ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	153/860	423/7206	3.03187010405e-41
ko04724	Glutamatergic synapse	78/860	152/7206	2.82480490712e-33
ko05033	Nicotine addiction	43/860	56/7206	3.17910042412e-29
ko05032	Morphine addiction	59/860	110/7206	1.06071256273e-26
ko04713	Circadian entrainment	65/860	136/7206	1.45395359045e-25
ko04727	GABAergic synapse	57/860	110/7206	8.17938923916e-25
ko04728	Dopaminergic synapse	75/860	185/7206	9.41325442526e-24
ko04723	Retrograde endocannabinoid signaling	69/860	175/7206	4.20558445495e-21
ko04725	Cholinergic synapse	63/860	160/7206	2.57952296891e-19
ko04024	cAMP signaling pathway	85/860	279/7206	2.38400629262e-17
ko04921	Oxytocin signaling pathway	69/860	209/7206	2.97456798254e-16
ko04911	Insulin secretion	48/860	117/7206	8.05369309851e-16
ko04721	Synaptic vesicle cycle	38/860	80/7206	2.66619663286e-15
ko04261	Adrenergic signaling in cardiomyocytes	66/860	205/7206	5.5525258556e-15
ko04020	Calcium signaling pathway	78/860	265/7206	5.81399144066e-15
ko05031	Amphetamine addiction	39/860	91/7206	7.88583869974e-14
ko04720	Long-term potentiation	38/860	99/7206	1.00851330226e-11
ko04726	Serotonergic synapse	46/860	137/7206	1.639375512e-11
ko04742	Taste transduction	27/860	61/7206	2.30871279059e-10
ko04925	Aldosterone synthesis and secretion	36/860	105/7206	1.42470311587e-09
ko04010	MAPK signaling pathway	75/860	321/7206	5.23410261114e-09
ko05030	Cocaine addiction	27/860	73/7206	2.63579356004e-08
ko04971	Gastric acid secretion	32/860	98/7206	4.47343873644e-08
ko04970	Salivary secretion	31/860	95/7206	7.39561119992e-08
ko03040	Spliceosome	1/860	145/7206	3.57484092556e-07
ko04360	Axon guidance	54/860	233/7206	9.27627507149e-07
ko04072	Phospholipase D signaling pathway	47/860	197/7206	1.95709810775e-06
ko04745	Phototransduction - fly	16/860	38/7206	2.55825047621e-06
ko04972	Pancreatic secretion	31/860	111/7206	4.030727874e-06
ko04060	Cytokine-cytokine receptor interaction	5/860	191/7206	4.28760984792e-06
ko04022	cGMP-PKG signaling pathway	49/860	216/7206	5.73220121073e-06
ko04744	Phototransduction	15/860	36/7206	6.17722482746e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/860	79/7206	8.97288910461e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	23/860	74/7206	9.02487092482e-06
ko04260	Cardiac muscle contraction	28/860	98/7206	9.7409433217e-06
ko05203	Viral carcinogenesis	12/860	277/7206	1.1648777083e-05
ko05414	Dilated cardiomyopathy	29/860	112/7206	4.32727715948e-05
ko04915	Estrogen signaling pathway	32/860	131/7206	5.62572072843e-05
ko05322	Systemic lupus erythematosus	4/860	151/7206	6.3466873176e-05
ko03013	RNA transport	5/860	166/7206	7.92775728162e-05
ko04730	Long-term depression	22/860	78/7206	0.000121499206858
ko04740	Olfactory transduction	22/860	80/7206	0.000149218273959
ko04621	NOD-like receptor signaling pathway	5/860	157/7206	0.000152396974514
ko04514	Cell adhesion molecules (CAMs)	31/860	130/7206	0.000164191835869
ko05168	Herpes simplex infection	7/860	182/7206	0.000181454424617
ko04750	Inflammatory mediator regulation of TRP channels	29/860	122/7206	0.000202122327589
ko04014	Ras signaling pathway	54/860	279/7206	0.000304663972155
ko04070	Phosphatidylinositol signaling system	27/860	112/7206	0.000307425426335
ko04141	Protein processing in endoplasmic reticulum	8/860	184/7206	0.000493249414526
