ko pathway ratio_in_study ratio_in_pop p_value ko04650 Natural killer cell mediated cytotoxicity 22/337 97/7206 3.87486424844e-10 ko04060 Cytokine-cytokine receptor interaction 31/337 191/7206 8.01513240187e-10 ko04380 Osteoclast differentiation 23/337 134/7206 4.59860708357e-08 ko05340 Primary immunodeficiency 11/337 30/7206 4.88599323457e-08 ko05321 Inflammatory bowel disease (IBD) 14/337 56/7206 1.77723201169e-07 ko05164 Influenza A 23/337 167/7206 2.6670525765e-06 ko04137 Mitophagy - animal 15/337 82/7206 4.69230554431e-06 ko05152 Tuberculosis 24/337 187/7206 5.69257884792e-06 ko04621 NOD-like receptor signaling pathway 21/337 157/7206 1.16265093186e-05 ko04610 Complement and coagulation cascades 14/337 79/7206 1.43011287284e-05 ko04660 T cell receptor signaling pathway 18/337 124/7206 1.5979328835e-05 ko04630 Jak-STAT signaling pathway 18/337 132/7206 3.79575225457e-05 ko05320 Autoimmune thyroid disease 8/337 29/7206 3.80958720515e-05 ko05330 Allograft rejection 7/337 24/7206 7.97902038021e-05 ko04659 Th17 cell differentiation 15/337 106/7206 0.000109790860519 ko05162 Measles 16/337 120/7206 0.000134104889509 ko05140 Leishmaniasis 12/337 75/7206 0.000164005074415 ko04612 Antigen processing and presentation 12/337 77/7206 0.000212088347118 ko05145 Toxoplasmosis 16/337 126/7206 0.000238824702885 ko04672 Intestinal immune network for IgA production 8/337 37/7206 0.000246837551298 ko05167 Kaposi's sarcoma-associated herpesvirus infection 21/337 191/7206 0.00030855463278 ko05168 Herpes simplex infection 20/337 182/7206 0.000451070252572 ko04658 Th1 and Th2 cell differentiation 13/337 96/7206 0.000485926470015 ko04670 Leukocyte transendothelial migration 17/337 151/7206 0.000647762807124 ko04620 Toll-like receptor signaling pathway 13/337 100/7206 0.000723239756436 ko04217 Necroptosis 19/337 178/7206 0.000797058941843 ko05144 Malaria 8/337 45/7206 0.000994116800732 ko05332 Graft-versus-host disease 5/337 18/7206 0.00112319927703 ko05150 Staphylococcus aureus infection 7/337 36/7206 0.00118552019209 ko04666 Fc gamma R-mediated phagocytosis 14/337 122/7206 0.00158986835019 ko04145 Phagosome 17/337 162/7206 0.00182170244036 ko04611 Platelet activation 17/337 163/7206 0.00190320301114 ko05133 Pertussis 11/337 87/7206 0.0022926634779 ko04640 Hematopoietic cell lineage 9/337 64/7206 0.00271920027945 ko04072 Phospholipase D signaling pathway 19/337 197/7206 0.00285164215477 ko04664 Fc epsilon RI signaling pathway 10/337 77/7206 0.00293865781204 ko04723 Retrograde endocannabinoid signaling 1/337 175/7206 0.00334015442578 ko05310 Asthma 4/337 17/7206 0.00688849078951 ko05034 Alcoholism 3/337 238/7206 0.00711903648871 ko00592 alpha-Linolenic acid metabolism 4/337 19/7206 0.0104208146377 ko03050 Proteasome 7/337 54/7206 0.0122591332874 ko04728 Dopaminergic synapse 2/337 185/7206 0.012499356482 ko00120 Primary bile acid biosynthesis 4/337 20/7206 0.0125556477854 ko04136 Autophagy - other 5/337 31/7206 0.0135331065456 ko04064 NF-kappa B signaling pathway 10/337 96/7206 0.0138461571389 ko04916 Melanogenesis 1/337 142/7206 0.0148492345816 ko03040 Spliceosome 1/337 145/7206 0.0151132368914 ko04110 Cell cycle 1/337 145/7206 0.0151132368914 ko04940 Type I diabetes mellitus 5/337 32/7206 0.0154414531341 ko04062 Chemokine signaling pathway 17/337 201/7206 0.0163410182932 ko04080 Neuroactive ligand-receptor interaction 10/337 423/7206 0.0171430434073 ko05161 Hepatitis B 15/337 173/7206 0.0174180901198 ko04662 B cell receptor signaling pathway 9/337 88/7206 0.0212527130195 ko04713 Circadian entrainment 1/337 136/7206 0.021750346975 ko05132 Salmonella infection 10/337 98/7206 0.0247012402971 ko01200 Carbon metabolism 1/337 128/7206 0.0315100966979 ko03010 Ribosome 1/337 129/7206 0.0318290220113 ko00590 Arachidonic acid metabolism 6/337 52/7206 0.0332855258588 ko04933 AGE-RAGE signaling pathway in diabetic complications 12/337 135/7206 0.0351208987748 ko04390 Hippo signaling pathway 3/337 188/7206 0.0356788453638 ko05323 Rheumatoid arthritis 9/337 89/7206 0.0364189377687 ko04068 FoxO signaling pathway 14/337 167/7206 0.0377665036147 ko04960 Aldosterone-regulated sodium reabsorption 5/337 41/7206 0.0409231281385 ko05416 Viral myocarditis 6/337 55/7206 0.0422343315231 ko05418 Fluid shear stress and atherosclerosis 14/337 173/7206 0.0423289048197 ko04911 Insulin secretion 1/337 117/7206 0.0446119921285 ko00966 Glucosinolate biosynthesis 1/337 1/7206 0.0467665834028 ko04310 Wnt signaling pathway 3/337 181/7206 0.0488357250029 ko04724 Glutamatergic synapse 2/337 152/7206 0.0491657592347