ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	155/856	423/7206	6.63032270004e-43
ko04724	Glutamatergic synapse	79/856	152/7206	2.3380372342e-34
ko05033	Nicotine addiction	44/856	56/7206	9.85051455146e-31
ko04727	GABAergic synapse	58/856	110/7206	7.40863682463e-26
ko05032	Morphine addiction	56/856	110/7206	5.36168908239e-24
ko04713	Circadian entrainment	62/856	136/7206	3.76415899748e-23
ko04723	Retrograde endocannabinoid signaling	67/856	175/7206	8.27955440847e-20
ko04728	Dopaminergic synapse	68/856	185/7206	5.82772968664e-19
ko04744	Phototransduction	27/856	36/7206	2.35882662356e-18
ko04721	Synaptic vesicle cycle	41/856	80/7206	5.21755998938e-18
ko04725	Cholinergic synapse	60/856	160/7206	2.46211741299e-17
ko04742	Taste transduction	34/856	61/7206	1.26386378776e-16
ko04911	Insulin secretion	47/856	117/7206	3.58286283114e-15
ko04024	cAMP signaling pathway	80/856	279/7206	7.99746932698e-15
ko04726	Serotonergic synapse	51/856	137/7206	9.38561838416e-15
ko04020	Calcium signaling pathway	76/856	265/7206	3.94763544202e-14
ko04921	Oxytocin signaling pathway	62/856	209/7206	1.91567040526e-12
ko04740	Olfactory transduction	34/856	80/7206	3.73820390045e-12
ko04970	Salivary secretion	35/856	95/7206	2.23699709528e-10
ko04261	Adrenergic signaling in cardiomyocytes	57/856	205/7206	3.7114005011e-10
ko05031	Amphetamine addiction	33/856	91/7206	1.18740499055e-09
ko04720	Long-term potentiation	33/856	99/7206	1.37662288558e-08
ko05030	Cocaine addiction	26/856	73/7206	1.05746001438e-07
ko04971	Gastric acid secretion	31/856	98/7206	1.47919102618e-07
ko04972	Pancreatic secretion	33/856	111/7206	3.03443351648e-07
ko05203	Viral carcinogenesis	9/856	277/7206	3.42670226645e-07
ko03040	Spliceosome	1/856	145/7206	3.51031742757e-07
ko04120	Ubiquitin mediated proteolysis	1/856	138/7206	7.9245322251e-07
ko05164	Influenza A	3/856	167/7206	2.44328232886e-06
ko05162	Measles	1/856	120/7206	6.06308284161e-06
ko04060	Cytokine-cytokine receptor interaction	5/856	191/7206	6.47834924558e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	23/856	74/7206	8.34460109154e-06
ko04925	Aldosterone synthesis and secretion	29/856	105/7206	9.58201149105e-06
ko05322	Systemic lupus erythematosus	3/856	151/7206	1.09832992304e-05
ko04260	Cardiac muscle contraction	27/856	98/7206	2.10386355577e-05
ko04730	Long-term depression	23/856	78/7206	2.18741741343e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/856	79/7206	2.74586961024e-05
ko04010	MAPK signaling pathway	63/856	321/7206	4.21311980114e-05
ko04745	Phototransduction - fly	14/856	38/7206	6.19958116753e-05
ko05169	Epstein-Barr virus infection	8/856	206/7206	7.16258864287e-05
ko04540	Gap junction	31/856	128/7206	8.0994197671e-05
ko04750	Inflammatory mediator regulation of TRP channels	30/856	122/7206	9.21050642968e-05
ko04976	Bile secretion	22/856	80/7206	0.000143494755938
ko04621	NOD-like receptor signaling pathway	5/856	157/7206	0.000152510701509
ko04022	cGMP-PKG signaling pathway	45/856	216/7206	0.000153270105547
ko03013	RNA transport	6/856	166/7206	0.000237980864334
ko05168	Herpes simplex infection	7/856	182/7206	0.00026364698678
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/856	182/7206	0.00026364698678
ko05414	Dilated cardiomyopathy	27/856	112/7206	0.000295386975954
ko04924	Renin secretion	22/856	86/7206	0.000554363354284
ko04510	Focal adhesion	13/856	240/7206	0.000772033333435
ko04514	Cell adhesion molecules (CAMs)	29/856	130/7206	0.000831143885685
ko05215	Prostate cancer	3/856	111/7206	0.000947315245451
ko04612	Antigen processing and presentation	1/856	77/7206	0.00113267914064
ko05166	HTLV-I infection	18/856	292/7206	0.00117651049243
ko04964	Proximal tubule bicarbonate reclamation	10/856	29/7206	0.00127422967132
