ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	190/1148	423/7206	1.83504617802e-48
ko05033	Nicotine addiction	49/1148	56/7206	2.50788617638e-32
ko04724	Glutamatergic synapse	87/1148	152/7206	5.36629069089e-32
ko04727	GABAergic synapse	69/1148	110/7206	5.68579707357e-29
ko05032	Morphine addiction	68/1148	110/7206	5.22866491323e-28
ko04713	Circadian entrainment	71/1148	136/7206	5.03258879935e-23
ko04721	Synaptic vesicle cycle	50/1148	80/7206	3.45140528773e-21
ko04728	Dopaminergic synapse	82/1148	185/7206	1.74224695521e-20
ko04723	Retrograde endocannabinoid signaling	79/1148	175/7206	2.25567791256e-20
ko04725	Cholinergic synapse	73/1148	160/7206	3.13458558446e-19
ko04742	Taste transduction	37/1148	61/7206	2.17659067921e-15
ko04744	Phototransduction	27/1148	36/7206	4.8333240034e-15
ko04024	cAMP signaling pathway	96/1148	279/7206	9.19465121956e-15
ko04726	Serotonergic synapse	57/1148	137/7206	3.84227534042e-13
ko04020	Calcium signaling pathway	89/1148	265/7206	5.15316046155e-13
ko04911	Insulin secretion	51/1148	117/7206	7.82705838213e-13
ko04740	Olfactory transduction	38/1148	80/7206	2.91024827349e-11
ko04261	Adrenergic signaling in cardiomyocytes	70/1148	205/7206	8.34796149886e-11
ko04921	Oxytocin signaling pathway	70/1148	209/7206	2.64284114626e-10
ko03040	Spliceosome	1/1148	145/7206	5.22000109765e-10
ko05031	Amphetamine addiction	37/1148	91/7206	1.15560792074e-08
ko05203	Viral carcinogenesis	14/1148	277/7206	2.03597123559e-08
ko04970	Salivary secretion	37/1148	95/7206	4.51233759515e-08
ko04720	Long-term potentiation	37/1148	99/7206	1.88894541235e-07
ko05030	Cocaine addiction	29/1148	73/7206	7.93607991578e-07
ko05322	Systemic lupus erythematosus	5/1148	151/7206	1.37289844614e-06
ko04925	Aldosterone synthesis and secretion	36/1148	105/7206	2.80558100438e-06
ko03013	RNA transport	7/1148	166/7206	2.81479053309e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1148	74/7206	6.30259190591e-06
ko05168	Herpes simplex infection	9/1148	182/7206	7.36518224076e-06
ko04966	Collecting duct acid secretion	14/1148	26/7206	9.14297526702e-06
ko05164	Influenza A	8/1148	167/7206	1.35648340532e-05
ko04971	Gastric acid secretion	33/1148	98/7206	1.74996302693e-05
ko04060	Cytokine-cytokine receptor interaction	11/1148	191/7206	2.11290385145e-05
ko04514	Cell adhesion molecules (CAMs)	39/1148	130/7206	4.85816099248e-05
ko04022	cGMP-PKG signaling pathway	57/1148	216/7206	6.33033598218e-05
ko04972	Pancreatic secretion	34/1148	111/7206	0.000108385026981
ko04072	Phospholipase D signaling pathway	52/1148	197/7206	0.000150269939481
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1148	79/7206	0.000152699734023
ko05205	Proteoglycans in cancer	22/1148	271/7206	0.000177084389308
ko05161	Hepatitis B	11/1148	173/7206	0.000199598412099
ko04610	Complement and coagulation cascades	2/1148	79/7206	0.000268956335388
ko03008	Ribosome biogenesis in eukaryotes	2/1148	79/7206	0.000268956335388
ko04360	Axon guidance	58/1148	233/7206	0.000348939230533
ko05162	Measles	6/1148	120/7206	0.000356305202646
ko04621	NOD-like receptor signaling pathway	10/1148	157/7206	0.00037708287069
ko04120	Ubiquitin mediated proteolysis	8/1148	138/7206	0.000380674926161
ko05140	Leishmaniasis	2/1148	75/7206	0.000387701555088
ko04745	Phototransduction - fly	15/1148	38/7206	0.000403222399377
ko04010	MAPK signaling pathway	75/1148	321/7206	0.000415510284638
ko04730	Long-term depression	25/1148	78/7206	0.000444865812748
ko04141	Protein processing in endoplasmic reticulum	13/1148	184/7206	0.000461695895381
ko04110	Cell cycle	9/1148	145/7206	0.000524709391094
ko04976	Bile secretion	25/1148	80/7206	0.000562237671775
ko05169	Epstein-Barr virus infection	16/1148	206/7206	0.000661311614736
ko04260	Cardiac muscle contraction	29/1148	98/7206	0.000679814871931
