ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	170/949	423/7206	3.28581434137e-47
ko04724	Glutamatergic synapse	85/949	152/7206	1.17060874387e-36
ko05033	Nicotine addiction	47/949	56/7206	3.52213689939e-33
ko05032	Morphine addiction	65/949	110/7206	3.83163387415e-30
ko04727	GABAergic synapse	63/949	110/7206	3.6588795037e-28
ko04713	Circadian entrainment	69/949	136/7206	1.8841938563e-26
ko04728	Dopaminergic synapse	81/949	185/7206	2.32153808617e-25
ko04725	Cholinergic synapse	72/949	160/7206	1.64724509524e-23
ko04723	Retrograde endocannabinoid signaling	74/949	175/7206	4.03951630929e-22
ko04024	cAMP signaling pathway	92/949	279/7206	2.34744235288e-18
ko04911	Insulin secretion	52/949	117/7206	5.49153378956e-17
ko04921	Oxytocin signaling pathway	74/949	209/7206	7.43435411124e-17
ko04020	Calcium signaling pathway	84/949	265/7206	1.14686383999e-15
ko04726	Serotonergic synapse	55/949	137/7206	1.62177231668e-15
ko05031	Amphetamine addiction	41/949	91/7206	6.66273106897e-14
ko04721	Synaptic vesicle cycle	38/949	80/7206	6.84811919169e-14
ko04742	Taste transduction	32/949	61/7206	1.99062643408e-13
ko04261	Adrenergic signaling in cardiomyocytes	67/949	205/7206	2.01399369048e-13
ko04720	Long-term potentiation	42/949	99/7206	4.13243300461e-13
ko04744	Phototransduction	21/949	36/7206	2.07275429374e-10
ko04925	Aldosterone synthesis and secretion	38/949	105/7206	1.45720448035e-09
ko04971	Gastric acid secretion	36/949	98/7206	2.47471619194e-09
ko04970	Salivary secretion	35/949	95/7206	3.77542813606e-09
ko04010	MAPK signaling pathway	79/949	321/7206	1.45350589776e-08
ko03040	Spliceosome	1/949	145/7206	3.66099552126e-08
ko05030	Cocaine addiction	28/949	73/7206	5.05188951653e-08
ko05203	Viral carcinogenesis	10/949	277/7206	5.76557977654e-08
ko04740	Olfactory transduction	29/949	80/7206	1.24677563824e-07
ko04360	Axon guidance	60/949	233/7206	1.73041453723e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	27/949	74/7206	2.90971427996e-07
ko04972	Pancreatic secretion	35/949	111/7206	4.79836016803e-07
ko04022	cGMP-PKG signaling pathway	55/949	216/7206	9.82632787951e-07
ko04072	Phospholipase D signaling pathway	50/949	197/7206	2.87569418613e-06
ko04060	Cytokine-cytokine receptor interaction	6/949	191/7206	3.40416406589e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/949	79/7206	4.5727119442e-06
ko05168	Herpes simplex infection	6/949	182/7206	6.6291402984e-06
ko04730	Long-term depression	25/949	78/7206	1.17886182461e-05
ko05322	Systemic lupus erythematosus	4/949	151/7206	1.36159715404e-05
ko04514	Cell adhesion molecules (CAMs)	35/949	130/7206	2.06798131342e-05
ko03013	RNA transport	6/949	166/7206	3.8894646765e-05
ko04745	Phototransduction - fly	15/949	38/7206	4.48154013123e-05
ko04070	Phosphatidylinositol signaling system	31/949	112/7206	5.06699803548e-05
ko04260	Cardiac muscle contraction	28/949	98/7206	5.39436902402e-05
ko04141	Protein processing in endoplasmic reticulum	8/949	184/7206	9.09375368459e-05
ko05414	Dilated cardiomyopathy	30/949	112/7206	0.000100434542989
ko05164	Influenza A	7/949	167/7206	0.0001709607789
ko04014	Ras signaling pathway	59/949	279/7206	0.000188173886116
ko04915	Estrogen signaling pathway	33/949	131/7206	0.000197304681445
ko04750	Inflammatory mediator regulation of TRP channels	31/949	122/7206	0.000214613026017
ko03008	Ribosome biogenesis in eukaryotes	1/949	79/7206	0.000315490789328
ko04110	Cell cycle	6/949	145/7206	0.000431716991753
ko04621	NOD-like receptor signaling pathway	7/949	157/7206	0.000455876750309
ko04612	Antigen processing and presentation	1/949	77/7206	0.000489660360993
ko04540	Gap junction	31/949	128/7206	0.000535642761648
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/949	59/7206	0.000619540585292