ko04141	Protein processing in endoplasmic reticulum	9/856	184/7206	0.00167338180196
ko05161	Hepatitis B	8/856	173/7206	0.00176371490857
ko04350	TGF-beta signaling pathway	3/856	103/7206	0.00192224640575
ko04966	Collecting duct acid secretion	9/856	26/7206	0.00215454734213
ko04072	Phospholipase D signaling pathway	38/856	197/7206	0.00235225110463
ko05110	Vibrio cholerae infection	16/856	63/7206	0.00258235460738
ko04214	Apoptosis - fly	1/856	72/7206	0.00263413301937
ko05205	Proteoglycans in cancer	17/856	271/7206	0.00282769427617
ko04140	Autophagy - animal	8/856	164/7206	0.00313940207041
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/856	59/7206	0.00357367428625
ko04064	NF-kappa B signaling pathway	3/856	96/7206	0.0038976591994
ko03008	Ribosome biogenesis in eukaryotes	2/856	79/7206	0.00480964560855
ko04110	Cell cycle	7/856	145/7206	0.0059709324415
ko04630	Jak-STAT signaling pathway	6/856	132/7206	0.00610245238281
ko04668	TNF signaling pathway	5/856	120/7206	0.00620831909768
ko04210	Apoptosis	10/856	180/7206	0.00680722415053
ko01524	Platinum drug resistance	2/856	76/7206	0.00693223931305
ko04070	Phosphatidylinositol signaling system	23/856	112/7206	0.00749000816668
ko05222	Small cell lung cancer	3/856	89/7206	0.00782002223954
ko04330	Notch signaling pathway	1/856	62/7206	0.00859521460415
ko00310	Lysine degradation	2/856	73/7206	0.0100015610006
ko05140	Leishmaniasis	2/856	75/7206	0.0104598448451
ko05220	Chronic myeloid leukemia	3/856	85/7206	0.0110264506979
ko05016	Huntington's disease	14/856	215/7206	0.013274128542
ko04626	Plant-pathogen interaction	6/856	18/7206	0.0145333763848
ko03018	RNA degradation	3/856	84/7206	0.0159590452689
ko00590	Arachidonic acid metabolism	1/856	52/7206	0.0174688225629
ko00280	Valine, leucine and isoleucine degradation	1/856	54/7206	0.017863803117
ko04218	Cellular senescence	11/856	177/7206	0.0178977136818
ko04014	Ras signaling pathway	46/856	279/7206	0.0182180732467
ko05410	Hypertrophic cardiomyopathy (HCM)	20/856	100/7206	0.0182369872899
ko00520	Amino sugar and nucleotide sugar metabolism	1/856	55/7206	0.01849431998
ko00480	Glutathione metabolism	1/856	55/7206	0.01849431998
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/856	14/7206	0.0186662603087
ko04550	Signaling pathways regulating pluripotency of stem cells	10/856	165/7206	0.0198346226487
ko04610	Complement and coagulation cascades	3/856	79/7206	0.0217929496537
ko04978	Mineral absorption	10/856	40/7206	0.0223670982619
ko05224	Breast cancer	11/856	174/7206	0.0232850721473
ko05145	Toxoplasmosis	7/856	126/7206	0.0253287378167
ko04915	Estrogen signaling pathway	24/856	131/7206	0.0283096636747
ko04657	IL-17 signaling pathway	4/856	87/7206	0.0299124129148
ko04115	p53 signaling pathway	3/856	74/7206	0.030309078453
ko04146	Peroxisome	4/856	89/7206	0.0303558788985
ko05200	Pathways in cancer	44/856	492/7206	0.036268565378
ko00240	Pyrimidine metabolism	6/856	110/7206	0.0363371407554
ko05144	Malaria	1/856	45/7206	0.0376418106623
ko00071	Fatty acid degradation	1/856	45/7206	0.0376418106623
ko00620	Pyruvate metabolism	1/856	46/7206	0.0377237406541
ko03420	Nucleotide excision repair	1/856	46/7206	0.0377237406541
ko04150	mTOR signaling pathway	13/856	184/7206	0.0378671434819
ko05211	Renal cell carcinoma	5/856	96/7206	0.0387061479416
ko05212	Pancreatic cancer	4/856	83/7206	0.0408929494366
ko05218	Melanoma	4/856	85/7206	0.0412288596731
ko04142	Lysosome	10/856	151/7206	0.0417783116798
ko05418	Fluid shear stress and atherosclerosis	12/856	173/7206	0.0425512386218
ko00330	Arginine and proline metabolism	2/856	61/7206	0.0433174896743
ko04062	Chemokine signaling pathway	33/856	201/7206	0.0468263198604