ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	149/917	423/7206	4.50530780481e-35
ko04724	Glutamatergic synapse	82/917	152/7206	5.85158198777e-35
ko05033	Nicotine addiction	43/917	56/7206	4.79077600003e-28
ko05032	Morphine addiction	61/917	110/7206	4.414536759e-27
ko04727	GABAergic synapse	57/917	110/7206	2.23746605005e-23
ko04713	Circadian entrainment	63/917	136/7206	2.49205738616e-22
ko04728	Dopaminergic synapse	74/917	185/7206	2.67223975611e-21
ko04723	Retrograde endocannabinoid signaling	69/917	175/7206	1.63735423717e-19
ko04725	Cholinergic synapse	59/917	160/7206	2.95453703305e-15
ko04721	Synaptic vesicle cycle	39/917	80/7206	3.34820637164e-15
ko04024	cAMP signaling pathway	84/917	279/7206	4.75175320813e-15
ko04020	Calcium signaling pathway	80/917	265/7206	2.08564245339e-14
ko04726	Serotonergic synapse	51/917	137/7206	1.54498922093e-13
ko04911	Insulin secretion	45/917	117/7206	1.12734667677e-12
ko05031	Amphetamine addiction	38/917	91/7206	3.40671384607e-12
ko04720	Long-term potentiation	39/917	99/7206	1.55893077018e-11
ko04921	Oxytocin signaling pathway	60/917	209/7206	5.03904254969e-10
ko04744	Phototransduction	20/917	36/7206	1.00005260923e-09
ko04070	Phosphatidylinositol signaling system	39/917	112/7206	1.17111134665e-09
ko04261	Adrenergic signaling in cardiomyocytes	57/917	205/7206	6.34265518315e-09
ko04742	Taste transduction	25/917	61/7206	2.82308593563e-08
ko03040	Spliceosome	1/917	145/7206	9.10597228919e-08
ko05030	Cocaine addiction	27/917	73/7206	1.03021525404e-07
ko04925	Aldosterone synthesis and secretion	34/917	105/7206	1.07210883051e-07
ko04970	Salivary secretion	31/917	95/7206	3.21910035397e-07
ko04010	MAPK signaling pathway	73/917	321/7206	4.70217878316e-07
ko03010	Ribosome	1/917	129/7206	7.16798911966e-07
ko04730	Long-term depression	26/917	78/7206	1.82136192245e-06
ko05203	Viral carcinogenesis	12/917	277/7206	2.1585463687e-06
ko04072	Phospholipase D signaling pathway	48/917	197/7206	6.02916429534e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/917	74/7206	7.75689798192e-06
ko04971	Gastric acid secretion	29/917	98/7206	8.54930834439e-06
ko04972	Pancreatic secretion	31/917	111/7206	1.70173554609e-05
ko05164	Influenza A	5/917	167/7206	1.70396963155e-05
ko04110	Cell cycle	4/917	145/7206	4.13497660829e-05
ko04514	Cell adhesion molecules (CAMs)	33/917	130/7206	8.17587262615e-05
ko04060	Cytokine-cytokine receptor interaction	8/917	191/7206	9.49733473074e-05
ko05322	Systemic lupus erythematosus	5/917	151/7206	0.000101821391692
ko04022	cGMP-PKG signaling pathway	48/917	216/7206	0.000102753249183
ko05169	Epstein-Barr virus infection	10/917	206/7206	0.000184538156274
ko04621	NOD-like receptor signaling pathway	6/917	157/7206	0.00022831109536
ko05168	Herpes simplex infection	8/917	182/7206	0.000258668318149
ko04750	Inflammatory mediator regulation of TRP channels	30/917	122/7206	0.000288610498697
ko04014	Ras signaling pathway	56/917	279/7206	0.000449435459404
ko04745	Phototransduction - fly	13/917	38/7206	0.000531718727553
ko04612	Antigen processing and presentation	1/917	77/7206	0.00077344877019
ko03013	RNA transport	8/917	166/7206	0.000883042885154
