ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 26/581 68/7206 3.72728278575e-12 ko04550 Signaling pathways regulating pluripotency of stem cells 40/581 165/7206 1.21012618326e-10 ko05033 Nicotine addiction 19/581 56/7206 3.11878265122e-08 ko04360 Axon guidance 44/581 233/7206 6.0973514321e-08 ko04950 Maturity onset diabetes of the young 13/581 29/7206 1.08127803695e-07 ko05224 Breast cancer 34/581 174/7206 1.23403480506e-06 ko04340 Hedgehog signaling pathway 17/581 58/7206 1.75717020016e-06 ko04721 Synaptic vesicle cycle 20/581 80/7206 3.44816957455e-06 ko04391 Hippo signaling pathway - fly 21/581 90/7206 6.43831191583e-06 ko04390 Hippo signaling pathway 33/581 188/7206 1.61339895632e-05 ko04310 Wnt signaling pathway 32/581 181/7206 1.99084621271e-05 ko05202 Transcriptional misregulation in cancer 32/581 188/7206 5.38188465237e-05 ko05200 Pathways in cancer 63/581 492/7206 0.00020140710279 ko04611 Platelet activation 2/581 163/7206 0.00020969945856 ko01200 Carbon metabolism 1/581 128/7206 0.000435546212824 ko04728 Dopaminergic synapse 29/581 185/7206 0.000493587560484 ko04727 GABAergic synapse 20/581 110/7206 0.000520361203102 ko04060 Cytokine-cytokine receptor interaction 4/581 191/7206 0.000663982562065 ko05014 Amyotrophic lateral sclerosis (ALS) 15/581 74/7206 0.000685114473257 ko04514 Cell adhesion molecules (CAMs) 22/581 130/7206 0.000842848722092 ko05032 Morphine addiction 19/581 110/7206 0.00122833735508 ko04141 Protein processing in endoplasmic reticulum 4/581 184/7206 0.00135232151089 ko04330 Notch signaling pathway 12/581 62/7206 0.00345424256471 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 7/581 26/7206 0.0036199218061 ko04066 HIF-1 signaling pathway 2/581 123/7206 0.003950473087 ko04723 Retrograde endocannabinoid signaling 25/581 175/7206 0.00448388818233 ko03040 Spliceosome 3/581 145/7206 0.00478678381411 ko04120 Ubiquitin mediated proteolysis 3/581 138/7206 0.00650535199843 ko04145 Phagosome 23/581 162/7206 0.00772652829931 ko04010 MAPK signaling pathway 39/581 321/7206 0.00851965310046 ko04512 ECM-receptor interaction 13/581 79/7206 0.0111864966543 ko04974 Protein digestion and absorption 15/581 96/7206 0.0122691951839 ko04932 Non-alcoholic fatty liver disease (NAFLD) 6/581 182/7206 0.0125726802969 ko03013 RNA transport 5/581 166/7206 0.0131806410518 ko05213 Endometrial cancer 11/581 62/7206 0.015157394584 ko05216 Thyroid cancer 7/581 34/7206 0.0168833783243 ko04621 NOD-like receptor signaling pathway 5/581 157/7206 0.0174961455441 ko04080 Neuroactive ligand-receptor interaction 47/581 423/7206 0.0211968069436 ko00604 Glycosphingolipid biosynthesis - ganglio series 4/581 14/7206 0.0217958015336 ko05012 Parkinson's disease 5/581 155/7206 0.0239039269129 ko04961 Endocrine and other factor-regulated calcium reabsorption 10/581 59/7206 0.0252611941601 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 4/581 15/7206 0.0278725018698 ko05134 Legionellosis 1/581 74/7206 0.0290507357161 ko05205 Proteoglycans in cancer 32/581 271/7206 0.029712259706 ko04341 Hedgehog signaling pathway - fly 7/581 38/7206 0.0299928883841 ko03410 Base excision repair 7/581 38/7206 0.0299928883841 ko01524 Platinum drug resistance 1/581 76/7206 0.0302777853978 ko05130 Pathogenic Escherichia coli infection 12/581 77/7206 0.0311794087417 ko05203 Viral carcinogenesis 13/581 277/7206 0.032426037719 ko05322 Systemic lupus erythematosus 5/581 151/7206 0.0325501908027 ko04724 Glutamatergic synapse 20/581 152/7206 0.0330336415162 ko04151 PI3K-Akt signaling pathway 43/581 390/7206 0.0347251872708 ko05206 MicroRNAs in cancer 22/581 177/7206 0.0358881424468 ko05168 Herpes simplex infection 7/581 182/7206 0.0370423665385 ko04911 Insulin secretion 16/581 117/7206 0.0372725676157 ko04211 Longevity regulating pathway 4/581 123/7206 0.0446440458291 ko05030 Cocaine addiction 11/581 73/7206 0.0465996031257