110/7206	2.55486182705e-16
ko04713	Circadian entrainment	49/787	136/7206	4.99777428105e-15
ko04723	Retrograde endocannabinoid signaling	55/787	175/7206	8.37660084837e-14
ko04725	Cholinergic synapse	50/787	160/7206	1.50295068351e-12
ko04024	cAMP signaling pathway	70/787	279/7206	1.06295893807e-11
ko04726	Serotonergic synapse	42/787	137/7206	1.91168810492e-10
ko04911	Insulin secretion	37/787	117/7206	8.89868950016e-10
ko04921	Oxytocin signaling pathway	51/787	209/7206	2.42808675488e-08
ko04744	Phototransduction	17/787	36/7206	4.3627894495e-08
ko05031	Amphetamine addiction	28/787	91/7206	1.94657765631e-07
ko04261	Adrenergic signaling in cardiomyocytes	47/787	205/7206	5.53782553283e-07
ko04720	Long-term potentiation	28/787	99/7206	1.32706833698e-06
ko05030	Cocaine addiction	23/787	73/7206	1.51659462767e-06
ko05203	Viral carcinogenesis	9/787	277/7206	2.94202082925e-06
ko04020	Calcium signaling pathway	54/787	265/7206	4.50106529055e-06
ko04010	MAPK signaling pathway	62/787	321/7206	5.58900951847e-06
ko03040	Spliceosome	2/787	145/7206	1.846046704e-05
ko04070	Phosphatidylinositol signaling system	28/787	112/7206	2.00062423002e-05
ko04120	Ubiquitin mediated proteolysis	2/787	138/7206	2.56352632312e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	21/787	74/7206	2.62788819345e-05
ko04966	Collecting duct acid secretion	11/787	26/7206	4.04750899618e-05
ko04972	Pancreatic secretion	27/787	111/7206	4.48884061136e-05
ko04514	Cell adhesion molecules (CAMs)	30/787	130/7206	5.19488994919e-05
ko04360	Axon guidance	46/787	233/7206	6.13784943461e-05
ko03013	RNA transport	4/787	166/7206	6.99366481689e-05
ko04964	Proximal tubule bicarbonate reclamation	11/787	29/7206	0.000133140830187
ko04970	Salivary secretion	23/787	95/7206	0.000182516515243
ko04742	Taste transduction	17/787	61/7206	0.000194228724123
ko05164	Influenza A	5/787	167/7206	0.00022974132903
ko05168	Herpes simplex infection	6/787	182/7206	0.000254306159939
ko05322	Systemic lupus erythematosus	4/787	151/7206	0.000291397580961
ko04730	Long-term depression	20/787	78/7206	0.000306537447409
ko04260	Cardiac muscle contraction	23/787	98/7206	0.00041873290521
ko04072	Phospholipase D signaling pathway	38/787	197/7206	0.000434336538161
ko04022	cGMP-PKG signaling pathway	40/787	216/7206	0.000781513808652
ko05205	Proteoglycans in cancer	14/787	271/7206	0.000999207350772
ko04060	Cytokine-cytokine receptor interaction	8/787	191/7206	0.00133848822454
ko04621	NOD-like receptor signaling pathway	6/787	157/7206	0.00179680854439
ko04014	Ras signaling pathway	47/787	279/7206	0.00226217631645
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/787	14/7206	0.00230893265779
ko04141	Protein processing in endoplasmic reticulum	8/787	184/7206	0.00248424030174
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/787	79/7206	0.00286398307698
ko05169	Epstein-Barr virus infection	10/787	206/7206	0.00298919902109
ko05110	Vibrio cholerae infection	14/787	63/7206	0.00761139684152
ko04064	NF-kappa B signaling pathway	3/787	96/7206	0.0081254813644
ko04640	Hematopoietic cell lineage	1/787	64/7206	0.00835902288955
ko00562	Inositol phosphate metabolism	18/787	89/7206	0.00912073670245
ko04610	Complement and coagulation cascades	2/787	79/7206	0.0103451463653
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/787	59/7206	0.0108718123907
ko04925	Aldosterone synthesis and secretion	20/787	105/7206	0.0111607612836
ko05162	Measles	5/787	120/7206	0.0118286034456
ko00330	Arginine and proline metabolism	1/787	61/7206	0.0122919949039
ko05166	HTLV-I infection	19/787	292/7206	0.0124007146633
ko05161	Hepatitis B	9/787	173/7206	0.012931210633
ko04971	Gastric acid secretion	19/787	98/7206	0.0129968723141
ko04540	Gap junction	23/787	128/7206	0.0144620945496
ko05140	Leishmaniasis	2/787	75/7206	0.0147922545021
ko04146	Peroxisome	3/787	89/7206	0.0159993733107
ko05231	Choline metabolism in cancer	24/787	134/7206	0.0162813321814
ko04071	Sphingolipid signaling pathway	27/787	162/7206	0.0217648818593
ko04915	Estrogen signaling pathway	23/787	131/7206	0.0223385569229
ko04670	Leukocyte transendothelial migration	8/787	151/7206	0.0240622102472
ko00280	Valine, leucine and isoleucine degradation	1/787	54/7206	0.0265359377859
ko00480	Glutathione metabolism	1/787	55/7206	0.0270201410781
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/787	92/7206	0.0272782080817
ko05010	Alzheimer's disease	32/787	202/7206	0.0290700827887
ko00240	Pyrimidine metabolism	5/787	110/7206	0.0297141435687
ko04110	Cell cycle	8/787	145/7206	0.0312706999265
ko04630	Jak-STAT signaling pathway	7/787	132/7206	0.0341391294464
ko04510	Focal adhesion	16/787	240/7206	0.0344609918337
ko04217	Necroptosis	11/787	178/7206	0.0382737110852
ko04626	Plant-pathogen interaction	5/787	18/7206	0.0392388553088
ko00590	Arachidonic acid metabolism	1/787	52/7206	0.0402998495449
ko04612	Antigen processing and presentation	3/787	77/7206	0.0430831229307
ko05034	Alcoholism	36/787	238/7206	0.043761039818
ko05414	Dilated cardiomyopathy	19/787	112/7206	0.046296097254