ko05169	Epstein-Barr virus infection	12/949	206/7206	0.000760839325532
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/949	14/7206	0.000992863596468
ko04924	Renin secretion	22/949	86/7206	0.00185327152311
ko04371	Apelin signaling pathway	38/949	177/7206	0.00215231727453
ko04640	Hematopoietic cell lineage	1/949	64/7206	0.00236352957909
ko05410	Hypertrophic cardiomyopathy (HCM)	24/949	100/7206	0.0026413295698
ko04912	GnRH signaling pathway	28/949	122/7206	0.00267490899445
ko04015	Rap1 signaling pathway	54/949	278/7206	0.00271785969605
ko04350	TGF-beta signaling pathway	4/949	103/7206	0.00290006746147
ko04120	Ubiquitin mediated proteolysis	7/949	138/7206	0.00310682568583
ko00240	Pyrimidine metabolism	5/949	110/7206	0.00416067371468
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/949	182/7206	0.00539476214614
ko04064	NF-kappa B signaling pathway	4/949	96/7206	0.00565113761184
ko05205	Proteoglycans in cancer	21/949	271/7206	0.00582514690955
ko00480	Glutathione metabolism	1/949	55/7206	0.00781633831024
ko04916	Melanogenesis	30/949	142/7206	0.00793340171178
ko04918	Thyroid hormone synthesis	20/949	86/7206	0.00940614927034
ko05016	Huntington's disease	16/949	215/7206	0.0101399771105
ko04114	Oocyte meiosis	29/949	139/7206	0.0106943162093
ko04146	Peroxisome	4/949	89/7206	0.0109337540039
ko04976	Bile secretion	19/949	80/7206	0.0112193221071
ko05161	Hepatitis B	12/949	173/7206	0.011914291094
ko04630	Jak-STAT signaling pathway	8/949	132/7206	0.0128916750538
ko04930	Type II diabetes mellitus	14/949	54/7206	0.0129229546225
ko05162	Measles	7/949	120/7206	0.0136787797802
ko04210	Apoptosis	13/949	180/7206	0.0138836237814
ko04142	Lysosome	10/949	151/7206	0.0144121248151
ko05140	Leishmaniasis	3/949	75/7206	0.0149825474545
ko00260	Glycine, serine and threonine metabolism	1/949	48/7206	0.0167976276158
ko05219	Bladder cancer	1/949	48/7206	0.0167976276158
ko04217	Necroptosis	13/949	178/7206	0.0178853046133
ko05034	Alcoholism	44/949	238/7206	0.0188041442306
ko04973	Carbohydrate digestion and absorption	11/949	42/7206	0.0199542460254
ko05231	Choline metabolism in cancer	27/949	134/7206	0.0200539382523
ko00330	Arginine and proline metabolism	2/949	61/7206	0.0202847780369
ko04137	Mitophagy - animal	4/949	82/7206	0.0209360208615
ko04214	Apoptosis - fly	3/949	72/7206	0.021143361361
ko03018	RNA degradation	4/949	84/7206	0.0214577595937
ko00310	Lysine degradation	3/949	73/7206	0.0217004844213
ko04626	Plant-pathogen interaction	6/949	18/7206	0.023411763267
ko04922	Glucagon signaling pathway	26/949	128/7206	0.0238214886857
ko03022	Basal transcription factors	1/949	44/7206	0.024645716899
ko00071	Fatty acid degradation	1/949	45/7206	0.0248432153226
ko03420	Nucleotide excision repair	1/949	46/7206	0.025529333739
ko04140	Autophagy - animal	12/949	164/7206	0.0256392443198
ko04923	Regulation of lipolysis in adipocytes	17/949	77/7206	0.0267650167287
ko00562	Inositol phosphate metabolism	19/949	89/7206	0.0270261247405
ko05321	Inflammatory bowel disease (IBD)	2/949	56/7206	0.0281184037342
ko04270	Vascular smooth muscle contraction	30/949	154/7206	0.0290782715121
ko03320	PPAR signaling pathway	3/949	69/7206	0.0297360852547
ko05215	Prostate cancer	7/949	111/7206	0.0325529029264
ko04657	IL-17 signaling pathway	5/949	87/7206	0.0374424395617
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/949	15/7206	0.0378173355485
ko01524	Platinum drug resistance	4/949	76/7206	0.0395985992052
ko05145	Toxoplasmosis	9/949	126/7206	0.0453004165279
ko00190	Oxidative phosphorylation	9/949	127/7206	0.0457038706225
ko04071	Sphingolipid signaling pathway	30/949	162/7206	0.0458195280995
ko00512	Mucin type O-glycan biosynthesis	8/949	29/7206	0.0461998145573
ko04964	Proximal tubule bicarbonate reclamation	8/949	29/7206	0.0461998145573