ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	149/766	423/7206	4.9943462899e-45
ko05033	Nicotine addiction	45/766	56/7206	2.28391624645e-34
ko04724	Glutamatergic synapse	72/766	152/7206	3.33400489094e-31
ko04727	GABAergic synapse	49/766	110/7206	4.52794576205e-20
ko05032	Morphine addiction	49/766	110/7206	4.52794576205e-20
ko04728	Dopaminergic synapse	65/766	185/7206	1.49480004649e-19
ko04725	Cholinergic synapse	58/766	160/7206	2.71623912869e-18
ko04723	Retrograde endocannabinoid signaling	60/766	175/7206	1.56804749427e-17
ko04721	Synaptic vesicle cycle	38/766	80/7206	5.38219472122e-17
ko04713	Circadian entrainment	50/766	136/7206	3.27451393736e-16
ko04024	cAMP signaling pathway	73/766	279/7206	7.70350835533e-14
ko04911	Insulin secretion	41/766	117/7206	1.05077761576e-12
ko04726	Serotonergic synapse	45/766	137/7206	1.12404969528e-12
ko04921	Oxytocin signaling pathway	57/766	209/7206	6.84771798328e-12
ko05031	Amphetamine addiction	32/766	91/7206	3.04650463733e-10
ko04020	Calcium signaling pathway	63/766	265/7206	3.47941459532e-10
ko04742	Taste transduction	25/766	61/7206	6.63008929338e-10
ko04261	Adrenergic signaling in cardiomyocytes	52/766	205/7206	1.11636998215e-09
ko04010	MAPK signaling pathway	68/766	321/7206	1.4268420196e-08
ko05030	Cocaine addiction	25/766	73/7206	5.01007518471e-08
ko04720	Long-term potentiation	30/766	99/7206	5.66431222319e-08
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/766	79/7206	2.88717766423e-07
ko04514	Cell adhesion molecules (CAMs)	34/766	130/7206	3.97280995084e-07
ko05203	Viral carcinogenesis	7/766	277/7206	4.14736992931e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	23/766	74/7206	1.23133857991e-06
ko04744	Phototransduction	15/766	36/7206	1.42447786754e-06
ko03040	Spliceosome	1/766	145/7206	2.0321567688e-06
ko04260	Cardiac muscle contraction	26/766	98/7206	6.96390459213e-06
ko05164	Influenza A	3/766	167/7206	1.82494829275e-05
ko04060	Cytokine-cytokine receptor interaction	5/766	191/7206	4.11627864028e-05
ko04360	Axon guidance	45/766	233/7206	5.38684693578e-05
ko05322	Systemic lupus erythematosus	3/766	151/7206	7.98560698256e-05
ko05168	Herpes simplex infection	5/766	182/7206	0.000122312819081
ko04970	Salivary secretion	23/766	95/7206	0.000132099992339
ko04730	Long-term depression	20/766	78/7206	0.000132257768166
ko04072	Phospholipase D signaling pathway	38/766	197/7206	0.000233052287266
ko04925	Aldosterone synthesis and secretion	24/766	105/7206	0.000299599327363
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/766	182/7206	0.000358597485488
ko03013	RNA transport	5/766	166/7206	0.000476747877047
ko05169	Epstein-Barr virus infection	8/766	206/7206	0.000530832589814
ko05410	Hypertrophic cardiomyopathy (HCM)	22/766	100/7206	0.000813887248211
ko05414	Dilated cardiomyopathy	24/766	112/7206	0.000894930535295
ko05166	HTLV-I infection	15/766	292/7206	0.000942085855184
ko04141	Protein processing in endoplasmic reticulum	7/766	184/7206	0.000982778751123
ko04022	cGMP-PKG signaling pathway	39/766	216/7206	0.00101406124038
ko04120	Ubiquitin mediated proteolysis	4/766	138/7206	0.00116303406201
ko04971	Gastric acid secretion	21/766	98/7206	0.00142952042219
ko05162	Measles	3/766	120/7206	0.0014492719885
ko04972	Pancreatic secretion	23/766	111/7206	0.00155645320978
ko04740	Olfactory transduction	18/766	80/7206	0.00162415032232
ko04070	Phosphatidylinositol signaling system	23/766	112/7206	0.00168565495259
ko05205	Proteoglycans in cancer	14/766	271/7206	0.00174152756737
ko04350	TGF-beta signaling pathway	2/766	103/7206	0.00177304562749
ko04110	Cell cycle	5/766	145/7206	0.00245350166298
ko04612	Antigen processing and presentation	1/766	77/7206	0.0026474615894
ko03008	Ribosome biogenesis in eukaryotes	1/766	79/7206	0.00268392893606
ko04621	NOD-like receptor signaling pathway	6/766	157/7206	0.00354492980907
ko04014	Ras signaling pathway	45/766	279/7206	0.00389061853413
ko04924	Renin secretion	18/766	86/7206	0.00419491806035
ko04966	Collecting duct acid secretion	8/766	26/7206	0.0042889995104
ko04140	Autophagy - animal	7/766	164/7206	0.00458407254631
ko04745	Phototransduction - fly	10/766	38/7206	0.00514857528214
ko04214	Apoptosis - fly	1/766	72/7206	0.00592044311435
ko00310	Lysine degradation	1/766	73/7206	0.00613526445654
ko05161	Hepatitis B	8/766	173/7206	0.0081207312618
ko04964	Proximal tubule bicarbonate reclamation	8/766	29/7206	0.00884625709027
ko04068	FoxO signaling pathway	8/766	167/7206	0.0105429215166
ko03018	RNA degradation	2/766	84/7206	0.0110395114728
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/766	14/7206	0.0118278775163
ko04930	Type II diabetes mellitus	12/766	54/7206	0.0120313479914
ko05215	Prostate cancer	4/766	111/7206	0.0120766089557
ko04330	Notch signaling pathway	1/766	62/7206	0.0124117408602
ko04540	Gap junction	23/766	128/7206	0.0127574611799
ko04550	Signaling pathways regulating pluripotency of stem cells	8/766	165/7206	0.014302728958
ko04630	Jak-STAT signaling pathway	6/766	132/7206	0.0213520166921
ko05140	Leishmaniasis	2/766	75/7206	0.0217400849825
ko05231	Choline metabolism in cancer	23/766	134/7206	0.0221856540782
ko04146	Peroxisome	3/766	89/7206	0.022830907667
ko05016	Huntington's disease	13/766	215/7206	0.0243431635096
ko00480	Glutathione metabolism	1/766	55/7206	0.0266550547949
ko00280	Valine, leucine and isoleucine degradation	1/766	54/7206	0.0266652513715
ko01200	Carbon metabolism	6/766	128/7206	0.0285201603951
ko04915	Estrogen signaling pathway	22/766	131/7206	0.0303670423814
ko05110	Vibrio cholerae infection	12/766	63/7206	0.0384483646096
ko04150	mTOR signaling pathway	11/766	184/7206	0.0386398669054
ko00240	Pyrimidine metabolism	5/766	110/7206	0.0407322211693
ko04064	NF-kappa B signaling pathway	4/766	96/7206	0.0431147115456