ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	95/759	145/7206	1.09771674886e-58
ko04110	Cell cycle	71/759	145/7206	3.26609290393e-32
ko04111	Cell cycle - yeast	48/759	90/7206	3.55317442272e-24
ko03030	DNA replication	30/759	38/7206	6.02908631042e-23
ko03013	RNA transport	65/759	166/7206	9.79148167103e-23
ko03460	Fanconi anemia pathway	31/759	51/7206	2.80496849051e-18
ko04113	Meiosis - yeast	34/759	70/7206	7.85519203958e-16
ko03008	Ribosome biogenesis in eukaryotes	36/759	79/7206	1.42214450182e-15
ko03440	Homologous recombination	24/759	41/7206	6.54156203343e-14
ko03420	Nucleotide excision repair	25/759	46/7206	2.02616334958e-13
ko03410	Base excision repair	22/759	38/7206	1.01496803954e-12
ko03015	mRNA surveillance pathway	35/759	93/7206	3.56117619495e-12
ko03430	Mismatch repair	16/759	22/7206	8.03951763026e-12
ko00240	Pyrimidine metabolism	38/759	110/7206	8.990603344e-12
ko04144	Endocytosis	8/759	342/7206	6.64712607188e-09
ko05010	Alzheimer's disease	2/759	202/7206	7.32120400155e-08
ko03022	Basal transcription factors	18/759	44/7206	1.52084596707e-07
ko04060	Cytokine-cytokine receptor interaction	2/759	191/7206	2.44310641152e-07
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/759	182/7206	5.29536816216e-07
ko03018	RNA degradation	25/759	84/7206	8.90715566329e-07
ko04022	cGMP-PKG signaling pathway	4/759	216/7206	1.31846968966e-06
ko04024	cAMP signaling pathway	8/759	279/7206	2.00713324604e-06
ko03020	RNA polymerase	13/759	29/7206	2.41797896749e-06
ko05166	HTLV-I infection	56/759	292/7206	5.98834096874e-06
ko05012	Parkinson's disease	2/759	155/7206	8.25882753731e-06
ko04723	Retrograde endocannabinoid signaling	3/759	175/7206	8.49011551562e-06
ko04621	NOD-like receptor signaling pathway	2/759	157/7206	8.49624397237e-06
ko04330	Notch signaling pathway	19/759	62/7206	1.14071412941e-05
ko04724	Glutamatergic synapse	2/759	152/7206	1.22303926705e-05
ko00230	Purine metabolism	41/759	194/7206	1.29181753867e-05
ko03010	Ribosome	1/759	129/7206	1.56352379716e-05
ko04072	Phospholipase D signaling pathway	5/759	197/7206	2.91534077859e-05
ko04921	Oxytocin signaling pathway	6/759	209/7206	4.83276550594e-05
ko04911	Insulin secretion	1/759	117/7206	5.14388967999e-05
ko05203	Viral carcinogenesis	51/759	277/7206	5.48160675854e-05
ko04261	Adrenergic signaling in cardiomyocytes	6/759	205/7206	6.79962290975e-05
ko04270	Vascular smooth muscle contraction	3/759	154/7206	8.38920040269e-05
ko04972	Pancreatic secretion	1/759	111/7206	0.000118555716171
ko05322	Systemic lupus erythematosus	32/759	151/7206	0.000125639345787
ko05168	Herpes simplex infection	36/759	182/7206	0.000189981308929
ko04725	Cholinergic synapse	4/759	160/7206	0.000207904779581
ko04713	Circadian entrainment	3/759	136/7206	0.00034462424103
ko04726	Serotonergic synapse	3/759	137/7206	0.000348559654328
ko04114	Oocyte meiosis	29/759	139/7206	0.00036925849627
ko04650	Natural killer cell mediated cytotoxicity	1/759	97/7206	0.000373901634352
ko04971	Gastric acid secretion	1/759	98/7206	0.000374723410459
ko05146	Amoebiasis	1/759	99/7206	0.00038161037465
ko04062	Chemokine signaling pathway	7/759	201/7206	0.000394472449455
ko04142	Lysosome	4/759	151/7206	0.000413567117504
ko04014	Ras signaling pathway	13/759	279/7206	0.000467319149457
ko04915	Estrogen signaling pathway	3/759	131/7206	0.000495192639012
ko04380	Osteoclast differentiation	3/759	134/7206	0.000510452551089
ko05217	Basal cell carcinoma	17/759	68/7206	0.000513516615618
ko04974	Protein digestion and absorption	1/759	96/7206	0.000580846527944
ko04120	Ubiquitin mediated proteolysis	28/759	138/7206	0.000618226619019
ko04371	Apelin signaling pathway	6/759	177/7206	0.000702318653021
ko04727	GABAergic synapse	2/759	110/7206	0.000813268728386
ko04070	Phosphatidylinositol signaling system	2/759	112/7206	0.000858847946698
ko05414	Dilated cardiomyopathy	2/759	112/7206	0.000858847946698
ko04530	Tight junction	10/759	228/7206	0.000951572542299
ko05152	Tuberculosis	7/759	187/7206	0.000992791253657
ko04925	Aldosterone synthesis and secretion	2/759	105/7206	0.0011705972578
ko04659	Th17 cell differentiation	2/759	106/7206	0.0011781732482
ko04510	Focal adhesion	11/759	240/7206	0.0012238852869
ko04662	B cell receptor signaling pathway	1/759	88/7206	0.00125643934331
