ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	30/572	56/7206	4.42774501093e-19
ko04724	Glutamatergic synapse	48/572	152/7206	1.01050810878e-17
ko04080	Neuroactive ligand-receptor interaction	86/572	423/7206	4.58323141908e-17
ko04728	Dopaminergic synapse	50/572	185/7206	2.63966386064e-15
ko04721	Synaptic vesicle cycle	31/572	80/7206	1.25526535785e-14
ko04727	GABAergic synapse	32/572	110/7206	3.8955468547e-11
ko04723	Retrograde endocannabinoid signaling	40/572	175/7206	5.07677314131e-10
ko04713	Circadian entrainment	34/572	136/7206	8.65559410102e-10
ko05032	Morphine addiction	30/572	110/7206	9.16813780907e-10
ko05030	Cocaine addiction	23/572	73/7206	4.14525516602e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	22/572	74/7206	2.9923644039e-08
ko04514	Cell adhesion molecules (CAMs)	30/572	130/7206	6.24746037116e-08
ko04911	Insulin secretion	27/572	117/7206	2.87718336068e-07
ko05031	Amphetamine addiction	23/572	91/7206	3.9213292616e-07
ko04360	Axon guidance	41/572	233/7206	8.62585770041e-07
ko04725	Cholinergic synapse	31/572	160/7206	3.83042935944e-06
ko04726	Serotonergic synapse	27/572	137/7206	7.43366838853e-06
ko04024	cAMP signaling pathway	43/572	279/7206	2.09816997674e-05
ko04010	MAPK signaling pathway	47/572	321/7206	3.05841657031e-05
ko03040	Spliceosome	1/572	145/7206	0.000136315308228
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/572	59/7206	0.000156855025946
ko04261	Adrenergic signaling in cardiomyocytes	32/572	205/7206	0.000187725985886
ko04060	Cytokine-cytokine receptor interaction	3/572	191/7206	0.00019554259298
ko04720	Long-term potentiation	19/572	99/7206	0.000239023490513
ko04964	Proximal tubule bicarbonate reclamation	9/572	29/7206	0.000277270944568
ko04120	Ubiquitin mediated proteolysis	1/572	138/7206	0.000319801913387
ko04970	Salivary secretion	18/572	95/7206	0.000408080552841
ko05203	Viral carcinogenesis	8/572	277/7206	0.000601075145431
ko04742	Taste transduction	13/572	61/7206	0.000812756613896
ko04730	Long-term depression	15/572	78/7206	0.0010354318686
ko03013	RNA transport	3/572	166/7206	0.00116589747861
ko05164	Influenza A	3/572	167/7206	0.00118423620891
ko04950	Maturity onset diabetes of the young	8/572	29/7206	0.00143973824604
ko04974	Protein digestion and absorption	17/572	96/7206	0.00163558119713
ko05168	Herpes simplex infection	4/572	182/7206	0.00191291353034
ko01200	Carbon metabolism	2/572	128/7206	0.00275645188221
ko04014	Ras signaling pathway	36/572	279/7206	0.00315157988468
ko04978	Mineral absorption	9/572	40/7206	0.0034453811854
ko04972	Pancreatic secretion	18/572	111/7206	0.00367660500661
ko04976	Bile secretion	14/572	80/7206	0.00506725320814
ko05162	Measles	2/572	120/7206	0.00568821060696
ko05034	Alcoholism	31/572	238/7206	0.00674288864671
ko04621	NOD-like receptor signaling pathway	4/572	157/7206	0.0068655467585
ko04540	Gap junction	19/572	128/7206	0.00732414716353
ko04512	ECM-receptor interaction	13/572	79/7206	0.0101606098987
ko00240	Pyrimidine metabolism	2/572	110/7206	0.0115866364645
ko04150	mTOR signaling pathway	6/572	184/7206	0.0126067427049
ko04141	Protein processing in endoplasmic reticulum	6/572	184/7206	0.0126067427049
ko04260	Cardiac muscle contraction	15/572	98/7206	0.0126574687277
ko03018	RNA degradation	1/572	84/7206	0.0136134051747
ko04966	Collecting duct acid secretion	6/572	26/7206	0.014222400709
ko04151	PI3K-Akt signaling pathway	44/572	390/7206	0.0157319511752
ko04611	Platelet activation	5/572	163/7206	0.0178327789149
ko03008	Ribosome biogenesis in eukaryotes	1/572	79/7206	0.0198137138099
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/572	8/7206	0.0205924175312
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/572	14/7206	0.0206865140307
ko00430	Taurine and hypotaurine metabolism	4/572	14/7206	0.0206865140307
ko05146	Amoebiasis	2/572	99/7206	0.0231295536095
ko04071	Sphingolipid signaling pathway	21/572	162/7206	0.0258426873295
ko02024	Quorum sensing	4/572	15/7206	0.0264803591049
ko00310	Lysine degradation	1/572	73/7206	0.0286782519822
ko00010	Glycolysis / Gluconeogenesis	1/572	74/7206	0.0287866199723
ko05213	Endometrial cancer	10/572	62/7206	0.0288258851267
ko04391	Hippo signaling pathway - fly	13/572	90/7206	0.0295355423323
ko01524	Platinum drug resistance	1/572	76/7206	0.0295593120509
ko04612	Antigen processing and presentation	1/572	77/7206	0.0302240775603
ko04923	Regulation of lipolysis in adipocytes	1/572	77/7206	0.0302240775603
ko04015	Rap1 signaling pathway	32/572	278/7206	0.0309041780725
ko05224	Breast cancer	22/572	174/7206	0.0314986318109
ko05322	Systemic lupus erythematosus	5/572	151/7206	0.0319078630344
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/572	79/7206	0.0321135666911
ko04064	NF-kappa B signaling pathway	2/572	96/7206	0.0335538425537
ko04940	Type I diabetes mellitus	6/572	32/7206	0.0374242411499
ko04140	Autophagy - animal	6/572	164/7206	0.0396734290912
ko04960	Aldosterone-regulated sodium reabsorption	7/572	41/7206	0.0404164377925
ko00350	Tyrosine metabolism	6/572	33/7206	0.0427926589539
ko00230	Purine metabolism	8/572	194/7206	0.0433321024019
ko04214	Apoptosis - fly	1/572	72/7206	0.0438348147644
ko04973	Carbohydrate digestion and absorption	7/572	42/7206	0.0453208288
ko04962	Vasopressin-regulated water reabsorption	9/572	58/7206	0.0458345758063
ko04146	Peroxisome	2/572	89/7206	0.0460307804287
ko05120	Epithelial cell signaling in Helicobacter pylori infection	13/572	92/7206	0.0482485871785
ko05216	Thyroid cancer	6/572	34/7206	0.0486204730889