ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	44/452	145/7206	1.52860822754e-19
ko04110	Cell cycle	43/452	145/7206	1.07864359811e-18
ko03440	Homologous recombination	22/452	41/7206	1.71459872664e-16
ko03030	DNA replication	21/452	38/7206	3.78323309793e-16
ko04111	Cell cycle - yeast	31/452	90/7206	8.01318414901e-16
ko03460	Fanconi anemia pathway	20/452	51/7206	7.43018841285e-12
ko04080	Neuroactive ligand-receptor interaction	1/452	423/7206	3.09143275315e-11
ko04113	Meiosis - yeast	22/452	70/7206	1.08794625972e-10
ko03420	Nucleotide excision repair	17/452	46/7206	8.61022256372e-10
ko03430	Mismatch repair	12/452	22/7206	1.16925147857e-09
ko03008	Ribosome biogenesis in eukaryotes	21/452	79/7206	8.73512994888e-09
ko03013	RNA transport	30/452	166/7206	1.03446311872e-07
ko03410	Base excision repair	13/452	38/7206	2.49770262563e-07
ko04020	Calcium signaling pathway	1/452	265/7206	8.84484100549e-07
ko00240	Pyrimidine metabolism	20/452	110/7206	1.30884693805e-05
ko03018	RNA degradation	16/452	84/7206	5.3256683033e-05
ko04022	cGMP-PKG signaling pathway	2/452	216/7206	0.000158432052551
ko04921	Oxytocin signaling pathway	2/452	209/7206	0.000228805746456
ko04151	PI3K-Akt signaling pathway	9/452	390/7206	0.000342281390268
ko04114	Oocyte meiosis	20/452	139/7206	0.000498424160418
ko04024	cAMP signaling pathway	5/452	279/7206	0.000569680919106
ko04621	NOD-like receptor signaling pathway	1/452	157/7206	0.000694782208507
ko04152	AMPK signaling pathway	1/452	161/7206	0.000735673674484
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/452	182/7206	0.000991582817336
ko04728	Dopaminergic synapse	2/452	185/7206	0.00100977552615
ko04724	Glutamatergic synapse	1/452	152/7206	0.00102902716506
ko04723	Retrograde endocannabinoid signaling	2/452	175/7206	0.0014264601612
ko05322	Systemic lupus erythematosus	20/452	151/7206	0.00170641300258
ko04261	Adrenergic signaling in cardiomyocytes	3/452	205/7206	0.00179541033362
ko05166	HTLV-I infection	32/452	292/7206	0.00184110922869
ko04713	Circadian entrainment	1/452	136/7206	0.00339420702355
ko04060	Cytokine-cytokine receptor interaction	3/452	191/7206	0.00352015720948
ko05016	Huntington's disease	4/452	215/7206	0.00382001611585
ko04510	Focal adhesion	5/452	240/7206	0.00400181881404
ko04725	Cholinergic synapse	2/452	160/7206	0.00430307242
ko00190	Oxidative phosphorylation	1/452	127/7206	0.00471643745065
ko01200	Carbon metabolism	1/452	128/7206	0.00478454389198
ko03022	Basal transcription factors	8/452	44/7206	0.00539535201632
ko04144	Endocytosis	10/452	342/7206	0.00591241364845
ko05012	Parkinson's disease	2/452	155/7206	0.00628594682662
ko04914	Progesterone-mediated oocyte maturation	14/452	104/7206	0.00633291994595
ko04010	MAPK signaling pathway	9/452	321/7206	0.00636635860952
ko04668	TNF signaling pathway	1/452	120/7206	0.00682267216094
ko04062	Chemokine signaling pathway	4/452	201/7206	0.00725703551564
ko05010	Alzheimer's disease	4/452	202/7206	0.00731449699025
ko05414	Dilated cardiomyopathy	1/452	112/7206	0.00983331911566
ko04218	Cellular senescence	20/452	177/7206	0.0107353907475
ko05203	Viral carcinogenesis	28/452	277/7206	0.0110176261111
ko03450	Non-homologous end-joining	4/452	15/7206	0.0119762122216
ko04931	Insulin resistance	2/452	137/7206	0.0120258652799
ko04726	Serotonergic synapse	2/452	137/7206	0.0120258652799
ko04611	Platelet activation	3/452	163/7206	0.0132435197717
ko05152	Tuberculosis	4/452	187/7206	0.0136376884077
ko04727	GABAergic synapse	1/452	110/7206	0.0149859453483
ko05032	Morphine addiction	1/452	110/7206	0.0149859453483
ko04015	Rap1 signaling pathway	8/452	278/7206	0.0156785970569
ko04014	Ras signaling pathway	8/452	279/7206	0.0158011786394
ko05142	Chagas disease (American trypanosomiasis)	2/452	130/7206	0.0170014271079
ko04915	Estrogen signaling pathway	2/452	131/7206	0.0170317314174
ko04630	Jak-STAT signaling pathway	2/452	132/7206	0.0171185861209
ko04720	Long-term potentiation	1/452	99/7206	0.0206704096506
ko04260	Cardiac muscle contraction	1/452	98/7206	0.020686529383
ko05410	Hypertrophic cardiomyopathy (HCM)	1/452	100/7206	0.0207389688381
ko04922	Glucagon signaling pathway	2/452	128/7206	0.0247899437298
ko04142	Lysosome	3/452	151/7206	0.0256204571572
ko04970	Salivary secretion	1/452	95/7206	0.0303334498014
ko04974	Protein digestion and absorption	1/452	96/7206	0.0307182945847
ko04064	NF-kappa B signaling pathway	1/452	96/7206	0.0307182945847
ko05167	Kaposi's sarcoma-associated herpesvirus infection	5/452	191/7206	0.0329499335077
ko04750	Inflammatory mediator regulation of TRP channels	2/452	122/7206	0.0350941314766
ko05034	Alcoholism	23/452	238/7206	0.0397399710129
ko05205	Proteoglycans in cancer	9/452	271/7206	0.0402784994524
ko04924	Renin secretion	1/452	86/7206	0.0431090187449
ko04920	Adipocytokine signaling pathway	1/452	89/7206	0.0439721695621
ko00310	Lysine degradation	9/452	73/7206	0.0464873342074
ko04972	Pancreatic secretion	2/452	111/7206	0.0472472478812
ko04380	Osteoclast differentiation	3/452	134/7206	0.0476491440735
ko04115	p53 signaling pathway	9/452	74/7206	0.0489001204879