ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 18/219 152/7206 6.78385207837e-07 ko04024 cAMP signaling pathway 25/219 279/7206 1.00201935397e-06 ko05032 Morphine addiction 14/219 110/7206 5.24820543627e-06 ko04713 Circadian entrainment 15/219 136/7206 1.43259476837e-05 ko04723 Retrograde endocannabinoid signaling 17/219 175/7206 2.08883906654e-05 ko00604 Glycosphingolipid biosynthesis - ganglio series 5/219 14/7206 3.96347553632e-05 ko05033 Nicotine addiction 9/219 56/7206 4.10139197477e-05 ko04727 GABAergic synapse 12/219 110/7206 0.00011678704006 ko04915 Estrogen signaling pathway 13/219 131/7206 0.00016114848113 ko04921 Oxytocin signaling pathway 17/219 209/7206 0.00019523587303 ko04925 Aldosterone synthesis and secretion 11/219 105/7206 0.00032162825821 ko05030 Cocaine addiction 9/219 73/7206 0.000335867531492 ko04725 Cholinergic synapse 14/219 160/7206 0.000342781791219 ko04261 Adrenergic signaling in cardiomyocytes 16/219 205/7206 0.000479177711417 ko04728 Dopaminergic synapse 15/219 185/7206 0.000481298018573 ko04923 Regulation of lipolysis in adipocytes 9/219 77/7206 0.00050243748459 ko04720 Long-term potentiation 10/219 99/7206 0.00080159515995 ko04010 MAPK signaling pathway 21/219 321/7206 0.00117147604774 ko05031 Amphetamine addiction 9/219 91/7206 0.00169121168244 ko04144 Endocytosis 21/219 342/7206 0.00184438239701 ko04721 Synaptic vesicle cycle 8/219 80/7206 0.00282887540821 ko04022 cGMP-PKG signaling pathway 15/219 216/7206 0.00347799743529 ko00515 Mannose type O-glycan biosynthesis 4/219 25/7206 0.00635532681639 ko05414 Dilated cardiomyopathy 9/219 112/7206 0.00685591709796 ko04072 Phospholipase D signaling pathway 13/219 197/7206 0.00896948315406 ko04020 Calcium signaling pathway 16/219 265/7206 0.00898507940906 ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series 4/219 28/7206 0.00958200500499 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 7/219 79/7206 0.00987865588429 ko00440 Phosphonate and phosphinate metabolism 2/219 6/7206 0.0127219959448 ko04914 Progesterone-mediated oocyte maturation 8/219 104/7206 0.0135460814855 ko04930 Type II diabetes mellitus 5/219 54/7206 0.0234161908429 ko04970 Salivary secretion 7/219 95/7206 0.0251308302128 ko04911 Insulin secretion 8/219 117/7206 0.02572315183 ko04270 Vascular smooth muscle contraction 10/219 154/7206 0.026846406714 ko04080 Neuroactive ligand-receptor interaction 21/219 423/7206 0.0268696469437 ko00750 Vitamin B6 metabolism 2/219 9/7206 0.0287519809211 ko04722 Neurotrophin signaling pathway 10/219 160/7206 0.0304380186352 ko04211 Longevity regulating pathway 8/219 123/7206 0.0333462608427 ko04742 Taste transduction 5/219 61/7206 0.0372041550702