ko04146	Peroxisome	1/759	89/7206	0.0013061158059
ko04728	Dopaminergic synapse	7/759	185/7206	0.00140373703291
ko04668	TNF signaling pathway	3/759	120/7206	0.00144440969437
ko04151	PI3K-Akt signaling pathway	23/759	390/7206	0.00160383430876
ko04933	AGE-RAGE signaling pathway in diabetic complications	4/759	135/7206	0.00164144242082
ko05142	Chagas disease (American trypanosomiasis)	4/759	130/7206	0.00230304430427
ko04514	Cell adhesion molecules (CAMs)	4/759	130/7206	0.00230304430427
ko05169	Epstein-Barr virus infection	36/759	206/7206	0.00248727326422
ko00564	Glycerophospholipid metabolism	2/759	99/7206	0.00249992630343
ko05410	Hypertrophic cardiomyopathy (HCM)	2/759	100/7206	0.00256914785441
ko04620	Toll-like receptor signaling pathway	2/759	100/7206	0.00256914785441
ko04071	Sphingolipid signaling pathway	6/759	162/7206	0.00257629912973
ko04740	Olfactory transduction	1/759	80/7206	0.0027142315566
ko04810	Regulation of actin cytoskeleton	14/759	264/7206	0.00297204895272
ko04914	Progesterone-mediated oocyte maturation	21/759	104/7206	0.00317468848491
ko01200	Carbon metabolism	4/759	128/7206	0.00325256140905
ko04712	Circadian rhythm - plant	4/759	7/7206	0.003292328781
ko04139	Mitophagy - yeast	10/759	37/7206	0.00391290254457
ko05140	Leishmaniasis	1/759	75/7206	0.00392455702743
ko04923	Regulation of lipolysis in adipocytes	1/759	77/7206	0.00410526983861
ko04750	Inflammatory mediator regulation of TRP channels	4/759	122/7206	0.00449918544874
ko04066	HIF-1 signaling pathway	4/759	123/7206	0.00449955020373
ko04931	Insulin resistance	5/759	137/7206	0.00466156687449
ko04670	Leukocyte transendothelial migration	6/759	151/7206	0.00468453170815
ko00562	Inositol phosphate metabolism	2/759	89/7206	0.00509784115182
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/759	92/7206	0.00529450676649
ko04152	AMPK signaling pathway	7/759	161/7206	0.00620523422455
ko04145	Phagosome	7/759	162/7206	0.00621095166852
ko04611	Platelet activation	7/759	163/7206	0.00625483622363
ko05231	Choline metabolism in cancer	5/759	134/7206	0.00643864249654
ko04924	Renin secretion	2/759	86/7206	0.00732942028033
ko05133	Pertussis	2/759	87/7206	0.007413918456
ko04218	Cellular senescence	30/759	177/7206	0.00861405991117
ko04630	Jak-STAT signaling pathway	5/759	132/7206	0.00910077912732
ko04138	Autophagy - yeast	2/759	81/7206	0.0104993080933
ko05160	Hepatitis C	7/759	153/7206	0.0111565547645
ko05132	Salmonella infection	3/759	98/7206	0.0117648070594
ko05032	Morphine addiction	4/759	110/7206	0.0120072803969
ko05145	Toxoplasmosis	5/759	126/7206	0.0120490318587
ko04015	Rap1 signaling pathway	17/759	278/7206	0.012441014897
ko04640	Hematopoietic cell lineage	1/759	64/7206	0.0125631939259
ko05034	Alcoholism	37/759	238/7206	0.0133894524831
ko04140	Autophagy - animal	8/759	164/7206	0.0139680972074
ko04730	Long-term depression	2/759	78/7206	0.0149987488476
ko04010	MAPK signaling pathway	21/759	321/7206	0.0153425840674
ko04912	GnRH signaling pathway	5/759	122/7206	0.0163959306578
ko04660	T cell receptor signaling pathway	5/759	124/7206	0.0168974438901
ko04340	Hedgehog signaling pathway	12/759	58/7206	0.0175645600128
ko04722	Neurotrophin signaling pathway	8/759	160/7206	0.0184298780515
ko04310	Wnt signaling pathway	29/759	181/7206	0.0193882080561
ko04550	Signaling pathways regulating pluripotency of stem cells	27/759	165/7206	0.0199909550197
ko05202	Transcriptional misregulation in cancer	30/759	188/7206	0.021240915147
ko05134	Legionellosis	2/759	74/7206	0.0213681796493
ko04910	Insulin signaling pathway	9/759	172/7206	0.0225970576735
ko05323	Rheumatoid arthritis	3/759	89/7206	0.0226898033747
ko05031	Amphetamine addiction	3/759	91/7206	0.0234086576905
ko04922	Glucagon signaling pathway	6/759	128/7206	0.0282403048889
ko04213	Longevity regulating pathway - multiple species	3/759	86/7206	0.0319036543709
ko04918	Thyroid hormone synthesis	3/759	86/7206	0.0319036543709
ko05030	Cocaine addiction	2/759	73/7206	0.0319219759838
ko04115	p53 signaling pathway	14/759	74/7206	0.0330039503542
ko04141	Protein processing in endoplasmic reticulum	11/759	184/7206	0.0386053709617
ko00590	Arachidonic acid metabolism	1/759	52/7206	0.0391439500277
ko04012	ErbB signaling pathway	5/759	109/7206	0.0400737818333