ko05110	Vibrio cholerae infection	21/1148	63/7206	0.000704304012877
ko04146	Peroxisome	4/1148	89/7206	0.00121514751795
ko00520	Amino sugar and nucleotide sugar metabolism	1/1148	55/7206	0.00132797333719
ko00480	Glutathione metabolism	1/1148	55/7206	0.00132797333719
ko04612	Antigen processing and presentation	3/1148	77/7206	0.00153401459136
ko05414	Dilated cardiomyopathy	31/1148	112/7206	0.00154742572159
ko04070	Phosphatidylinositol signaling system	31/1148	112/7206	0.00154742572159
ko04924	Renin secretion	25/1148	86/7206	0.00171316000134
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/1148	59/7206	0.00183365707404
ko04064	NF-kappa B signaling pathway	5/1148	96/7206	0.00185123921712
ko00590	Arachidonic acid metabolism	1/1148	52/7206	0.00199688639907
ko04640	Hematopoietic cell lineage	2/1148	64/7206	0.00286016500575
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1148	14/7206	0.00312233421767
ko04964	Proximal tubule bicarbonate reclamation	11/1148	29/7206	0.00343998773729
ko00240	Pyrimidine metabolism	7/1148	110/7206	0.00361092069889
ko04540	Gap junction	33/1148	128/7206	0.00464509308212
ko04915	Estrogen signaling pathway	33/1148	131/7206	0.00536854104452
ko03022	Basal transcription factors	1/1148	44/7206	0.00676899450754
ko04140	Autophagy - animal	14/1148	164/7206	0.0067855638983
ko05144	Malaria	1/1148	45/7206	0.00679913090904
ko00071	Fatty acid degradation	1/1148	45/7206	0.00679913090904
ko04658	Th1 and Th2 cell differentiation	6/1148	96/7206	0.00703729593205
ko03420	Nucleotide excision repair	1/1148	46/7206	0.00706585914166
ko05133	Pertussis	5/1148	87/7206	0.00722513134107
ko05321	Inflammatory bowel disease (IBD)	2/1148	56/7206	0.00885209123843
ko00310	Lysine degradation	4/1148	73/7206	0.00978142489029
ko04115	p53 signaling pathway	4/1148	74/7206	0.00983395624827
ko05166	HTLV-I infection	31/1148	292/7206	0.0111251224278
ko04923	Regulation of lipolysis in adipocytes	21/1148	77/7206	0.0111602156882
ko04750	Inflammatory mediator regulation of TRP channels	30/1148	122/7206	0.0120970665444
ko04210	Apoptosis	17/1148	180/7206	0.0132657697019
ko04622	RIG-I-like receptor signaling pathway	3/1148	62/7206	0.0134989211755
ko04657	IL-17 signaling pathway	6/1148	87/7206	0.0177091699916
ko05410	Hypertrophic cardiomyopathy (HCM)	25/1148	100/7206	0.0184182073509
ko04710	Circadian rhythm	13/1148	43/7206	0.0187809345002
ko04218	Cellular senescence	17/1148	177/7206	0.0215090000998
ko03410	Base excision repair	1/1148	38/7206	0.0232550520093
ko04932	Non-alcoholic fatty liver disease (NAFLD)	18/1148	182/7206	0.0235865467236
ko03018	RNA degradation	6/1148	84/7206	0.0239433899578
ko05145	Toxoplasmosis	11/1148	126/7206	0.0262668376971
ko00260	Glycine, serine and threonine metabolism	2/1148	48/7206	0.0268040363562
ko05219	Bladder cancer	2/1148	48/7206	0.0268040363562
ko04620	Toll-like receptor signaling pathway	8/1148	100/7206	0.0271600249892
ko04371	Apelin signaling pathway	39/1148	177/7206	0.0287915939788
ko04630	Jak-STAT signaling pathway	12/1148	132/7206	0.0301019371176
ko04510	Focal adhesion	26/1148	240/7206	0.0308048247793
ko05131	Shigellosis	6/1148	82/7206	0.0324425098964
ko04137	Mitophagy - animal	6/1148	82/7206	0.0324425098964
ko00860	Porphyrin and chlorophyll metabolism	1/1148	34/7206	0.0334920002845
ko04214	Apoptosis - fly	5/1148	72/7206	0.0346588012256
ko00280	Valine, leucine and isoleucine degradation	3/1148	54/7206	0.0380762837737
ko04810	Regulation of actin cytoskeleton	30/1148	264/7206	0.0395088999779
ko04711	Circadian rhythm - fly	5/1148	13/7206	0.0429570108037
ko05202	Transcriptional misregulation in cancer	20/1148	188/7206	0.0434465534776
ko04014	Ras signaling pathway	57/1148	279/7206	0.0447305548441
ko03320	PPAR signaling pathway	5/1148	69/7206	0.0469630190463
ko05215	Prostate cancer	10/1148	111/7206	0.0488757534835