ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 22/186 191/7206 2.92426574158e-09 ko04610 Complement and coagulation cascades 14/186 79/7206 1.02410865165e-08 ko05150 Staphylococcus aureus infection 9/186 36/7206 2.16212491674e-07 ko04380 Osteoclast differentiation 16/186 134/7206 2.88399183037e-07 ko05144 Malaria 8/186 45/7206 1.61238240528e-05 ko04611 Platelet activation 14/186 163/7206 7.44592475062e-05 ko04659 Th17 cell differentiation 11/186 106/7206 8.2870803578e-05 ko04510 Focal adhesion 17/186 240/7206 0.000143460156478 ko04512 ECM-receptor interaction 9/186 79/7206 0.000181611700423 ko04650 Natural killer cell mediated cytotoxicity 10/186 97/7206 0.00018495996166 ko04666 Fc gamma R-mediated phagocytosis 11/186 122/7206 0.000292329285824 ko04810 Regulation of actin cytoskeleton 17/186 264/7206 0.000444538919479 ko05166 HTLV-I infection 18/186 292/7206 0.000510123887777 ko05321 Inflammatory bowel disease (IBD) 7/186 56/7206 0.000542649337326 ko04630 Jak-STAT signaling pathway 11/186 132/7206 0.000576499497018 ko05340 Primary immunodeficiency 5/186 30/7206 0.000915359992125 ko05162 Measles 10/186 120/7206 0.00102304865689 ko05152 Tuberculosis 13/186 187/7206 0.00105057499921 ko04620 Toll-like receptor signaling pathway 9/186 100/7206 0.00105477170526 ko04660 T cell receptor signaling pathway 10/186 124/7206 0.00131600756149 ko04144 Endocytosis 19/186 342/7206 0.00136677313652 ko05418 Fluid shear stress and atherosclerosis 12/186 173/7206 0.00166294620123 ko05323 Rheumatoid arthritis 8/186 89/7206 0.00200928242823 ko04672 Intestinal immune network for IgA production 5/186 37/7206 0.00241970028876 ko04933 AGE-RAGE signaling pathway in diabetic complications 10/186 135/7206 0.0024883576667 ko04015 Rap1 signaling pathway 16/186 278/7206 0.00274298668007 ko05202 Transcriptional misregulation in cancer 12/186 188/7206 0.00332895497274 ko04072 Phospholipase D signaling pathway 12/186 197/7206 0.00485244247111 ko05161 Hepatitis B 11/186 173/7206 0.00502428085512 ko04640 Hematopoietic cell lineage 6/186 64/7206 0.0059108142249 ko04218 Cellular senescence 11/186 177/7206 0.00595566602278 ko05142 Chagas disease (American trypanosomiasis) 9/186 130/7206 0.00630864256833 ko04514 Cell adhesion molecules (CAMs) 9/186 130/7206 0.00630864256833 ko04662 B cell receptor signaling pathway 7/186 88/7206 0.00744452958614 ko04151 PI3K-Akt signaling pathway 19/186 390/7206 0.00748598039827 ko05164 Influenza A 10/186 167/7206 0.0110074717462 ko04658 Th1 and Th2 cell differentiation 7/186 96/7206 0.0117755142408 ko04670 Leukocyte transendothelial migration 9/186 151/7206 0.0159675401162 ko05145 Toxoplasmosis 8/186 126/7206 0.015990994939 ko05020 Prion diseases 4/186 40/7206 0.0190371545684 ko05212 Pancreatic cancer 6/186 83/7206 0.0199452346273 ko05133 Pertussis 6/186 87/7206 0.0245415387334 ko04974 Protein digestion and absorption 6/186 96/7206 0.0373444872443 ko05132 Salmonella infection 6/186 98/7206 0.0406762965526 ko05100 Bacterial invasion of epithelial cells 6/186 99/7206 0.0424106448474 ko05146 Amoebiasis 6/186 99/7206 0.0424106448474 ko05140 Leishmaniasis 5/186 75/7206 0.0438835348427 ko05130 Pathogenic Escherichia coli infection 5/186 77/7206 0.0482414585077 ko04612 Antigen processing and presentation 5/186 77/7206 0.0482414585077 ko04520 Adherens junction 6/186 103/7206 0.0498102322847