ko04260	Cardiac muscle contraction	24/917	98/7206	0.00117144648033
ko04915	Estrogen signaling pathway	30/917	131/7206	0.00126294708945
ko04141	Protein processing in endoplasmic reticulum	10/917	184/7206	0.00154970215956
ko04360	Axon guidance	46/917	233/7206	0.00187232920182
ko00562	Inositol phosphate metabolism	22/917	89/7206	0.00190312697678
ko04964	Proximal tubule bicarbonate reclamation	10/917	29/7206	0.00216711973719
ko04740	Olfactory transduction	20/917	80/7206	0.00218362161301
ko04540	Gap junction	28/917	128/7206	0.00310944513693
ko04966	Collecting duct acid secretion	9/917	26/7206	0.00348285878048
ko05231	Choline metabolism in cancer	29/917	134/7206	0.00361373450024
ko04960	Aldosterone-regulated sodium reabsorption	12/917	41/7206	0.00388910664098
ko04120	Ubiquitin mediated proteolysis	7/917	138/7206	0.00421608196475
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/917	14/7206	0.0050616429757
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/917	79/7206	0.0056126607217
ko00240	Pyrimidine metabolism	5/917	110/7206	0.00586408187348
ko04930	Type II diabetes mellitus	14/917	54/7206	0.0069423106223
ko00480	Glutathione metabolism	1/917	55/7206	0.00777406464454
ko04630	Jak-STAT signaling pathway	7/917	132/7206	0.00778726637073
ko05162	Measles	6/917	120/7206	0.00804389166004
ko04924	Renin secretion	20/917	86/7206	0.00806050620322
ko04973	Carbohydrate digestion and absorption	12/917	42/7206	0.00806198707033
ko04710	Circadian rhythm	12/917	43/7206	0.00876005037917
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/917	59/7206	0.00886765861789
ko05217	Basal cell carcinoma	2/917	68/7206	0.0096639791208
ko00590	Arachidonic acid metabolism	1/917	52/7206	0.0114866450878
ko04071	Sphingolipid signaling pathway	32/917	162/7206	0.0115925782305
ko04217	Necroptosis	12/917	178/7206	0.012078685325
ko04918	Thyroid hormone synthesis	19/917	86/7206	0.0137090010343
ko04146	Peroxisome	4/917	89/7206	0.0154436788292
ko04610	Complement and coagulation cascades	3/917	79/7206	0.0157711276676
ko03008	Ribosome biogenesis in eukaryotes	3/917	79/7206	0.0157711276676
ko04015	Rap1 signaling pathway	49/917	278/7206	0.0166315829585
ko04550	Signaling pathways regulating pluripotency of stem cells	11/917	165/7206	0.0173978113089
ko00330	Arginine and proline metabolism	2/917	61/7206	0.0199175166257
ko04626	Plant-pathogen interaction	6/917	18/7206	0.0200146620882
ko05161	Hepatitis B	12/917	173/7206	0.0202207091861
ko04064	NF-kappa B signaling pathway	5/917	96/7206	0.0206913707072
ko05414	Dilated cardiomyopathy	23/917	112/7206	0.0208726020793
ko03420	Nucleotide excision repair	1/917	46/7206	0.0250222994525
ko05200	Pathways in cancer	47/917	492/7206	0.0295730951161
ko05166	HTLV-I infection	25/917	292/7206	0.0309374250126
ko05205	Proteoglycans in cancer	23/917	271/7206	0.0323103132404
ko05110	Vibrio cholerae infection	14/917	63/7206	0.0341560722582
ko03022	Basal transcription factors	1/917	44/7206	0.0376072891401
ko04510	Focal adhesion	20/917	240/7206	0.0381770128577
ko00071	Fatty acid degradation	1/917	45/7206	0.0389730075919
ko04922	Glucagon signaling pathway	24/917	128/7206	0.0444950077326