ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	27/482	56/7206	1.14034451695e-17
ko04080	Neuroactive ligand-receptor interaction	77/482	423/7206	8.52840923929e-17
ko04724	Glutamatergic synapse	42/482	152/7206	5.18997279327e-16
ko05032	Morphine addiction	34/482	110/7206	9.14539333642e-15
ko04713	Circadian entrainment	37/482	136/7206	5.30855834465e-14
ko04727	GABAergic synapse	32/482	110/7206	3.79626675549e-13
ko04723	Retrograde endocannabinoid signaling	41/482	175/7206	5.32192780544e-13
ko04728	Dopaminergic synapse	40/482	185/7206	1.58994401957e-11
ko04911	Insulin secretion	29/482	117/7206	3.62063155419e-10
ko04721	Synaptic vesicle cycle	22/482	80/7206	6.32956011384e-09
ko04726	Serotonergic synapse	28/482	137/7206	7.1114044353e-08
ko04725	Cholinergic synapse	30/482	160/7206	1.8303788108e-07
ko04730	Long-term depression	19/482	78/7206	5.58700100457e-07
ko04070	Phosphatidylinositol signaling system	23/482	112/7206	9.7626178178e-07
ko04024	cAMP signaling pathway	41/482	279/7206	1.79420959856e-06
ko04261	Adrenergic signaling in cardiomyocytes	32/482	205/7206	5.47302439019e-06
ko04020	Calcium signaling pathway	38/482	265/7206	6.81504569742e-06
ko04921	Oxytocin signaling pathway	32/482	209/7206	7.87916186075e-06
ko04970	Salivary secretion	19/482	95/7206	1.28800882473e-05
ko05031	Amphetamine addiction	18/482	91/7206	2.54545545546e-05
ko04742	Taste transduction	14/482	61/7206	3.60657866692e-05
ko05030	Cocaine addiction	15/482	73/7206	7.56918515136e-05
ko04720	Long-term potentiation	18/482	99/7206	8.21216637051e-05
ko04972	Pancreatic secretion	19/482	111/7206	0.00012220276806
ko04745	Phototransduction - fly	10/482	38/7206	0.00014030748455
ko04960	Aldosterone-regulated sodium reabsorption	10/482	41/7206	0.000277429175609
ko04514	Cell adhesion molecules (CAMs)	20/482	130/7206	0.000476154483487
ko04260	Cardiac muscle contraction	16/482	98/7206	0.00071210041584
ko05322	Systemic lupus erythematosus	1/482	151/7206	0.000722019537104
ko04022	cGMP-PKG signaling pathway	27/482	216/7206	0.00134142775946
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/482	59/7206	0.00158979386517
ko04060	Cytokine-cytokine receptor interaction	3/482	191/7206	0.00173982755718
ko00562	Inositol phosphate metabolism	14/482	89/7206	0.0021721825047
ko04964	Proximal tubule bicarbonate reclamation	7/482	29/7206	0.00245797883274
ko04930	Type II diabetes mellitus	10/482	54/7206	0.00270418620787
ko05203	Viral carcinogenesis	7/482	277/7206	0.00292869706229
ko04971	Gastric acid secretion	15/482	98/7206	0.00310267956999
ko04925	Aldosterone synthesis and secretion	15/482	105/7206	0.00466800638202
ko03013	RNA transport	3/482	166/7206	0.00677791149709
ko05168	Herpes simplex infection	4/482	182/7206	0.00986686262646
ko04740	Olfactory transduction	12/482	80/7206	0.0103071643867
ko04010	MAPK signaling pathway	33/482	321/7206	0.0116687210301
ko02024	Quorum sensing	4/482	15/7206	0.0149259664825
ko04360	Axon guidance	25/482	233/7206	0.016195363779
ko05164	Influenza A	4/482	167/7206	0.0183875666344
ko04072	Phospholipase D signaling pathway	22/482	197/7206	0.0192225123686
ko04014	Ras signaling pathway	29/482	279/7206	0.0192232765516
ko00513	Various types of N-glycan biosynthesis	7/482	42/7206	0.020059337868
ko04973	Carbohydrate digestion and absorption	7/482	42/7206	0.020059337868
ko05166	HTLV-I infection	10/482	292/7206	0.0221872372269
ko00680	Methane metabolism	6/482	34/7206	0.0235095574878
ko04120	Ubiquitin mediated proteolysis	3/482	138/7206	0.0250194350043
ko04750	Inflammatory mediator regulation of TRP channels	15/482	122/7206	0.0254556390087
ko04966	Collecting duct acid secretion	5/482	26/7206	0.0267625368546
ko04626	Plant-pathogen interaction	4/482	18/7206	0.028545534324
ko04657	IL-17 signaling pathway	1/482	87/7206	0.0296051209733
ko05014	Amyotrophic lateral sclerosis (ALS)	10/482	74/7206	0.0304583428625
ko00240	Pyrimidine metabolism	2/482	110/7206	0.0334107116505
ko04510	Focal adhesion	8/482	240/7206	0.0343834725059
ko04071	Sphingolipid signaling pathway	18/482	162/7206	0.0362509585732
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	10/482	79/7206	0.0409152746242