ko pathway ratio_in_study ratio_in_pop p_value ko04144 Endocytosis 24/158 342/7206 3.38277799694e-07 ko04360 Axon guidance 15/158 233/7206 0.000168676372 ko04010 MAPK signaling pathway 18/158 321/7206 0.000215545382591 ko04914 Progesterone-mediated oocyte maturation 9/158 104/7206 0.000432725002916 ko04391 Hippo signaling pathway - fly 8/158 90/7206 0.000755786115967 ko04668 TNF signaling pathway 9/158 120/7206 0.00122283283515 ko04520 Adherens junction 8/158 103/7206 0.00182396798342 ko05212 Pancreatic cancer 7/158 83/7206 0.00219293132098 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 4/158 26/7206 0.00228288385797 ko04211 Longevity regulating pathway 8/158 123/7206 0.00547034969726 ko01522 Endocrine resistance 8/158 124/7206 0.00574137329609 ko04930 Type II diabetes mellitus 5/158 54/7206 0.00633145477051 ko04664 Fc epsilon RI signaling pathway 6/158 77/7206 0.00664936228014 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 3/158 19/7206 0.00774285025699 ko04722 Neurotrophin signaling pathway 9/158 160/7206 0.00839532148329 ko04152 AMPK signaling pathway 9/158 161/7206 0.00872983799482 ko04380 Osteoclast differentiation 8/158 134/7206 0.00904841468187 ko04071 Sphingolipid signaling pathway 9/158 162/7206 0.0090744006931 ko04012 ErbB signaling pathway 7/158 109/7206 0.0098187973322 ko04068 FoxO signaling pathway 9/158 167/7206 0.0109544275725 ko04213 Longevity regulating pathway - multiple species 6/158 86/7206 0.011232588303 ko05210 Colorectal cancer 6/158 86/7206 0.011232588303 ko04917 Prolactin signaling pathway 6/158 87/7206 0.0118520718467 ko04910 Insulin signaling pathway 9/158 172/7206 0.0131135711739 ko05200 Pathways in cancer 19/158 492/7206 0.0153070266038 ko00515 Mannose type O-glycan biosynthesis 3/158 25/7206 0.0166999901507 ko04912 GnRH signaling pathway 7/158 122/7206 0.0174598278372 ko05211 Renal cell carcinoma 6/158 96/7206 0.0185477226671 ko04015 Rap1 signaling pathway 12/158 278/7206 0.0206806199088 ko04014 Ras signaling pathway 12/158 279/7206 0.0211198927351 ko04624 Toll and Imd signaling pathway 4/158 49/7206 0.0219471372376 ko04390 Hippo signaling pathway 9/158 188/7206 0.0221663382181 ko05142 Chagas disease (American trypanosomiasis) 7/158 130/7206 0.0238482907817 ko04350 TGF-beta signaling pathway 6/158 103/7206 0.0252778826247 ko04080 Neuroactive ligand-receptor interaction 3/158 423/7206 0.0254459410522 ko04140 Autophagy - animal 8/158 164/7206 0.0274378484106 ko05231 Choline metabolism in cancer 7/158 134/7206 0.027580599112 ko04550 Signaling pathways regulating pluripotency of stem cells 8/158 165/7206 0.0283177271528 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/158 135/7206 0.0285724383404 ko01521 EGFR tyrosine kinase inhibitor resistance 6/158 106/7206 0.028604262449 ko04931 Insulin resistance 7/158 137/7206 0.030628236096 ko05220 Chronic myeloid leukemia 5/158 85/7206 0.0383847808328 ko04072 Phospholipase D signaling pathway 9/158 197/7206 0.0408216565431 ko04510 Focal adhesion 10/158 240/7206 0.0422986832532 ko04911 Insulin secretion 6/158 117/7206 0.0432228810979 ko04920 Adipocytokine signaling pathway 5/158 89/7206 0.0453535562709 ko04330 Notch signaling pathway 4/158 62/7206 0.0465432724182 ko04913 Ovarian steroidogenesis 4/158 63/7206 0.0488832208049 ko04724 Glutamatergic synapse 7/158 152/7206 0.0492603729355