ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	152/799	423/7206	8.84081471976e-45
ko05033	Nicotine addiction	43/799	56/7206	1.39626457919e-30
ko04724	Glutamatergic synapse	72/799	152/7206	5.35977394117e-30
ko04721	Synaptic vesicle cycle	44/799	80/7206	4.60548031667e-22
ko05032	Morphine addiction	52/799	110/7206	7.39031763584e-22
ko04727	GABAergic synapse	51/799	110/7206	5.55974845092e-21
ko04728	Dopaminergic synapse	68/799	185/7206	1.23642099799e-20
ko04713	Circadian entrainment	54/799	136/7206	2.38768734145e-18
ko04723	Retrograde endocannabinoid signaling	62/799	175/7206	5.72561447974e-18
ko04725	Cholinergic synapse	58/799	160/7206	2.05637562487e-17
ko04024	cAMP signaling pathway	79/799	279/7206	4.83290398665e-16
ko04911	Insulin secretion	43/799	117/7206	1.87845609753e-13
ko05031	Amphetamine addiction	37/799	91/7206	2.48654081307e-13
ko04726	Serotonergic synapse	44/799	137/7206	2.04494174017e-11
ko04742	Taste transduction	27/799	61/7206	4.18693107364e-11
ko04921	Oxytocin signaling pathway	57/799	209/7206	5.31197586749e-11
ko04720	Long-term potentiation	35/799	99/7206	1.22285108148e-10
ko04261	Adrenergic signaling in cardiomyocytes	55/799	205/7206	1.94239463862e-10
ko04020	Calcium signaling pathway	65/799	265/7206	3.5545532565e-10
ko05030	Cocaine addiction	27/799	73/7206	5.33008871055e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	25/799	74/7206	1.5664287622e-07
ko04966	Collecting duct acid secretion	13/799	26/7206	9.12014052233e-07
ko04514	Cell adhesion molecules (CAMs)	34/799	130/7206	1.27009661894e-06
ko03040	Spliceosome	1/799	145/7206	1.34182921332e-06
ko04010	MAPK signaling pathway	64/799	321/7206	1.79061139185e-06
ko04925	Aldosterone synthesis and secretion	29/799	105/7206	2.01077391917e-06
ko04971	Gastric acid secretion	27/799	98/7206	4.75584572656e-06
ko05203	Viral carcinogenesis	10/799	277/7206	8.57716182481e-06
ko05168	Herpes simplex infection	4/799	182/7206	1.11664900789e-05
ko04060	Cytokine-cytokine receptor interaction	5/799	191/7206	1.95699019896e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/799	79/7206	2.98008521222e-05
ko04970	Salivary secretion	25/799	95/7206	3.83991943183e-05
ko04360	Axon guidance	47/799	233/7206	4.30669012574e-05
ko05164	Influenza A	4/799	167/7206	4.7870841201e-05
ko05110	Vibrio cholerae infection	18/799	63/7206	0.000108416329713
ko04745	Phototransduction - fly	13/799	38/7206	0.000133261869603
ko04621	NOD-like receptor signaling pathway	4/799	157/7206	0.000145352536888
ko04120	Ubiquitin mediated proteolysis	3/799	138/7206	0.000163314510161
ko03013	RNA transport	5/799	166/7206	0.000230768243878
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/799	14/7206	0.000341353345477
ko04740	Olfactory transduction	20/799	80/7206	0.000417250166721
ko04260	Cardiac muscle contraction	23/799	98/7206	0.000463885505407
ko04014	Ras signaling pathway	50/799	279/7206	0.000595145981985
ko04972	Pancreatic secretion	25/799	111/7206	0.000596794142071
ko04730	Long-term depression	19/799	78/7206	0.000770491471343
ko05322	Systemic lupus erythematosus	5/799	151/7206	0.000898012792804
ko04750	Inflammatory mediator regulation of TRP channels	26/799	122/7206	0.00110145805444
ko04744	Phototransduction	11/799	36/7206	0.00128130058125
