ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	89/675	145/7206	6.85048383341e-56
ko04110	Cell cycle	64/675	145/7206	7.83102210946e-29
ko03013	RNA transport	66/675	166/7206	1.75011389315e-26
ko04111	Cell cycle - yeast	47/675	90/7206	2.07203828664e-25
ko03030	DNA replication	29/675	38/7206	6.20263706581e-23
ko04113	Meiosis - yeast	32/675	70/7206	1.71874804052e-15
ko03440	Homologous recombination	24/675	41/7206	4.61596766847e-15
ko03015	mRNA surveillance pathway	36/675	93/7206	1.73400752896e-14
ko03430	Mismatch repair	16/675	22/7206	1.29732241783e-12
ko03420	Nucleotide excision repair	22/675	46/7206	1.54459554696e-11
ko03460	Fanconi anemia pathway	22/675	51/7206	1.94045124234e-10
ko04020	Calcium signaling pathway	1/675	265/7206	2.03233319701e-10
ko03018	RNA degradation	28/675	84/7206	8.93119622032e-10
ko03008	Ribosome biogenesis in eukaryotes	27/675	79/7206	9.49415459941e-10
ko03410	Base excision repair	18/675	38/7206	1.37848539442e-09
ko04144	Endocytosis	5/675	342/7206	1.51865231822e-09
ko00240	Pyrimidine metabolism	31/675	110/7206	1.13308897023e-08
ko04723	Retrograde endocannabinoid signaling	1/675	175/7206	1.05608498407e-06
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/675	182/7206	4.21816219594e-06
ko04724	Glutamatergic synapse	1/675	152/7206	7.65023795856e-06
ko04060	Cytokine-cytokine receptor interaction	3/675	191/7206	1.3588858867e-05
ko04921	Oxytocin signaling pathway	4/675	209/7206	1.80765524661e-05
ko04024	cAMP signaling pathway	8/675	279/7206	2.26935404614e-05
ko04120	Ubiquitin mediated proteolysis	29/675	138/7206	2.40974455765e-05
ko03022	Basal transcription factors	14/675	44/7206	2.79948751631e-05
ko05169	Epstein-Barr virus infection	38/675	206/7206	4.43593704919e-05
ko04022	cGMP-PKG signaling pathway	5/675	216/7206	4.50046530988e-05
ko05012	Parkinson's disease	2/675	155/7206	6.417930835e-05
ko05168	Herpes simplex infection	34/675	182/7206	8.05198822201e-05
ko03050	Proteasome	15/675	54/7206	8.60184458407e-05
ko03010	Ribosome	1/675	129/7206	8.71559018831e-05
ko04062	Chemokine signaling pathway	5/675	201/7206	0.00018303029941
ko05166	HTLV-I infection	47/675	292/7206	0.00019189251279
ko04810	Regulation of actin cytoskeleton	9/675	264/7206	0.000224239137737
ko04725	Cholinergic synapse	3/675	160/7206	0.00027143160148
ko04713	Circadian entrainment	2/675	136/7206	0.000281968123193
ko04726	Serotonergic synapse	2/675	137/7206	0.000285638444859
ko04911	Insulin secretion	1/675	117/7206	0.000292134940268
ko04270	Vascular smooth muscle contraction	3/675	154/7206	0.000374293691557
ko04727	GABAergic synapse	1/675	110/7206	0.000402609665844
ko04972	Pancreatic secretion	1/675	111/7206	0.000408729947319
ko04915	Estrogen signaling pathway	2/675	131/7206	0.000408798893352
ko05217	Basal cell carcinoma	16/675	68/7206	0.000416158871401
ko05414	Dilated cardiomyopathy	1/675	112/7206	0.000420079162219
ko04142	Lysosome	3/675	151/7206	0.000552211356747
ko04261	Adrenergic signaling in cardiomyocytes	6/675	205/7206	0.000553370665768
ko04114	Oocyte meiosis	26/675	139/7206	0.000559904155701
ko01200	Carbon metabolism	2/675	128/7206	0.000599260836487
ko04514	Cell adhesion molecules (CAMs)	2/675	130/7206	0.000629073568133
ko04010	MAPK signaling pathway	14/675	321/7206	0.000808562140107
ko04912	GnRH signaling pathway	2/675	122/7206	0.000860113483463
ko04371	Apelin signaling pathway	5/675	177/7206	0.000966066190587
ko04974	Protein digestion and absorption	1/675	96/7206	0.00129417079965
ko05410	Hypertrophic cardiomyopathy (HCM)	1/675	100/7206	0.00139125494911
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/675	135/7206	0.00153077626824
ko04380	Osteoclast differentiation	3/675	134/7206	0.00153227397788
ko05152	Tuberculosis	6/675	187/7206	0.00199270088601
ko04712	Circadian rhythm - plant	4/675	7/7206	0.00212042578436
ko04151	PI3K-Akt signaling pathway	20/675	390/7206	0.00225583623428