ko03008	Ribosome biogenesis in eukaryotes	1/860	79/7206	0.000756942655696
ko05410	Hypertrophic cardiomyopathy (HCM)	24/860	100/7206	0.000835843192969
ko05164	Influenza A	7/860	167/7206	0.000955837650359
ko04924	Renin secretion	21/860	86/7206	0.00113657751947
ko04120	Ubiquitin mediated proteolysis	5/860	138/7206	0.00123466302713
ko04540	Gap junction	28/860	128/7206	0.00131458952979
ko04966	Collecting duct acid secretion	9/860	26/7206	0.00222653235273
ko04015	Rap1 signaling pathway	50/860	278/7206	0.00244788559577
ko04214	Apoptosis - fly	1/860	72/7206	0.00267023695236
ko05110	Vibrio cholerae infection	16/860	63/7206	0.00268062993822
ko04922	Glucagon signaling pathway	27/860	128/7206	0.00338558094488
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/860	14/7206	0.00365100533621
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/860	59/7206	0.00369358371717
ko04064	NF-kappa B signaling pathway	3/860	96/7206	0.00389600575334
ko05169	Epstein-Barr virus infection	12/860	206/7206	0.00434228225546
ko04930	Type II diabetes mellitus	14/860	54/7206	0.00454973931036
ko04640	Hematopoietic cell lineage	1/860	64/7206	0.0055631707505
ko04110	Cell cycle	7/860	145/7206	0.00602799926336
ko05140	Leishmaniasis	2/860	75/7206	0.00692773864401
ko04612	Antigen processing and presentation	2/860	77/7206	0.00702773647425
ko00330	Arginine and proline metabolism	1/860	61/7206	0.00832541385073
ko04371	Apelin signaling pathway	33/860	177/7206	0.00922746484146
ko04114	Oocyte meiosis	27/860	139/7206	0.0112110541676
ko00240	Pyrimidine metabolism	5/860	110/7206	0.0114147595553
ko05215	Prostate cancer	5/860	111/7206	0.0114531022334
ko00480	Glutathione metabolism	1/860	55/7206	0.0118587018099
ko04630	Jak-STAT signaling pathway	7/860	132/7206	0.0142408200427
ko04710	Circadian rhythm	11/860	43/7206	0.0144456835816
ko04626	Plant-pathogen interaction	6/860	18/7206	0.0148550594482
ko05205	Proteoglycans in cancer	20/860	271/7206	0.0166785671603
ko04918	Thyroid hormone synthesis	18/860	86/7206	0.0173928905885
ko04722	Neurotrophin signaling pathway	29/860	160/7206	0.018804516986
ko05161	Hepatitis B	11/860	173/7206	0.0231882310822
ko04912	GnRH signaling pathway	23/860	122/7206	0.0234441492571
ko04960	Aldosterone-regulated sodium reabsorption	10/860	41/7206	0.0250586397094
ko04210	Apoptosis	12/860	180/7206	0.0263301707967
ko04973	Carbohydrate digestion and absorption	10/860	42/7206	0.0278929798979
ko04330	Notch signaling pathway	2/860	62/7206	0.0291977793644
ko04146	Peroxisome	4/860	89/7206	0.0305280533424
ko04510	Focal adhesion	18/860	240/7206	0.0327934920322
ko05162	Measles	7/860	120/7206	0.0332844265676
ko04217	Necroptosis	12/860	178/7206	0.0340447042123
ko04976	Bile secretion	16/860	80/7206	0.0354021255267
ko05010	Alzheimer's disease	34/860	202/7206	0.035869853345
ko04071	Sphingolipid signaling pathway	28/860	162/7206	0.0374033209856
ko00071	Fatty acid degradation	1/860	45/7206	0.0375562365245
ko03420	Nucleotide excision repair	1/860	46/7206	0.0377572249041
ko04550	Signaling pathways regulating pluripotency of stem cells	11/860	165/7206	0.0378166078274
ko00270	Cysteine and methionine metabolism	1/860	47/7206	0.0385212820389
ko05219	Bladder cancer	1/860	48/7206	0.0398472839015
ko05231	Choline metabolism in cancer	24/860	134/7206	0.0421677868232
ko00310	Lysine degradation	3/860	73/7206	0.0431753877923