ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	113/614	423/7206	1.06381006207e-30
ko04724	Glutamatergic synapse	58/614	152/7206	2.01855043206e-24
ko05033	Nicotine addiction	35/614	56/7206	3.60348387169e-24
ko04728	Dopaminergic synapse	58/614	185/7206	1.6049790525e-19
ko04727	GABAergic synapse	40/614	110/7206	2.70499223409e-16
ko04713	Circadian entrainment	44/614	136/7206	1.27603679891e-15
ko05032	Morphine addiction	39/614	110/7206	1.74112590555e-15
ko04721	Synaptic vesicle cycle	32/614	80/7206	1.19856518931e-14
ko04725	Cholinergic synapse	46/614	160/7206	4.14579217147e-14
ko04024	cAMP signaling pathway	63/614	279/7206	1.92111726081e-13
ko04723	Retrograde endocannabinoid signaling	47/614	175/7206	3.54562025268e-13
ko04911	Insulin secretion	33/614	117/7206	3.18875008402e-10
ko05030	Cocaine addiction	23/614	73/7206	1.61369061937e-08
ko05031	Amphetamine addiction	26/614	91/7206	1.85811611525e-08
ko04726	Serotonergic synapse	33/614	137/7206	2.50377617463e-08
ko04261	Adrenergic signaling in cardiomyocytes	42/614	205/7206	5.99504207791e-08
ko04514	Cell adhesion molecules (CAMs)	31/614	130/7206	8.56721677688e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	22/614	74/7206	1.0703568111e-07
ko04360	Axon guidance	45/614	233/7206	1.23075568658e-07
ko04742	Taste transduction	17/614	61/7206	8.01967291188e-06
ko04921	Oxytocin signaling pathway	37/614	209/7206	1.38134418801e-05
ko04020	Calcium signaling pathway	44/614	265/7206	1.43972520017e-05
ko04970	Salivary secretion	21/614	95/7206	3.62825088743e-05
ko03040	Spliceosome	1/614	145/7206	6.03266859509e-05
ko05203	Viral carcinogenesis	7/614	277/7206	6.11808949821e-05
ko04720	Long-term potentiation	21/614	99/7206	6.91512806264e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/614	79/7206	8.5354565521e-05
ko04010	MAPK signaling pathway	48/614	321/7206	8.91110970613e-05
ko04972	Pancreatic secretion	22/614	111/7206	0.000183062008097
ko04060	Cytokine-cytokine receptor interaction	4/614	191/7206	0.000326476570277
ko05164	Influenza A	3/614	167/7206	0.000386614957818
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/614	14/7206	0.000618151174218
ko05168	Herpes simplex infection	4/614	182/7206	0.000653666856928
ko04730	Long-term depression	16/614	78/7206	0.000734138291213
ko00240	Pyrimidine metabolism	1/614	110/7206	0.000917967570722
ko04120	Ubiquitin mediated proteolysis	2/614	138/7206	0.000949583072875
ko04022	cGMP-PKG signaling pathway	33/614	216/7206	0.00110873881203
ko05322	Systemic lupus erythematosus	3/614	151/7206	0.00164341146868
ko05205	Proteoglycans in cancer	10/614	271/7206	0.00250965375451
ko05162	Measles	2/614	120/7206	0.00268648780863
ko04621	NOD-like receptor signaling pathway	4/614	157/7206	0.00350599316957
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/614	59/7206	0.00354023425394
ko04260	Cardiac muscle contraction	17/614	98/7206	0.00503860015986
ko04971	Gastric acid secretion	17/614	98/7206	0.00503860015986
ko04930	Type II diabetes mellitus	11/614	54/7206	0.00508019268504
ko04014	Ras signaling pathway	37/614	279/7206	0.00601229384507
ko01200	Carbon metabolism	3/614	128/7206	0.00631437255444
ko04146	Peroxisome	1/614	89/7206	0.00635456941453
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/614	15/7206	0.00644484596398
ko04140	Autophagy - animal	5/614	164/7206	0.00688268666765
ko03013	RNA transport	5/614	166/7206	0.00694287361145
ko04137	Mitophagy - animal	1/614	82/7206	0.00913690188481
ko04915	Estrogen signaling pathway	20/614	131/7206	0.0103098202137
ko04612	Antigen processing and presentation	1/614	77/7206	0.0133451785979
ko03008	Ribosome biogenesis in eukaryotes	1/614	79/7206	0.0134502974693
ko04540	Gap junction	19/614	128/7206	0.0154668537413
ko04150	mTOR signaling pathway	7/614	184/7206	0.0157523884234
ko04141	Protein processing in endoplasmic reticulum	7/614	184/7206	0.0157523884234
ko05414	Dilated cardiomyopathy	17/614	112/7206	0.0162846337417
ko05166	HTLV-I infection	14/614	292/7206	0.0180942170807
ko00310	Lysine degradation	1/614	73/7206	0.01942615454
ko04966	Collecting duct acid secretion	6/614	26/7206	0.0196487668735
ko04925	Aldosterone synthesis and secretion	16/614	105/7206	0.020412582396
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/614	182/7206	0.0211553140756
ko04110	Cell cycle	5/614	145/7206	0.0233568967113
ko00513	Various types of N-glycan biosynthesis	8/614	42/7206	0.0234251111087
ko04973	Carbohydrate digestion and absorption	8/614	42/7206	0.0234251111087
ko04962	Vasopressin-regulated water reabsorption	10/614	58/7206	0.0288751438094
ko04214	Apoptosis - fly	1/614	72/7206	0.0299867335958
ko05169	Epstein-Barr virus infection	9/614	206/7206	0.0303490401761
ko00512	Mucin type O-glycan biosynthesis	6/614	29/7206	0.0326411110918
ko04964	Proximal tubule bicarbonate reclamation	6/614	29/7206	0.0326411110918
ko05161	Hepatitis B	7/614	173/7206	0.0370199655947
ko04072	Phospholipase D signaling pathway	25/614	197/7206	0.0383372402107
ko04745	Phototransduction - fly	7/614	38/7206	0.0389347469322
ko00561	Glycerolipid metabolism	1/614	63/7206	0.0409789694555
ko04640	Hematopoietic cell lineage	1/614	64/7206	0.0410868441913
ko05034	Alcoholism	29/614	238/7206	0.0445005284262
ko03018	RNA degradation	2/614	84/7206	0.0460736978815
ko04350	TGF-beta signaling pathway	3/614	103/7206	0.0473871396658
ko04068	FoxO signaling pathway	7/614	167/7206	0.047873883794