ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 12/75 157/7206 6.00190462886e-08 ko05164 Influenza A 12/75 167/7206 1.191015451e-07 ko04668 TNF signaling pathway 10/75 120/7206 3.74695720709e-07 ko04060 Cytokine-cytokine receptor interaction 12/75 191/7206 5.15933133272e-07 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/75 191/7206 5.15933133272e-07 ko04064 NF-kappa B signaling pathway 9/75 96/7206 5.50541923277e-07 ko04380 Osteoclast differentiation 10/75 134/7206 1.04807240429e-06 ko05152 Tuberculosis 11/75 187/7206 3.08563240788e-06 ko04623 Cytosolic DNA-sensing pathway 6/75 41/7206 3.49663044759e-06 ko05161 Hepatitis B 10/75 173/7206 1.05549526919e-05 ko05168 Herpes simplex infection 10/75 182/7206 1.64819389478e-05 ko04662 B cell receptor signaling pathway 7/75 88/7206 3.22440852809e-05 ko04622 RIG-I-like receptor signaling pathway 6/75 62/7206 4.02213947943e-05 ko05145 Toxoplasmosis 8/75 126/7206 4.42232699214e-05 ko04658 Th1 and Th2 cell differentiation 7/75 96/7206 5.665661344e-05 ko04630 Jak-STAT signaling pathway 8/75 132/7206 6.16835902955e-05 ko04217 Necroptosis 9/75 178/7206 8.63727082477e-05 ko04210 Apoptosis 9/75 180/7206 9.41504023888e-05 ko05160 Hepatitis C 8/75 153/7206 0.000173927827971 ko05162 Measles 7/75 120/7206 0.000231803033736 ko04660 T cell receptor signaling pathway 7/75 124/7206 0.000283770447722 ko05140 Leishmaniasis 5/75 75/7206 0.00104513967767 ko04612 Antigen processing and presentation 5/75 77/7206 0.00117730575558 ko04657 IL-17 signaling pathway 5/75 87/7206 0.00203143610551 ko05142 Chagas disease (American trypanosomiasis) 6/75 130/7206 0.00223443804478 ko05321 Inflammatory bowel disease (IBD) 4/75 56/7206 0.00264102731673 ko04620 Toll-like receptor signaling pathway 5/75 100/7206 0.00372863300653 ko04062 Chemokine signaling pathway 7/75 201/7206 0.0047225977272 ko04659 Th17 cell differentiation 5/75 106/7206 0.00478307756514 ko05169 Epstein-Barr virus infection 7/75 206/7206 0.00539651222052 ko05215 Prostate cancer 5/75 111/7206 0.00581149437066 ko04672 Intestinal immune network for IgA production 3/75 37/7206 0.00652774799959 ko05203 Viral carcinogenesis 8/75 277/7206 0.00779693144543 ko05166 HTLV-I infection 8/75 292/7206 0.0105552236136 ko04917 Prolactin signaling pathway 4/75 87/7206 0.0125718142494 ko05133 Pertussis 4/75 87/7206 0.0125718142494 ko05222 Small cell lung cancer 4/75 89/7206 0.0135780548257 ko04931 Insulin resistance 5/75 137/7206 0.0137607685681 ko05120 Epithelial cell signaling in Helicobacter pylori infection 4/75 92/7206 0.0151814729036 ko04650 Natural killer cell mediated cytotoxicity 4/75 97/7206 0.0181109503321 ko05146 Amoebiasis 4/75 99/7206 0.0193747385092 ko00512 Mucin type O-glycan biosynthesis 2/75 29/7206 0.0362071527044 ko05340 Primary immunodeficiency 2/75 30/7206 0.0385367312905 ko05134 Legionellosis 3/75 74/7206 0.0414785278233 ko05014 Amyotrophic lateral sclerosis (ALS) 3/75 74/7206 0.0414785278233 ko04115 p53 signaling pathway 3/75 74/7206 0.0414785278233 ko01524 Platinum drug resistance 3/75 76/7206 0.044331178792 ko04664 Fc epsilon RI signaling pathway 3/75 77/7206 0.0457934998833 ko04010 MAPK signaling pathway 7/75 321/7206 0.0486776764825