ko03008	Ribosome biogenesis in eukaryotes	1/799	79/7206	0.00176007778536
ko04141	Protein processing in endoplasmic reticulum	8/799	184/7206	0.0017933475801
ko04626	Plant-pathogen interaction	7/799	18/7206	0.00212442918768
ko04612	Antigen processing and presentation	1/799	77/7206	0.0027308842118
ko04915	Estrogen signaling pathway	26/799	131/7206	0.0028332826101
ko05162	Measles	4/799	120/7206	0.00314164787271
ko05414	Dilated cardiomyopathy	23/799	112/7206	0.00337603250036
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/799	92/7206	0.00370480419985
ko04350	TGF-beta signaling pathway	3/799	103/7206	0.00404125938987
ko05161	Hepatitis B	8/799	173/7206	0.00442543624937
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/799	59/7206	0.00522688324185
ko04072	Phospholipase D signaling pathway	35/799	197/7206	0.00534235504985
ko05169	Epstein-Barr virus infection	11/799	206/7206	0.00646386684508
ko04140	Autophagy - animal	8/799	164/7206	0.0078054563644
ko04022	cGMP-PKG signaling pathway	37/799	216/7206	0.00780716664743
ko04064	NF-kappa B signaling pathway	3/799	96/7206	0.00810037802966
ko04640	Hematopoietic cell lineage	1/799	64/7206	0.00832116595106
ko04540	Gap junction	24/799	128/7206	0.00970406731349
ko05166	HTLV-I infection	19/799	292/7206	0.00986118891313
ko04110	Cell cycle	7/799	145/7206	0.0109600186551
ko00512	Mucin type O-glycan biosynthesis	8/799	29/7206	0.0113298767472
ko04070	Phosphatidylinositol signaling system	21/799	112/7206	0.0143473133048
ko05140	Leishmaniasis	2/799	75/7206	0.0148465318284
ko04924	Renin secretion	17/799	86/7206	0.0149181847623
ko04146	Peroxisome	3/799	89/7206	0.0160884027517
ko04550	Signaling pathways regulating pluripotency of stem cells	9/799	165/7206	0.0167065818254
ko05205	Proteoglycans in cancer	18/799	271/7206	0.0174241227948
ko04976	Bile secretion	16/799	80/7206	0.0180838927019
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/799	15/7206	0.0192388841524
ko04214	Apoptosis - fly	2/799	72/7206	0.0214764130376
ko05215	Prostate cancer	5/799	111/7206	0.0217322141076
ko00310	Lysine degradation	2/799	73/7206	0.0220626957173
ko05323	Rheumatoid arthritis	17/799	89/7206	0.0251231735198
ko00590	Arachidonic acid metabolism	1/799	52/7206	0.0262789228337
ko00480	Glutathione metabolism	1/799	55/7206	0.0275545791049
ko00240	Pyrimidine metabolism	5/799	110/7206	0.0303262833885
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/799	182/7206	0.0303334720735
ko04630	Jak-STAT signaling pathway	7/799	132/7206	0.0344524964188
ko05034	Alcoholism	37/799	238/7206	0.0349073891107
ko04964	Proximal tubule bicarbonate reclamation	7/799	29/7206	0.0354189228068
ko05410	Hypertrophic cardiomyopathy (HCM)	18/799	100/7206	0.0355533954628
ko05010	Alzheimer's disease	32/799	202/7206	0.0396872381048
ko04912	GnRH signaling pathway	21/799	122/7206	0.0401416765986
ko04722	Neurotrophin signaling pathway	26/799	160/7206	0.0412215102008
ko04330	Notch signaling pathway	2/799	62/7206	0.0423614730787
ko00561	Glycerolipid metabolism	2/799	63/7206	0.0424278046158
ko01524	Platinum drug resistance	3/799	76/7206	0.0429067166505
ko00513	Various types of N-glycan biosynthesis	9/799	42/7206	0.0446488690771
ko04930	Type II diabetes mellitus	11/799	54/7206	0.0456029397281
ko04510	Focal adhesion	17/799	240/7206	0.0463737880399