ko pathway ratio_in_study ratio_in_pop p_value ko04137 Mitophagy - animal 21/614 82/7206 3.13874018141e-06 ko00120 Primary bile acid biosynthesis 9/614 20/7206 1.5909749562e-05 ko04710 Circadian rhythm 13/614 43/7206 3.64615305426e-05 ko03010 Ribosome 1/614 129/7206 0.000193261198895 ko04070 Phosphatidylinositol signaling system 22/614 112/7206 0.000199021755216 ko03040 Spliceosome 2/614 145/7206 0.000431270911234 ko05150 Staphylococcus aureus infection 10/614 36/7206 0.00061907500547 ko00362 Benzoate degradation 4/614 6/7206 0.000681154793003 ko04630 Jak-STAT signaling pathway 23/614 132/7206 0.000782715077451 ko04136 Autophagy - other 9/614 31/7206 0.000812932786099 ko04068 FoxO signaling pathway 27/614 167/7206 0.00105686390666 ko00620 Pyruvate metabolism 11/614 46/7206 0.00132149647355 ko00051 Fructose and mannose metabolism 10/614 42/7206 0.00224773355717 ko00592 alpha-Linolenic acid metabolism 6/614 19/7206 0.00386024033678 ko03015 mRNA surveillance pathway 1/614 93/7206 0.00429687464434 ko00010 Glycolysis / Gluconeogenesis 14/614 74/7206 0.00475862070535 ko04390 Hippo signaling pathway 6/614 188/7206 0.00506124227506 ko04022 cGMP-PKG signaling pathway 30/614 216/7206 0.00635256909423 ko00680 Methane metabolism 8/614 34/7206 0.00657322197478 ko05321 Inflammatory bowel disease (IBD) 11/614 56/7206 0.00676550690274 ko03013 RNA transport 5/614 166/7206 0.00694287361145 ko04610 Complement and coagulation cascades 14/614 79/7206 0.00715477244535 ko04138 Autophagy - yeast 14/614 81/7206 0.00860328649076 ko04650 Natural killer cell mediated cytotoxicity 16/614 97/7206 0.00913162460686 ko04110 Cell cycle 4/614 145/7206 0.00961093108446 ko04146 Peroxisome 15/614 89/7206 0.0109271697234 ko05340 Primary immunodeficiency 7/614 30/7206 0.0113247499127 ko04151 PI3K-Akt signaling pathway 20/614 390/7206 0.0115834960274 ko05224 Breast cancer 6/614 174/7206 0.0125413493651 ko02010 ABC transporters 8/614 39/7206 0.0152851548805 ko01200 Carbon metabolism 19/614 128/7206 0.0154668537413 ko04922 Glucagon signaling pathway 19/614 128/7206 0.0154668537413 ko04140 Autophagy - animal 23/614 164/7206 0.0155134380961 ko01212 Fatty acid metabolism 11/614 60/7206 0.0160930011603 ko05322 Systemic lupus erythematosus 5/614 151/7206 0.0174171871154 ko05200 Pathways in cancer 28/614 492/7206 0.0188913056033 ko04621 NOD-like receptor signaling pathway 22/614 157/7206 0.0195410032959 ko00561 Glycerolipid metabolism 11/614 63/7206 0.0198484165353 ko04371 Apelin signaling pathway 24/614 177/7206 0.0200171935069 ko04711 Circadian rhythm - fly 4/614 13/7206 0.0200218577127 ko05203 Viral carcinogenesis 13/614 277/7206 0.0204230957788 ko05034 Alcoholism 11/614 238/7206 0.0247224662026 ko04380 Osteoclast differentiation 19/614 134/7206 0.027013191931 ko05217 Basal cell carcinoma 1/614 68/7206 0.0282400535102 ko04113 Meiosis - yeast 1/614 70/7206 0.0286876148996 ko01230 Biosynthesis of amino acids 13/614 85/7206 0.031293243234 ko04611 Platelet activation 22/614 163/7206 0.0316500723061 ko04391 Hippo signaling pathway - fly 2/614 90/7206 0.0334662579378 ko05145 Toxoplasmosis 18/614 126/7206 0.034069713151 ko04060 Cytokine-cytokine receptor interaction 25/614 191/7206 0.0341056883005 ko04672 Intestinal immune network for IgA production 7/614 37/7206 0.0341751951522 ko00982 Drug metabolism - cytochrome P450 7/614 37/7206 0.0341751951522 ko00380 Tryptophan metabolism 9/614 50/7206 0.0351146420927 ko04730 Long-term depression 12/614 78/7206 0.0390755083496 ko00590 Arachidonic acid metabolism 9/614 52/7206 0.0394488806496 ko04530 Tight junction 11/614 228/7206 0.040171422504 ko04921 Oxytocin signaling pathway 26/614 209/7206 0.0441586646533 ko04930 Type II diabetes mellitus 9/614 54/7206 0.0451511102169 ko05100 Bacterial invasion of epithelial cells 3/614 99/7206 0.0455632788975 ko03320 PPAR signaling pathway 11/614 69/7206 0.0459942746068 ko00072 Synthesis and degradation of ketone bodies 3/614 10/7206 0.0469498787303 ko04550 Signaling pathways regulating pluripotency of stem cells 7/614 165/7206 0.0472497088724 ko04350 TGF-beta signaling pathway 3/614 103/7206 0.0473871396658