ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 9/47 120/7206 5.83264778187e-08 ko04621 NOD-like receptor signaling pathway 7/47 157/7206 6.16478139027e-05 ko04068 FoxO signaling pathway 7/47 167/7206 9.11837352429e-05 ko04912 GnRH signaling pathway 6/47 122/7206 0.000126733151924 ko04932 Non-alcoholic fatty liver disease (NAFLD) 7/47 182/7206 0.000156338997715 ko04060 Cytokine-cytokine receptor interaction 7/47 191/7206 0.000210883141219 ko04657 IL-17 signaling pathway 5/47 87/7206 0.000235181954247 ko04658 Th1 and Th2 cell differentiation 5/47 96/7206 0.000372398091358 ko04064 NF-kappa B signaling pathway 5/47 96/7206 0.000372398091358 ko05166 HTLV-I infection 8/47 292/7206 0.000522836963593 ko04217 Necroptosis 6/47 178/7206 0.000966794581932 ko04010 MAPK signaling pathway 8/47 321/7206 0.00097584336396 ko04210 Apoptosis 6/47 180/7206 0.00102472962703 ko05168 Herpes simplex infection 6/47 182/7206 0.00108530922783 ko04750 Inflammatory mediator regulation of TRP channels 5/47 122/7206 0.00111309258551 ko05152 Tuberculosis 6/47 187/7206 0.00124886060187 ko05142 Chagas disease (American trypanosomiasis) 5/47 130/7206 0.00147853830824 ko04380 Osteoclast differentiation 5/47 134/7206 0.0016913457294 ko05205 Proteoglycans in cancer 7/47 271/7206 0.00170342285577 ko04933 AGE-RAGE signaling pathway in diabetic complications 5/47 135/7206 0.00174789799262 ko04931 Insulin resistance 5/47 137/7206 0.00186516472332 ko05131 Shigellosis 4/47 82/7206 0.00191556520679 ko05212 Pancreatic cancer 4/47 83/7206 0.00200301511849 ko04662 B cell receptor signaling pathway 4/47 88/7206 0.00248211227565 ko04920 Adipocytokine signaling pathway 4/47 89/7206 0.00258660527993 ko05222 Small cell lung cancer 4/47 89/7206 0.00258660527993 ko05160 Hepatitis C 5/47 153/7206 0.00302180987196 ko04722 Neurotrophin signaling pathway 5/47 160/7206 0.00366391706594 ko05100 Bacterial invasion of epithelial cells 4/47 99/7206 0.0038030618241 ko05146 Amoebiasis 4/47 99/7206 0.0038030618241 ko05410 Hypertrophic cardiomyopathy (HCM) 4/47 100/7206 0.00394277855296 ko05200 Pathways in cancer 9/47 492/7206 0.00395228937472 ko05164 Influenza A 5/47 167/7206 0.00439908487683 ko00590 Arachidonic acid metabolism 3/47 52/7206 0.00459533745548 ko05161 Hepatitis B 5/47 173/7206 0.00510871930533 ko04930 Type II diabetes mellitus 3/47 54/7206 0.00511092298957 ko05206 MicroRNAs in cancer 5/47 177/7206 0.00562492111346 ko05321 Inflammatory bowel disease (IBD) 3/47 56/7206 0.00566011262353 ko05167 Kaposi's sarcoma-associated herpesvirus infection 5/47 191/7206 0.00772379808309 ko04660 T cell receptor signaling pathway 4/47 124/7206 0.00841937987588 ko01522 Endocrine resistance 4/47 124/7206 0.00841937987588 ko05145 Toxoplasmosis 4/47 126/7206 0.00889833037772 ko04915 Estrogen signaling pathway 4/47 131/7206 0.0101730848286 ko04630 Jak-STAT signaling pathway 4/47 132/7206 0.0104415467911 ko01523 Antifolate resistance 2/47 30/7206 0.0161273465162 ko04320 Dorso-ventral axis formation 2/47 31/7206 0.0171686457125 ko05220 Chronic myeloid leukemia 3/47 85/7206 0.0176866269689 ko05210 Colorectal cancer 3/47 86/7206 0.0182434232571 ko04510 Focal adhesion 5/47 240/7206 0.0193059759145 ko00562 Inositol phosphate metabolism 3/47 89/7206 0.0199722639978 ko04071 Sphingolipid signaling pathway 4/47 162/7206 0.0207403258151 ko04611 Platelet activation 4/47 163/7206 0.0211622918502 ko05120 Epithelial cell signaling in Helicobacter pylori infection 3/47 92/7206 0.02178898696 ko04672 Intestinal immune network for IgA production 2/47 37/7206 0.023990019223 ko04650 Natural killer cell mediated cytotoxicity 3/47 97/7206 0.025012549741 ko05418 Fluid shear stress and atherosclerosis 4/47 173/7206 0.0256753271698 ko05224 Breast cancer 4/47 174/7206 0.0261562886507 ko04623 Cytosolic DNA-sensing pathway 2/47 41/7206 0.0290559509118 ko04659 Th17 cell differentiation 3/47 106/7206 0.0314309242846 ko05215 Prostate cancer 3/47 111/7206 0.0353370901721 ko04070 Phosphatidylinositol signaling system 3/47 112/7206 0.0361472931118 ko05414 Dilated cardiomyopathy 3/47 112/7206 0.0361472931118 ko04215 Apoptosis - multiple species 2/47 47/7206 0.0373739041154 ko04072 Phospholipase D signaling pathway 4/47 197/7206 0.0387411569616 ko04151 PI3K-Akt signaling pathway 6/47 390/7206 0.0397451118359 ko04062 Chemokine signaling pathway 4/47 201/7206 0.0412314152944 ko05162 Measles 3/47 120/7206 0.042973226437 ko04921 Oxytocin signaling pathway 4/47 209/7206 0.0464821403853 ko05416 Viral myocarditis 2/47 55/7206 0.0496909023677