ko04218	Cellular senescence	29/675	177/7206	0.00245786384955
ko04611	Platelet activation	5/675	163/7206	0.00257260346782
ko00230	Purine metabolism	31/675	194/7206	0.00258678712016
ko05032	Morphine addiction	2/675	110/7206	0.00259674382022
ko04072	Phospholipase D signaling pathway	7/675	197/7206	0.00265679855123
ko04070	Phosphatidylinositol signaling system	2/675	112/7206	0.00268593264649
ko04662	B cell receptor signaling pathway	1/675	88/7206	0.00280336132747
ko04071	Sphingolipid signaling pathway	5/675	162/7206	0.00369392913849
ko04145	Phagosome	5/675	162/7206	0.00369392913849
ko04925	Aldosterone synthesis and secretion	2/675	105/7206	0.00372363212672
ko04659	Th17 cell differentiation	2/675	106/7206	0.00374754696958
ko03020	RNA polymerase	8/675	29/7206	0.00411415194232
ko04924	Renin secretion	1/675	86/7206	0.00425723343336
ko04015	Rap1 signaling pathway	13/675	278/7206	0.00437582822377
ko04910	Insulin signaling pathway	6/675	172/7206	0.00495378957106
ko04620	Toll-like receptor signaling pathway	2/675	100/7206	0.00534652815358
ko04976	Bile secretion	1/675	80/7206	0.00606512435078
ko04668	TNF signaling pathway	3/675	120/7206	0.00634003208402
ko04330	Notch signaling pathway	13/675	62/7206	0.00640507226291
ko05231	Choline metabolism in cancer	4/675	134/7206	0.00655194848419
ko04728	Dopaminergic synapse	7/675	185/7206	0.00666943341174
ko04650	Natural killer cell mediated cytotoxicity	2/675	97/7206	0.0076825576327
ko05132	Salmonella infection	2/675	98/7206	0.0077804191252
ko05146	Amoebiasis	2/675	99/7206	0.00794440670377
ko00564	Glycerophospholipid metabolism	2/675	99/7206	0.00794440670377
ko04540	Gap junction	4/675	128/7206	0.00905351982158
ko04923	Regulation of lipolysis in adipocytes	1/675	77/7206	0.0090633293523
ko05142	Chagas disease (American trypanosomiasis)	4/675	130/7206	0.00909532130824
ko04730	Long-term depression	1/675	78/7206	0.00930582426658
ko04914	Progesterone-mediated oocyte maturation	18/675	104/7206	0.00980566646406
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/675	92/7206	0.0109337177871
ko04660	T cell receptor signaling pathway	4/675	124/7206	0.0124689154806
ko05145	Toxoplasmosis	4/675	126/7206	0.0126016522798
ko05030	Cocaine addiction	1/675	73/7206	0.0133509121855
ko04657	IL-17 signaling pathway	2/675	87/7206	0.0155641804707
ko05323	Rheumatoid arthritis	2/675	89/7206	0.0157714719899
ko04920	Adipocytokine signaling pathway	2/675	89/7206	0.0157714719899
ko00562	Inositol phosphate metabolism	2/675	89/7206	0.0157714719899
ko05160	Hepatitis C	6/675	153/7206	0.0163250557396
ko04139	Mitophagy - yeast	8/675	37/7206	0.0190081714334
ko04014	Ras signaling pathway	15/675	279/7206	0.0204472016855
ko01230	Biosynthesis of amino acids	2/675	85/7206	0.0225389795743
ko04918	Thyroid hormone synthesis	2/675	86/7206	0.0230018536535
ko04115	p53 signaling pathway	13/675	74/7206	0.024599305307
ko04913	Ovarian steroidogenesis	1/675	63/7206	0.0277675397958
ko00561	Glycerolipid metabolism	1/675	63/7206	0.0277675397958
ko00600	Sphingolipid metabolism	1/675	63/7206	0.0277675397958
ko04510	Focal adhesion	13/675	240/7206	0.0317284443057
ko04138	Autophagy - yeast	2/675	81/7206	0.0321382799856
ko04931	Insulin resistance	6/675	137/7206	0.0383854309318
ko04212	Longevity regulating pathway - worm	14/675	87/7206	0.0398308558513
ko04962	Vasopressin-regulated water reabsorption	1/675	58/7206	0.040193523304
ko04750	Inflammatory mediator regulation of TRP channels	5/675	122/7206	0.0411237016327
ko04066	HIF-1 signaling pathway	5/675	123/7206	0.0412553465183
ko04140	Autophagy - animal	8/675	164/7206	0.0421733256773
ko05222	Small cell lung cancer	14/675	89/7206	0.0442111878458
ko05031	Amphetamine addiction	3/675	91/7206	0.0448669396738
ko04370	VEGF signaling pathway	2/675	77/7206	0.0456998120003
ko04670	Leukocyte transendothelial migration	7/675	151/7206	0.0467096784325