ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	29/600	56/7206	2.23154424634e-17
ko04724	Glutamatergic synapse	48/600	152/7206	7.17198095825e-17
ko04728	Dopaminergic synapse	49/600	185/7206	7.9515921202e-14
ko04080	Neuroactive ligand-receptor interaction	81/600	423/7206	2.61007888808e-13
ko04727	GABAergic synapse	35/600	110/7206	1.00620933656e-12
ko04721	Synaptic vesicle cycle	29/600	80/7206	2.30490023606e-12
ko05032	Morphine addiction	32/600	110/7206	1.36349935307e-10
ko04723	Retrograde endocannabinoid signaling	41/600	175/7206	5.92157736735e-10
ko04713	Circadian entrainment	34/600	136/7206	3.03683878421e-09
ko04360	Axon guidance	46/600	233/7206	1.98784151789e-08
ko04725	Cholinergic synapse	36/600	160/7206	2.13576047227e-08
ko04514	Cell adhesion molecules (CAMs)	31/600	130/7206	5.03613116447e-08
ko04911	Insulin secretion	29/600	117/7206	5.51119440606e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	19/600	74/7206	6.33705714904e-06
ko05030	Cocaine addiction	18/600	73/7206	2.02743973983e-05
ko04726	Serotonergic synapse	27/600	137/7206	2.38320802246e-05
ko05031	Amphetamine addiction	20/600	91/7206	4.35573865609e-05
ko04261	Adrenergic signaling in cardiomyocytes	35/600	205/7206	4.79916366557e-05
ko05203	Viral carcinogenesis	7/600	277/7206	8.44614875654e-05
ko03040	Spliceosome	1/600	145/7206	9.37577877876e-05
ko04024	cAMP signaling pathway	42/600	279/7206	0.000141299448751
ko04010	MAPK signaling pathway	46/600	321/7206	0.000253898771273
ko05322	Systemic lupus erythematosus	2/600	151/7206	0.000459894918376
ko04060	Cytokine-cytokine receptor interaction	4/600	191/7206	0.000467263233255
ko03013	RNA transport	3/600	166/7206	0.000557715670734
ko05164	Influenza A	3/600	167/7206	0.000559027745903
ko04120	Ubiquitin mediated proteolysis	2/600	138/7206	0.000908004221338
ko05168	Herpes simplex infection	4/600	182/7206	0.000935357428343
ko04970	Salivary secretion	17/600	95/7206	0.0021826681554
ko04211	Longevity regulating pathway	2/600	123/7206	0.00270946013484
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/600	79/7206	0.00291763318298
ko04921	Oxytocin signaling pathway	30/600	209/7206	0.00311453880472
ko04391	Hippo signaling pathway - fly	16/600	90/7206	0.00316883118473
ko04611	Platelet activation	4/600	163/7206	0.00362180026272
ko05016	Huntington's disease	7/600	215/7206	0.00369925428786
ko04742	Taste transduction	12/600	61/7206	0.00390749857767
ko05162	Measles	2/600	120/7206	0.00395239119417
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/600	14/7206	0.00417484231878
ko04621	NOD-like receptor signaling pathway	4/600	157/7206	0.00495886162892
ko04972	Pancreatic secretion	18/600	111/7206	0.00509149267927
ko04512	ECM-receptor interaction	14/600	79/7206	0.00615344485014
ko05205	Proteoglycans in cancer	11/600	271/7206	0.00689526451238
ko04964	Proximal tubule bicarbonate reclamation	7/600	29/7206	0.00826832870462
ko04260	Cardiac muscle contraction	16/600	98/7206	0.00849861324496
ko04720	Long-term potentiation	16/600	99/7206	0.00904237559
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/600	182/7206	0.00930200330432
ko04730	Long-term depression	13/600	78/7206	0.0126352650369
ko04014	Ras signaling pathway	35/600	279/7206	0.014395581878
ko04974	Protein digestion and absorption	15/600	96/7206	0.014696111088
ko04966	Collecting duct acid secretion	6/600	26/7206	0.0177015688273
ko05140	Leishmaniasis	1/600	75/7206	0.0195563430097
ko04612	Antigen processing and presentation	1/600	77/7206	0.0200163382891
ko04973	Carbohydrate digestion and absorption	8/600	42/7206	0.0206772520835
ko04141	Protein processing in endoplasmic reticulum	7/600	184/7206	0.0209677281765
ko05166	HTLV-I infection	14/600	292/7206	0.0229015931534
ko04744	Phototransduction	7/600	36/7206	0.0266763434082
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/600	59/7206	0.0283183664157
ko04214	Apoptosis - fly	1/600	72/7206	0.0290086687101
ko04020	Calcium signaling pathway	32/600	265/7206	0.0306948074539
ko04146	Peroxisome	2/600	89/7206	0.0322273944215
ko04022	cGMP-PKG signaling pathway	27/600	216/7206	0.0324321423151
ko01200	Carbon metabolism	4/600	128/7206	0.033707996042
ko00240	Pyrimidine metabolism	3/600	110/7206	0.0343352161597
ko05161	Hepatitis B	7/600	173/7206	0.0362142177357
ko04151	PI3K-Akt signaling pathway	44/600	390/7206	0.0374993067863
ko04930	Type II diabetes mellitus	9/600	54/7206	0.0416663863316
ko04071	Sphingolipid signaling pathway	21/600	162/7206	0.0422334942915
ko04978	Mineral absorption	7/600	40/7206	0.044758858003
ko03018	RNA degradation	2/600	84/7206	0.0453470717773