ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	35/544	56/7206	5.6732195029e-26
ko04724	Glutamatergic synapse	54/544	152/7206	1.2915544168e-23
ko04727	GABAergic synapse	44/544	110/7206	8.23970609839e-22
ko05032	Morphine addiction	43/544	110/7206	7.15994677867e-21
ko04080	Neuroactive ligand-receptor interaction	88/544	423/7206	1.35434942632e-19
ko04723	Retrograde endocannabinoid signaling	50/544	175/7206	2.64886123803e-17
ko04728	Dopaminergic synapse	51/544	185/7206	6.64226089594e-17
ko04713	Circadian entrainment	41/544	136/7206	2.8520651936e-15
ko04024	cAMP signaling pathway	59/544	279/7206	1.18726744377e-13
ko04725	Cholinergic synapse	40/544	160/7206	5.4615945734e-12
ko05030	Cocaine addiction	24/544	73/7206	2.53022995403e-10
ko04911	Insulin secretion	31/544	117/7206	3.00075720232e-10
ko04010	MAPK signaling pathway	56/544	321/7206	1.66141888542e-09
ko04921	Oxytocin signaling pathway	42/544	209/7206	2.60189856749e-09
ko04261	Adrenergic signaling in cardiomyocytes	41/544	205/7206	4.70510300822e-09
ko05031	Amphetamine addiction	25/544	91/7206	7.27604423154e-09
ko04020	Calcium signaling pathway	48/544	265/7206	7.43394512e-09
ko04721	Synaptic vesicle cycle	23/544	80/7206	1.13230359841e-08
ko04720	Long-term potentiation	24/544	99/7206	1.99288791186e-07
ko04726	Serotonergic synapse	29/544	137/7206	2.55302279032e-07
ko04514	Cell adhesion molecules (CAMs)	28/544	130/7206	2.81641178794e-07
ko04742	Taste transduction	18/544	61/7206	2.93232020965e-07
ko04072	Phospholipase D signaling pathway	33/544	197/7206	1.25294132185e-05
ko04730	Long-term depression	18/544	78/7206	1.41130878531e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/544	79/7206	1.70203353508e-05
ko05414	Dilated cardiomyopathy	21/544	112/7206	7.88391093434e-05
ko04260	Cardiac muscle contraction	19/544	98/7206	0.000107646284948
ko05203	Viral carcinogenesis	6/544	277/7206	0.000111726750522
ko04915	Estrogen signaling pathway	23/544	131/7206	0.00013633369872
ko04360	Axon guidance	34/544	233/7206	0.000196723666445
ko04970	Salivary secretion	18/544	95/7206	0.000220156056645
ko04925	Aldosterone synthesis and secretion	19/544	105/7206	0.000277087728032
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/544	14/7206	0.000319903930469
ko03040	Spliceosome	1/544	145/7206	0.000326182744657
ko05014	Amyotrophic lateral sclerosis (ALS)	15/544	74/7206	0.000340459653531
ko04972	Pancreatic secretion	19/544	111/7206	0.000727813924019
ko05410	Hypertrophic cardiomyopathy (HCM)	17/544	100/7206	0.00156196401755
ko04060	Cytokine-cytokine receptor interaction	4/544	191/7206	0.00192991858916
ko04022	cGMP-PKG signaling pathway	29/544	216/7206	0.00230778166458
ko03013	RNA transport	3/544	166/7206	0.00247510406788
ko05231	Choline metabolism in cancer	20/544	134/7206	0.00269552516638
ko04621	NOD-like receptor signaling pathway	3/544	157/7206	0.00331584269832
ko05322	Systemic lupus erythematosus	3/544	151/7206	0.00465432109188
ko04666	Fc gamma R-mediated phagocytosis	18/544	122/7206	0.00510590775408
ko04014	Ras signaling pathway	34/544	279/7206	0.00516282762469
ko05034	Alcoholism	30/544	238/7206	0.00553370539817
ko04070	Phosphatidylinositol signaling system	17/544	112/7206	0.00560181307443
ko04930	Type II diabetes mellitus	10/544	54/7206	0.00641343603948
ko04110	Cell cycle	3/544	145/7206	0.00652416885281
ko05168	Herpes simplex infection	5/544	182/7206	0.00976379497881
ko04141	Protein processing in endoplasmic reticulum	5/544	184/7206	0.0100001071847
ko04120	Ubiquitin mediated proteolysis	3/544	138/7206	0.0132095823928
ko04923	Regulation of lipolysis in adipocytes	12/544	77/7206	0.0143853810801
ko04144	Endocytosis	38/544	342/7206	0.0153254586279
ko05131	Shigellosis	1/544	82/7206	0.0199732338788
ko05164	Influenza A	5/544	167/7206	0.0245864622472
ko04540	Gap junction	17/544	128/7206	0.0258667835136
ko04612	Antigen processing and presentation	1/544	77/7206	0.0289755257186
ko04071	Sphingolipid signaling pathway	20/544	162/7206	0.0332287012254
ko04973	Carbohydrate digestion and absorption	7/544	42/7206	0.0359431076329
ko00515	Mannose type O-glycan biosynthesis	5/544	25/7206	0.0362004288607
ko04710	Circadian rhythm	7/544	43/7206	0.040253047277
ko04670	Leukocyte transendothelial migration	5/544	151/7206	0.0427151330111