ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 11/113 30/7206 3.66212798757e-13 ko04060 Cytokine-cytokine receptor interaction 20/113 191/7206 1.00163745891e-11 ko04650 Natural killer cell mediated cytotoxicity 13/113 97/7206 2.6699819879e-09 ko05162 Measles 13/113 120/7206 3.71517672175e-08 ko05152 Tuberculosis 15/113 187/7206 1.8156814615e-07 ko05320 Autoimmune thyroid disease 7/113 29/7206 2.27097201172e-07 ko04612 Antigen processing and presentation 10/113 77/7206 2.73834088229e-07 ko05164 Influenza A 14/113 167/7206 2.79902916396e-07 ko04062 Chemokine signaling pathway 15/113 201/7206 4.65630205927e-07 ko05330 Allograft rejection 6/113 24/7206 1.39170176947e-06 ko04620 Toll-like receptor signaling pathway 10/113 100/7206 3.1965840267e-06 ko05144 Malaria 7/113 45/7206 5.3687275197e-06 ko05140 Leishmaniasis 8/113 75/7206 2.00761975445e-05 ko04660 T cell receptor signaling pathway 10/113 124/7206 2.20025914353e-05 ko05321 Inflammatory bowel disease (IBD) 7/113 56/7206 2.38042180979e-05 ko05168 Herpes simplex infection 12/113 182/7206 2.50624675167e-05 ko05145 Toxoplasmosis 10/113 126/7206 2.53057858648e-05 ko04659 Th17 cell differentiation 9/113 106/7206 3.83758119489e-05 ko04145 Phagosome 11/113 162/7206 4.24254395637e-05 ko04380 Osteoclast differentiation 10/113 134/7206 4.31309612282e-05 ko04217 Necroptosis 11/113 178/7206 0.000100057594953 ko05310 Asthma 4/113 17/7206 0.000116564107747 ko04064 NF-kappa B signaling pathway 8/113 96/7206 0.000120110254639 ko05332 Graft-versus-host disease 4/113 18/7206 0.000148063128061 ko04664 Fc epsilon RI signaling pathway 7/113 77/7206 0.000188299652946 ko05416 Viral myocarditis 6/113 55/7206 0.000201877096447 ko05150 Staphylococcus aureus infection 5/113 36/7206 0.000221934536501 ko05161 Hepatitis B 10/113 173/7206 0.000360397645721 ko05133 Pertussis 7/113 87/7206 0.000402313262681 ko04658 Th1 and Th2 cell differentiation 7/113 96/7206 0.000731027392223 ko05167 Kaposi's sarcoma-associated herpesvirus infection 10/113 191/7206 0.000786020991552 ko04630 Jak-STAT signaling pathway 8/113 132/7206 0.00104598546467 ko04940 Type I diabetes mellitus 4/113 32/7206 0.00146929334497 ko04670 Leukocyte transendothelial migration 8/113 151/7206 0.00246663943475 ko04672 Intestinal immune network for IgA production 4/113 37/7206 0.00254103922162 ko04666 Fc gamma R-mediated phagocytosis 7/113 122/7206 0.00294418166325 ko04621 NOD-like receptor signaling pathway 8/113 157/7206 0.00314074639558 ko04640 Hematopoietic cell lineage 5/113 64/7206 0.003169615008 ko04514 Cell adhesion molecules (CAMs) 7/113 130/7206 0.00419193564096 ko03050 Proteasome 4/113 54/7206 0.00992790417417 ko04662 B cell receptor signaling pathway 5/113 88/7206 0.0121161554893 ko05323 Rheumatoid arthritis 5/113 89/7206 0.0126807964298 ko04622 RIG-I-like receptor signaling pathway 4/113 62/7206 0.0159226925835 ko05142 Chagas disease (American trypanosomiasis) 6/113 130/7206 0.0161252555858 ko04210 Apoptosis 7/113 180/7206 0.0226860166339 ko05020 Prion diseases 3/113 40/7206 0.0243600128912 ko05160 Hepatitis C 6/113 153/7206 0.0327556534662 ko04611 Platelet activation 6/113 163/7206 0.0425689977245 ko05166 HTLV-I infection 9/113 292/7206 0.0482977335284